ClinicalTrials.gg
CompletedNCT07202650Updated Oct 22, 2026

THE EFFECT OF GUİDED IMAGERY ON PREMENSTRUAL SYNDROME

An interventional study of guided imagery in Guided Imagery, Premenstrual Syndrome and Nursing, sponsored by Baskent University. Completed at 1 site in Turkey (Türkiye). Open to female participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-22.

Sponsored by Baskent University · Not applicable, Interventional, and Supportive care

Updated Oct 22, 2026Now CompletedPrimary completion moved+2 moreGo to Updates ↓

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Phase
Not applicable
Study type
Interventional
Enrollment
61
Allocation
Randomized
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 62 studies in Premenstrual Syndrome with a site in Turkey — 10 open to participants now, 11 under way, none of them phase 3. Premenstrual Syndrome · Turkey.

Enrollment
40th of 58
61 · median 76
Started
2026
with 7 others
No phase
58 of 62
10 open now
Registered
50th of 62
by date

Among the 62 studies in Premenstrual Syndrome with a site in Turkey, this one is the 40th largest by enrollment of the 58 interventional ones that give a count, is one of 8 that started in 2026, is one of 58 with no phase, and was the 50th registered.

Premenstrual Syndrome

177 studies on the registry are indexed under Premenstrual Syndrome; 32 are open to participants now.

Browse Premenstrual Syndrome studies →

Open to participants now

10 of the 62 studies in Premenstrual Syndrome with a site in Turkey are open now. Recruiting first, the newest first:

5 more — sign in →

All 10 open studies →

A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →

Who these studies take

Of the 11 Premenstrual Syndrome studies recruiting now, none (0%) set no upper age limit and 11 (100%) stop at 75 or younger; none take children under 18; 9 take healthy volunteers.

This study: female · healthy volunteers too.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 62 studies in Premenstrual Syndrome with a site in Turkey, or all of them as a file.
02

Study summary

EFFECT OF GUIDED IMAGERY ON PREMENSTRUAL SYNDROME IN UNIVERSITY STUDENTS

Premenstrual Syndrome (PMS) is a condition characterized by physical, behavioral, and emotional symptoms that appear at the end of the luteal phase, 7-10 days before menstruation, and resolve with the onset of menstruation. Symptoms include irritability, loss of control, anxiety, depression, sleep disturbances, decreased concentration, unexplained crying, fatigue, weakness, changes in appetite, edema, headaches, joint and muscle pain, breast tenderness, altered sexual activity, and social withdrawal. In young women, PMS can negatively affect self-confidence, social relationships, quality of life, and academic performance.

PMS treatment aims to relieve both physical and psychological symptoms and may include dietary supplements and complementary-alternative therapies. Approaches such as reflexology, pilates, acupressure, music, exercise, and guided imagery have shown promising results in reducing premenstrual symptoms. Mind-body-based approaches in complementary therapies are known to support psychological well-being. Guided imagery, a form of mind-body communication, involves the flow of thoughts and the way the mind encodes, stores, and expresses sensory information. It is based on the understanding that the mind and body are interconnected and that mental processes can influence physical responses. Guided imagery has been shown to reduce stress, improve mood, enhance sleep quality, strengthen the immune system, reduce fatigue, and minimize nausea and vomiting.

Although effective, research on the use of guided imagery to reduce PMS symptoms in university students is limited. This study aims to investigate the effect of guided imagery on premenstrual syndrome in this population.

Read the detailed description

Premenstrual Syndrome (PMS) is a condition characterized by physical, behavioral, and emotional symptoms that typically occur at the end of the luteal phase of a woman's menstrual cycle, 7-10 days before menstruation, and resolve at the onset of menstruation or shortly afterward. When diagnosing PMS, women are advised to keep a symptom diary for at least two menstrual cycles. The diary should document symptoms during the luteal phase and the symptom-free period until ovulation. Underlying physical or psychological conditions that could exacerbate symptoms should also be considered.

PMS can be diagnosed when symptoms occur for at least three consecutive menstrual cycles, beginning within five days before menstruation, ending within four days after menstruation starts, and interfering with normal daily activities. Evaluations should also consider medical, psychological, sociocultural, and lifestyle factors.

Symptoms of PMS include irritability, feelings of loss of control, anxiety, depression, insomnia or hypersomnia, difficulty concentrating, crying for no reason, fatigue, increased appetite, edema, weight gain, dizziness, headaches, joint and muscle pain, breast tenderness, changes in sexual activity, and avoidance of social interactions, among over 200 psychological, physical, and behavioral symptoms. Up to 90% of women of reproductive age report experiencing one or more of these symptoms in the days before menstruation, which can affect behavior, well-being, and social or work environments.

Although the exact cause of PMS is not fully understood, it is believed that endocrine factors-such as carbohydrate intolerance, fluid retention, progesterone deficiency, estrogen imbalance, endorphin deficiency, adrenal or thyroid dysfunction, hyperprolactinemia, and hypoglycemia-along with psychological factors like genetics and stress, contribute to its development.

Traditionally considered a concern for women of reproductive age, PMS is increasingly recognized as a common mental health issue, significantly impairing daily functioning. The COVID-19 pandemic has also been associated with an increase in some PMS symptoms. The wide range of PMS symptoms makes it challenging to determine its true prevalence, which varies widely across studies. Women often use both pharmacological and non-pharmacological strategies to manage physical and psychological symptoms during the premenstrual period. PMS can negatively affect self-confidence, social relationships, quality of life, and academic performance, making effective treatment increasingly important.

Treatment focuses on alleviating both physical and psychiatric symptoms, and may include dietary supplements and complementary-alternative therapies. Complementary approaches such as reflexology, pilates, acupressure, music, exercise, and guided imagery have shown promising results in reducing premenstrual symptoms. Mind-body approaches in complementary therapies are known to have psychological benefits. Among these, relaxation techniques are the most commonly used, aiming to neutralize stress-related physical changes, including muscle tension, high blood pressure, and hormonal fluctuations, while calming the mind.

Guided imagery is a mind-body communication technique that involves the flow of thoughts and how the brain encodes, stores, and recalls sensory information. It is based on the connection between mind and body, recognizing that the mind can influence physiological responses. Stress and anxiety directly affect the brain and immune system. Guided imagery can be practiced with an instructor or through pre-recorded audio or video, and individuals can also practice self-directed imagery, creating their own scenarios. It can be applied in groups or individually. This technique has been shown to reduce stress, improve mood, strengthen the immune system, reduce fatigue, enhance sleep quality, and minimize nausea and vomiting.

Studies among university students have shown that guided imagery effectively alleviates premenstrual symptoms. Additionally, hypnotherapy and virtual reality-based relaxation interventions have been found to reduce PMS symptoms. However, research on using guided imagery specifically for reducing premenstrual symptoms in university students is still limited.

03

Conditions studied

  • Guided Imagery
  • Premenstrual Syndrome
  • Nursing

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Keywords

  • premenstrual syndrome
  • guided imagery
  • university students
  • quality of life
04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Regular menstrual cycles (21-35 days over the last three cycles)
  • Age 18 years or older
  • No medical treatment for PMS
  • Ability to communicate effectively in Turkish
  • No psychiatric diagnosis or gynecological disorder (e.g., abnormal uterine bleeding, myoma, ovarian cysts)
  • A score >89 on the Premenstrual Syndrome Scale (PMSS)
  • No prior participation in guided imagery training

Exclusion criteria

Exclusion Criteria:

  • Failure to perform guided imagery at the correct time or in the prescribed manner
  • Irregular menstruation during the last three months
  • Use of
  • Use of analgesics during menstruation while participating in the study
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Contraception

Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.

Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.

05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
61 participants (actual)

Study arms

  • Active comparator
    intervention group

    At baseline, students in both the intervention and control groups will complete the Introductory Characteristics Data Collection Form, the Premenstrual Syndrome Scale, and the WHO Quality of Life Scale. Students in the intervention group with high PMS scores will be instructed to practice guided imagery for 15 minutes daily during two consecutive menstrual cycles-specifically, during the seven days prior to menstruation when symptoms begin and the first four days of menstruation. The control group will receive no intervention. Throughout the study, intervention group participants will complete the Menstrual Cycle Follow-up Form and the Guided Imagery Follow-up Form, while control group participants will complete only the Menstrual Cycle Follow-up Form. After two cycles, both groups will again complete the Premenstrual Syndrome Scale and the WHO Quality of Life Scale.

    Behavioral: guided imagery

  • No intervention
    control group

    At baseline, students in both the intervention and control groups will complete the Introductory Characteristics Data Collection Form, the Premenstrual Syndrome Scale, and the WHO Quality of Life Scale. No intervention will be applied to the control group; however, they will be asked to complete the Menstrual Cycle Follow-up Form throughout the study. After two menstrual cycles, both groups will again complete the Premenstrual Syndrome Scale and the WHO Quality of Life Scale.

Interventions

  • Behavioralguided imagery

    Guided imagery is a form of mind-body communication, defined as a flow of thoughts involving what we smell, taste, see, hear, and touch, or as the way the mind encodes, stores, and retrieves information. Guided imagery is based on the understanding that the mind and body are interconnected and that the mind can influence bodily functions. Stress and anxiety directly affect the brain and the immune system.

06

What researchers measure

Primary outcomes

  1. premenstrual syndrome

    The Premenstrual Syndrome Scale, developed by Gençdoğan (2006), is a five-point Likert-type instrument consisting of 44 items designed to assess the severity of premenstrual symptoms, based on DSM-III and DSM-IV-R criteria. In scoring, responses are rated as follows: "None" = 1 point, "Very little" = 2 points, "Sometimes" = 3 points, "Often" = 4 points, and "Always" = 5 points.

    Time frame: two months

07

Study locations

1 site
  • Başkent University
    Ankara, 06790, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it movedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from May 2026 to primary completion in Oct 2026, 5 months.

Of 76 non-industry interventional studies with no phase under Premenstrual Syndrome, half reached primary completion within 5 months of starting (the median), counting those still running; a quarter within 2 and three quarters within 12. This study's 5 months is close to that.

Counting every sponsor, half of 87 studies reached it within 5 months; a quarter within 3 and three quarters within 10.

Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 22, 2026: primary completion Sep 2026 → Oct 2026 and completion Dec 2026 → Oct 2026.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Sep 24, 2025
First posted
Oct 2, 2025
StartActual
May 15, 2026
Primary completionActual
Oct 19, 2026was Sep 2026
CompletionActual
Oct 19, 2026was Dec 2026
Last update
Oct 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Status
Recruiting→Completed
changed Oct 22, 2026
Primary completion
Sep 20, 2026→Oct 19, 2026 (actual)
Oct 22, 2026
Study completion
Dec 15, 2026→Oct 19, 2026 (actual)
Oct 22, 2026
Enrollment
48 (estimated)→61 (actual)
Oct 22, 2026
Show all 1 update
  1. Oct 22, 2026
    Recruiting→Completed
    Primary completion Sep 20, 2026→Oct 19, 2026 (now actual)
    Study completion Dec 15, 2026→Oct 19, 2026 (now actual)
    Enrollment 48 (estimated)→61 (actual)
    + 4 other changes: verification date, design details, contact details and site details

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07202650
Lead sponsor
Baskent University
Responsible party
Sponsor
First posted
Oct 2, 2025
Start date
May 15, 2026
Primary completion
Oct 19, 2026
Completion
Oct 19, 2026
Last update
Oct 22, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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