ClinicalTrials.gg
Enrolling by invitationNCT07038317Updated Oct 7, 2026

A Text Messaging Trial to Test Vaping Health Messages Optimized to Young Adults' Vaping Status

An interventional study of Intervention and Control in Vaping Behaviors, Message Exposure and Young Adults, sponsored by University of Hawaii. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years to 24 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-07.

Primary conditionVapingRegistry: BehaviorReclassifiedWhy we changed it
Registry
Behavior — the first condition term the registry derived for this study.
ClinicalTrials.gg
Vaping
Why
  1. The study's listed conditions name Vaping, a narrower term within Behavior.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by University of Hawaii · Not applicable, Interventional, and Prevention

Updated Oct 7, 2026Now Enrolling by invitationStart date movedGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
120
Allocation
Randomized
Ages
18 Years to 24 Years
Sex
All
01

Study summary

The goal of this study is to examine if e-cigarette education messages delivered using a source and presentation tailored to one's vaping status influences young adults' vaping behaviors. The main questions it aims to answer are:

  1. Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the current vaper group influence vaping cessation among young adults who vape daily?
  2. Does receiving e-cigarette education messages presented using a source (expert or peer) and sidedness (one or two-sided) optimized for the non-vaper group influence vaping initiation among young adults who are susceptible to vaping? Participants will be randomly assigned to either the treatment (receiving messages tailored to one's vaping status) or the control (receiving non-tobacco messages) condition and receive SMS three times per week over the course of 6 months. They will complete self-report assessment and show salivary cotinine results for nicotine testing at 4 timepoints.
02

Conditions studied

  • Vaping Behaviors
  • Message Exposure
  • Young Adults

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03

In context

Vaping Reclassified

402 studies on the registry are indexed under Vaping; 95 are open to participants now.

This study's planned enrollment of 120 is above the median of 79 across 322 interventional studies indexed under Vaping.

Browse Vaping studies →

Lead sponsor

University of Hawaii is the lead sponsor of 97 studies on the registry; 21 are open to participants now.

Of its 8 completed or terminated interventional studies of FDA-regulated products, 4 (50%) have results posted.

Compared within Vaping, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Behavior. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
18 Years to 24 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 18-24 years old
  • Fluent in English
  • Not currently using tobacco products other than e-cigarettes at the time of enrollment
  • Have a mobile phone to send and receive text messages

Exclusion criteria

Exclusion Criteria:

  • Age below 18 or above 24
  • Not being fluent in English
  • Currently using tobacco products other than e-cigarettes
  • Not having a mobile phone
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
120 participants (estimated)

Study arms

  • Experimental
    Treatment

    Participants in the treatment arm will receive e-cigarette education messages with source and sidedness optimized to one's vaping status.

    Other: Intervention

  • Placebo comparator
    Control

    Participants in the control arm will receive messages about sun safety.

    Other: Control

Interventions

  • OtherIntervention

    Intervention involves e-cigarette education messages tailored to participants' vaping status that will be sent out in SMS via text messaging three times per week over the course of 6 months.

  • OtherControl

    Participants will receive non-tobacco messages (messages about sun safety) three times per week over the course of 6 months.

06

What researchers measure

Primary outcomes

  1. Self-reported vaping

    Past-30-day vaping (yes/no) will be assessed

    Time frame: Baseline, six-month

  2. Biochemical confirmation of vaping

    Salivary cotinine for nicotine testing

    Time frame: Baseline, one-month, three-month, six-month

Secondary outcomes

  1. Harm perceptions

    Participants will be asked to indicate the extent to which they think vaping nicotine (using e-cigarettes) is… safe, containing flavors that are safe to use, containing dangerous chemical, harmful to health on a scale from 1 (strongly disagree) to 5 (strongly agree).

    Time frame: Baseline, one-month, three-month, six-month

  2. Message perceptions

    Participants will be asked to indicate the extent to which they think the message was worth remembering, grabbed their attention, powerful, convincing, meaningful on a scale from 1 (strongly disagree) to 5 (strongly agree).

    Time frame: One-month, three-month, six-month

  3. Message liking

    Participants will be asked to indicate the extent to which they liked the message they saw on a scale from 1 (dislike very much) to 5 (like very much).

    Time frame: One-month, three-month, six-month

  4. Number of days of past-30-day e-cigarette use

    Participants will be asked to report the number of days in the past 30 days (between 0 to 30) they used an e-cigarette.

    Time frame: From enrollment to the end of study at 24 weeks.

  5. E-cigarette accessibility

    Participants will be assessed how they usually purchase e-cigarettes for themselves with categorical response options of…in person, from the Internet, by phone, don't buy their own. This question will only be asked if response indicates participants are between the ages of 18 and 20 AND have used e-cigarettes more than 0 days in the past 30 days.

    Time frame: Baseline, one-month, three-month, six-month

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: Yes — De-identified participants dataset will be shared.

Supporting information: Study protocol, Informed consent form

Time frame: One year after the completion of study

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Status
Not yet recruiting→Enrolling by invitation
changed Oct 7, 2026
Start date
Jun 30, 2026→Jul 29, 2026 (actual)
Oct 7, 2026
Contact
No study contact listed any more: removed n•••@cc.hawaii.edu · •••8184
Oct 7, 2026
Show all 1 update
  1. Oct 7, 2026
    Not yet recruiting→Enrolling by invitation
    Start date Jun 30, 2026→Jul 29, 2026 (now actual)
    Contact No study contact listed any more: removed n•••@cc.hawaii.edu · •••8184
    + 2 other changes: identifiers and verification date

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07038317
Lead sponsor
University of Hawaii
Responsible party
Donghee Nicole Lee (Assistant Professor, University of Hawaii) — Principal investigator
First posted
Jun 26, 2025
Start date
Jul 29, 2026
Primary completion
Dec 30, 2027 (estimated)
Completion
Jan 31, 2028 (estimated)
Last update
Oct 7, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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