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RecruitingNCT07715500Updated Jul 20, 2026

Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications

An interventional study of Magnetic Resonance Cholangiopancreatography in Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications and Donor Hepatectomy, sponsored by Institute of Liver and Biliary Sciences, India. Recruiting at 1 site in India. Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2026-07-20.

Sponsored by Institute of Liver and Biliary Sciences, India · Not applicable, Interventional, and Diagnostic

From the registry’s dates

  • Primary completion was expected by Jul 2026, 3 months ago, but the record still lists the study as recruiting.
  • Registered 6 months after the study started (first participant enrolled Jul 2025, registered Jan 2026).
  • Started Jul 2025; still recruiting 1 year 4 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Randomized
Ages
18 Years to 55 Years
Sex
All
01

Study summary

Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the "Achilles heel" of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential

Read the detailed description

Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the "Achilles heel" of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential

02

Conditions studied

  • Chronic Liver Disease and Cirrhosis
  • Liver Transplant; Complications
  • Donor Hepatectomy

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Keywords

  • Liver Transplantation
  • Magnetic Resonance Cholangiopancreatography
  • Liver donors
03

In context

Fibrosis

1,270 studies on the registry are indexed under Fibrosis; 276 are open to participants now.

This study's planned enrollment of 100 is above the median of 63 across 840 interventional studies indexed under Fibrosis.

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Lead sponsor

Institute of Liver and Biliary Sciences, India is the lead sponsor of 302 studies on the registry; 87 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All prospective voluntary healthy liver donor of age 18-55

Exclusion criteria

Exclusion Criteria:

  • Type C/D Portal vein anatomy
  • Left sided Gallbladder
  • Right Posterior Graft
  • Recipients undergoing Hepaticojejunostomy
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
100 participants (estimated)

Study arms

  • No intervention
    No MRCP GROUP

    Magnetic Resonance Cholangiopancreatography is not done as part of Routine Liver donor workup

  • Experimental
    MRCP GROUP

    Magnetic Resonance Cholangiopancreatography is done as part of Routine Liver donor workup

    Diagnostic Test: Magnetic Resonance Cholangiopancreatography

Interventions

  • Diagnostic testMagnetic Resonance Cholangiopancreatography

    Magnetic Resonance Cholangiopancreatography is being excluded from list of Investigation as part of Non inferiority trial

06

What researchers measure

Primary outcomes

  1. To identify factors causing early biliary complications like type and number of arterial & biliary reconstruction, type of graft, number & size of Bile ducts in donor in both groups

    Time frame: 6 month of postop

Secondary outcomes

  1. Donor biliary complications in both group

    Bile leak or strictures in Liver Donors

    Time frame: 1 month of postoperative period

  2. Identify Risk factors for early Biliary complications in recipients

    Identify Risk factors for early Biliary complications in recipients

    Time frame: till 6 months of Post operative period of Liver transplant

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 20, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07715500
Responsible party
Sponsor
First posted
Jul 20, 2026
Start date
Jul 1, 2025
Primary completion
Jul 15, 2026 (estimated)
Completion
Aug 30, 2026 (estimated)
Last update
Jul 20, 2026

Study contacts

Dr Atul Renjit, MBBS, MS, DNB
Contact
atulrenjit@gmail.com
+91 9632060230
Dr Nilesh Sadashiv Patil, MCH
Contact

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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