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CompletedNCT07471711Updated Mar 13, 2026

A Multifunctional Miniature Nephroscope for Percutaneous Nephrolithotomy

An interventional study of percutaneous nephrolithotomy in Urolithiasis and Percutaneous Nephrolithotomy (PCNL), sponsored by The First Affiliated Hospital of Guangzhou Medical University. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2026-03-13.

Sponsored by The First Affiliated Hospital of Guangzhou Medical University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 3 years 8 months after the study started (first participant enrolled Jul 2022, registered Mar 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
216
Allocation
Not applicable
Sex
All
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Study summary

The goal of this clinical trial is to introduce a novel multifunctional miniature endoscopic system, namely "Aircraft Nephroscope", for percutaneous nephrolithotomy (PCNL) to treat the patients with urolithiasis. The main questions it aims to answer are:

  1. Is the "Aircraft Nephroscope" a safe and efficient instrument for PCNL?
  2. What types of nephrocope the "Aircraft Nephroscope" is and what function does it have? Researchers will observe the surgical outcome through the stone-free rate and compliction rates.

Participants will:

  1. Undergo PCNL with "Aircraft Nephroscope"
  2. Follow-up the stone-free rate for 2 weeks after surgery
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Conditions studied

  • Urolithiasis
  • Percutaneous Nephrolithotomy (PCNL)

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03

In context

Urolithiasis

278 studies on the registry are indexed under Urolithiasis; 70 are open to participants now.

This study's enrollment of 216 is above the median of 100 across 197 interventional studies indexed under Urolithiasis.

Browse Urolithiasis studies →

Lead sponsor

The First Affiliated Hospital of Guangzhou Medical University is the lead sponsor of 158 studies on the registry; 65 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Serum creatinine (≤200 μmol/l);
  2. American Society of Anesthesiology score of 1-3;
  3. Agree to undergo PCNL with "Aircraft Nephroscope", provide written informed consent and adhere to the requirements of the trial.

Exclusion criteria

Exclusion Criteria:

  1. Patients with histories of renal transplant or urinary diversion;
  2. patients with congenital abnormalities;
  3. Pregnant patients;
  4. Patients with uncorrected coagulopathy and
  5. Patients with active urinary tract infections.
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
216 participants (actual)

Study arms

  • Experimental
    Charateristcs of a multifunctional miniature nephroscope for percutaneous nephrolithotomy

    Procedure: percutaneous nephrolithotomy

Interventions

  • Procedurepercutaneous nephrolithotomy

    After all the preparations of the procedure, the operator could select the appropriate nephroscope based on the stone burden. It was feasible and efficient to use the F17 nephroscope for the removal of large and soft calculi through ultrasonic lithotripsy. If the stones were hard and large, it would be advisable to select the F12 nephroscope for stone removal through pneumatic lithotripsy or by using a laser fiber, and the negative pressure suction function could enhance efficiency. To minimize the wound size, it was advisable to select the F8 nephroscope for small stones and utilize its suction-evacuation function to extract the stones. For complex kidney stones, including multiple stones or staghorn stones, surgeons can choose from combinations of the F8 nephroscope, F12 nephroscope, and F17 nephroscope to completely remove the stones.

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What researchers measure

Primary outcomes

  1. Stone-free rate

    Time frame: From enrollment to the end of treatment at 2 weeks

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Study locations

1 site
  • the First Affiliated Hospital of Guangzhou Medical University
    Guangzhou, Guangdong / 广东 510120, China
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 13, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07471711
Lead sponsor
The First Affiliated Hospital of Guangzhou Medical University
Responsible party
Yongda Liu (Director of the Urology Department in First Affiliated Hospital of Guangzhou Medical University, The First Affiliated Hospital of Guangzhou Medical University) — Principal investigator
First posted
Mar 13, 2026
Start date
Jul 1, 2022
Primary completion
Jun 30, 2024
Completion
Jun 30, 2024
Last update
Mar 13, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.

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