Evaluation Study of Medical-Social Collaboration Model for Middle-aged and Older Adults With Depressive Symptoms

Browse trials for

• Depression 8,057
• Psychological Well-Being 971

Keywords

• Depressive symptoms
• Mental health
• Medical-social collaboration
• Integrated health and social care
• Stepped-care intervention

Depression

8,057 studies on the registry are indexed under Depression; 1,641 are open to participants now.

This study's planned enrollment of 192 is above the median of 84 across 6,720 interventional studies indexed under Depression.

Lead sponsor

The University of Hong Kong is the lead sponsor of 1,262 studies on the registry; 340 are open to participants now.

Of its 8 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Study arms

• Experimental
  JC JoyAge stepped-care model

  Behavioral: Cognitive behavioural therapy-based stepped-care intervention

• Other
  Usual care with minimal support

  Other: Self-management booklet

Interventions

• BehavioralCognitive behavioural therapy-based stepped-care intervention

  After initial clinical assessment, participants will be offered interventions based on their depressive symptom severity (Patient Health Questionnaire-9-item \[PHQ-9\]). Mild symptoms (PHQ-9=5-9): 6 weekly low intensity CBT-based group intervention sessions led by trained clinical social workers, with 2 booster sessions as necessary. Moderate symptoms (PHQ-9=10-14): 6 weekly high intensity CBT-based group intervention sessions led by trained clinical social workers, with 2 booster sessions as necessary. Moderately severe symptoms (PHQ-9≥15): high intensity individual or group CBT-based intervention. Trained peer supporters will be matched to participants to walk them through the process with regular follow-up.

• OtherSelf-management booklet

  The booklet incorporates components of behavioural activation, which encourages participants to engage in meaningful activities in daily life to change their mood. Trained research assistants will regularly check in with the participants to monitor their depressive symptoms.

Primary outcomes

1. Changes in Depressive Symptoms

   Patient Health Questionnaire-9 (PHQ-9); range 0-27; higher scores indicate higher levels of depressive symptoms (worse outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

Secondary outcomes

1. Changes in Anxiety Symptoms

   Generalized Anxiety Disorder 2-item scale (GAD-2); range 0-6; higher scores indicate higher levels of anxiety symptoms (worse outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

2. Changes in Loneliness

   UCLA Loneliness Scale (UCLA-3); range 0-9; higher scores indicate higher levels of perceived loneliness (worse outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

3. Changes in Health Service Use

   Self-reported use of mental health services and medication in the past three months. Service data from Hospital Authority, covering information on outpatient visits, hospitalisation days, Accident and Emergency service utilisation, types of medications and operations, and any other major cost items that may be affected by depression with cost implications.

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

4. Changes in Health-Related Quality of Life

   EQ-5D-5L; range 0-1; higher scores indicate higher levels of health-related quality of life (better outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

Other outcomes

1. Self-Criticism and Self-Reassurance

   Short Form of Forms of Self-Criticizing/Attacking and Self-Reassuring Scale (FSCRS-SF); higher scores indicate a greater sense of inadequacy (score 0-20) (worse outcome), self-hate (score 0-16) (worse outcome), and self-reassurance (score 0-20) (better outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

2. Rumination

   Ruminative Response Scale - Brooding Subscale (RRS-Brooding); range 0-15; higher scores indicate higher frequency of depressive rumination (worse outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

3. Resilience

   Connor-Davidson Resilience Scale 2-Item (CD-RISC-2); range 0-8; higher scores indicate higher levels of resilience or better equipped to bounce back after stressful events (better outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

4. General Self-Efficacy

   Single-item General Self-Efficacy Scale (SI-DSES); range 1-5; higher scores indicate higher levels of self-efficacy (better outcome)

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

5. Stressful Events

   Self-reported stressful events, e.g. illness, death of close relative/friends.

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

6. Perceived Neighbourhood Environment

   Three items on participants' perceptions on their neighbourhood. First, whether participants think they have convenient access to leisure, shopping, community, and medical services and facilities. Second, whether participants think there are sufficient community events and opportunities to know their neighours. Third, whether participants think the neighbourhood is safe enough to walk around.

   Time frame: Baseline, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 21 months

Individual participant data

Plan to share: No — IPD will not be shared due to participant confidentiality reasons.