ClinicalTrials.gg
CompletedNCT07321743Updated Jan 7, 2026

Emergency Intestinal Anastmosis

An interventional study of emergency intestinal anastmosis surgery in Intestinal Anastomosis, sponsored by Zagazig University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-01-07.

Sponsored by Zagazig University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year after the study started (first participant enrolled Dec 2024, registered Dec 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this clinical trial is to compare the outcomes of emergency intestinal anastomosis after stapled and handsewn anastmosis. The main question it aims to answer are:

Is stapled intestinal anastmosis is better than handsewn anastmosis in emergency laparotomy?

Participants at surgical emergency unit:

  • Had intestinal anastmosis either by stapler or handsewn.
  • kept in hospital for follow up and detection of complications like wound infection and leakage.
  • Either discharged or managed according to the complications
  • Outcomes were compared between the two groups
02

Conditions studied

  • Intestinal Anastomosis

Keywords

  • stapler
  • handsewn
  • anastomotic leakage
  • intestinal obstruction
03

In context

Anastomotic Leak

240 studies on the registry are indexed under Anastomotic Leak; 72 are open to participants now.

This study's enrollment of 90 is below the median of 140 across 128 interventional studies indexed under Anastomotic Leak.

Browse Anastomotic Leak studies →

Lead sponsor

Zagazig University is the lead sponsor of 459 studies on the registry; 77 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • patients admitted to emergency surgery and needed intestinal anastmosis

Exclusion criteria

Exclusion Criteria:

  • patients below 18 years old
  • immune-compromised patients e.g. therapy, autoimmue disease
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
90 participants (actual)

Study arms

  • Active comparator
    stapled group

    Procedure: emergency intestinal anastmosis surgery

  • Active comparator
    handsewn group

    Procedure: emergency intestinal anastmosis surgery

Interventions

  • Procedureemergency intestinal anastmosis surgery

    cases with intestinal trauma, perforation or intestinal obstruction had emergency laparotomy and intestinal anastmosis was done

06

What researchers measure

Primary outcomes

  1. intestinal leakage

    intestinal leakage output calculated in ml by weighing dressing or calculating the drain output

    Time frame: from one day to two weeks after surgery

Secondary outcomes

  1. operation time

    operation time in minutes was calculated

    Time frame: from incision time to closure (0 to 5 hours)

  2. bleeding

    bleeding amount was calculated in ml

    Time frame: from one hour to two days after surgery

  3. hospital stay

    hospital stay was recorded in days

    Time frame: from one day to one month after surgery

  4. post-operative pain

    pain was evaluated by the visual analogue scale from 1 to 10. score 1 means least painful, score 10 means very painful

    Time frame: from one to three days after after surgery

07

Study locations

1 site
  • faculty of medicine, Zagazig University
    Zagazig, Sharqia Province 44519, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 7, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07321743
Lead sponsor
Zagazig University
Responsible party
Reham Zakaria Mohamed Ahmed (lecturer of general surgery, Zagazig University, Zagazig University) — Principal investigator
First posted
Jan 7, 2026
Start date
Dec 20, 2024
Primary completion
Dec 20, 2025
Completion
Dec 20, 2025
Last update
Jan 7, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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