A Phase 2/3 interventional study of Tranexamic Acid (TXA) in Hemoptysis, NEBULIZATION and Tranexamic Acid, sponsored by University of Health Sciences Lahore. Completed at 1 site in Pakistan. Open to participants aged 12 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-11-28.
Sponsored by University of Health Sciences Lahore · Phase 2/3, Interventional, and Treatment
This study compares the effect of tranexamic acid on hemoptysis when given through the conventional IV route and Through nebulization.
The investigators are conducting a randomized controlled trial for the comparison of routes through which tranexamic acid can be given to control hemoptysis. The study participants will be divided into 2 groups randomly and 1 group will be assigned to use IV route while other will be assigned the nebulization route and the result variables include the time taken for complete control of hemoptysis and recurrence time. Another variable is the reduction in amout of blood in sputum after each intervention.
37 studies on the registry are indexed under Hemoptysis; 6 are open to participants now.
This study's enrollment of 172 is above the median of 73 across 20 interventional studies indexed under Hemoptysis.
Browse Hemoptysis studies →University of Health Sciences Lahore is the lead sponsor of 83 studies on the registry; 52 are open to participants now.
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Exclusion Criteria:
Tranexamic acid has been used conventionally for hemoptysis via IV route
Drug: Tranexamic Acid (TXA)
Tranexamic acid when given through nebulization can be more effective than IV route in controlling hemoptysis
Drug: Tranexamic Acid (TXA)
In this study we are comparing the effect of tranexamic acid on hemoptysis when given through IV route and nebulization
Also known as: nebulization
Time to control hemoptysis
In this study the time taken by tranexamic acid to acehive comolete control of hemoptysis will be compared when given through IV and nebulization.
Time frame: 48 hours
Plan to share: No
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Tranexamic Acid
University of Health Sciences Lahore