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RecruitingNCT07518134UV1Updated Nov 2, 2026

A Study of Uveitis in Children <18 Years of Age

An observational study in Uveitis, sponsored by Jaeb Center for Health Research. Recruiting at 4 sites in United States. Open to participants aged Up to 17 Years. Per ClinicalTrials.gov, last updated 2026-11-02.

Sponsored by Jaeb Center for Health Research · Observational

From the registry’s dates

  • Started Apr 2026; still recruiting 6 months later.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
300
Ages
Up to 17 Years
Sex
All
01

Study summary

The goal of this observational study is to collect data regarding clinical features and current/past treatments in children under 18 with uveitis. The main questions it aims to answer are:

  • What are the frequency of uveitis subtypes in children?
  • What are clinical and demographic characteristics overall and within each type of uveitis?

Participants will complete one enrollment visit with their doctor. Participants with uveitis onset \<6 months from enrollment date will also partake in a 12 month chart review.

02

Conditions studied

  • Uveitis

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Keywords

  • pediatric
  • uveitis
03

In context

Uveitis

299 studies on the registry are indexed under Uveitis; 32 are open to participants now.

This study's planned enrollment of 300 is above the median of 107 across 104 observational studies indexed under Uveitis.

Browse Uveitis studies →

Lead sponsor

Jaeb Center for Health Research is the lead sponsor of 129 studies on the registry; 16 are open to participants now.

Of its 17 completed or terminated interventional studies of FDA-regulated products, 15 (88%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Up to 17 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Children \<18 years with active or inactive uveitis.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age:

    • Incident cases (onset ≤ 6 months) \<17 years
    • Established cases (onset > 6 months) \<18 years
  • Diagnosis of any type of uveitis (infectious or noninfectious) in any location except traumatic and post-operative uveitis.
  • Active or inactive uveitis with any treatment status (current / prior / none [but under surveillance]).

Exclusion criteria

Exclusion Criteria:

  • Bilateral uveitis with differing etiologies
  • Traumatic uveitis
  • Post-operative uveitis
  • Immediate family member (spouse, biological or legal guardian, child, sibling, parent) who is an investigative site personnel directly affiliated with this study or who is an employee of JAEB Center for Health Research.
  • Ocular disease related to Retinoblastoma, Coat's disease, retinitis pigmentosa, inherited retinal degeneration, Juvenile xanthogranuloma (JXG), or leukemia/ within the eye.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
300 participants (estimated)
Target follow-up
12 Months
Patient registry
Yes

Groups and cohorts

  • Children diagnosed with uveitis - established cases

    Children diagnosed with uveitis (onset \> 6 months), either active or inactive with or without current treatment at time of enrollment.

  • Children diagnosed with uveitis - incident cases

    Children diagnosed with uveitis (onset ≤ 6 months), either active or inactive with or without current treatment at time of enrollment.

06

What researchers measure

Primary outcomes

  1. Frequency of uveitis subtypes in children <18 years of age

    Time frame: Enrollment

07

Study locations

4 of 4 sites recruiting
08

References and documents

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: Yes

Supporting information: Study protocol, Statistical analysis plan, Informed consent form

09

Updates

1 registry update since Sep 25, 2026
Minor edits
Nothing that changes what the study is or who can join. Edited: date precision
1 update, last Nov 2, 2026
Show all 1 update
  1. Nov 2, 2026
    Minor edits only
    + 1 other change: date precision

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07518134
Responsible party
Sponsor
First posted
Apr 8, 2026
Start date
Apr 14, 2026
Primary completion
Apr 1, 2027 (estimated)
Completion
Apr 1, 2028 (estimated)
Last update
Nov 2, 2026

Study contacts

Julianne Zawadzki, MSPH
Contact
jrobinson@jaeb.org
813-975-8690
Raymond Kraker, MSPH
Contact
rkraker@jaeb.org
8139758690
Kara C LaMattina, MD
study chair · Department of Ophthalmology, Boston University School of Medicine
Virginia Miraldi Utz, MD
study chair · Children's Hospital Medical Center, Cincinnati

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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