An observational study in Post-induction Hypotension (PIH), sponsored by Avicenna Military Hospital. Completed at 1 site in Morocco. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-04-08.
Sponsored by Avicenna Military Hospital · Observational
This study evaluated the occurrence of post-induction hypotension (PIH) in patients undergoing elective surgery under general anesthesia. PIH is a common perioperative complication associated with adverse outcomes.
Using previously collected clinical and echocardiographic data, the study explored the relationship between pre-induction hemodynamic status and the risk of developing PIH.
The findings may help improve preoperative risk stratification and support more individualized perioperative hemodynamic management.
Post-induction hypotension (PIH) was recognized as a common and clinically significant complication associated with adverse perioperative outcomes. This study was conducted as a retrospective analysis of prospectively collected data from adult patients undergoing elective surgery under general anesthesia.
The objective was to evaluate whether pre-induction hemodynamic status, assessed using echocardiographic parameters and routine clinical variables, was associated with the occurrence and timing of PIH. The analysis focused on identifying distinct hemodynamic profiles reflecting underlying cardiovascular physiology.
Unsupervised clustering (k-means) was applied to pre-induction variables to identify phenotypes, and principal component analysis was used to explore variable contributions. Latent profile analysis was performed as a sensitivity analysis. The association between phenotypes and PIH was assessed using time-to-event analysis.
No additional interventions were performed, and patient management was not influenced by the study. All analyses were conducted on anonymized data.
This study aimed to improve the understanding of variability in hemodynamic responses to anesthesia induction and to support future strategies for individualized perioperative care.
885 studies on the registry are indexed under Hypotension; 195 are open to participants now.
This study's enrollment of 64 is below the median of 90 across 265 observational studies indexed under Hypotension.
Browse Hypotension studies →Avicenna Military Hospital is the lead sponsor of 8 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients aged over 50 years scheduled for elective abdominal surgery under general anesthesia.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Patients scheduled for elective abdominal surgery under genral anesthesia.
Exclusion Criteria:
Adult patients undergoing elective surgery under general anesthesia included in a retrospective analysis of prospectively collected data.
Pre-induction hemodynamic phenotype classification
Pre-induction hemodynamic phenotypes were derived using unsupervised clustering of clinical and echocardiographic variables obtained prior to anesthesia induction.
Time frame: pre-induction, before administration of general anesthesia: from admission to the operating to induction of general anesthesia
Pre-induction hemodynamic phenotype classification
Pre-induction hemodynamic phenotypes were derived using unsupervised clustering of clinical and echocardiographic variables obtained prior to anesthesia induction.
Time frame: Baseline (pre-induction, before administration of general anesthesia)
Plan to share: Yes — De-identified individual participant data (including clinical and echocardiographic variables underlying the reported results) will be made available upon reasonable request from qualified healthcare providers or researchers. Data sharing will be subject to approval by the study investigators and compliance with institutional and ethical regulations. Requests must include a methodologically sound proposal and will be evaluated to ensure appropriate use of the data.
Supporting information: Study protocol, Statistical analysis plan, Clinical study report
Time frame: April 30th, 2026
Access criteria: Qualified healthcare providers or researchers De-identified individual participant data (including clinical and echocardiographic variables underlying the reported results)
This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Avicenna Military Hospital