ClinicalTrials.gg
Sign In
CompletedNCT07022665Updated Jun 15, 2025

Influence of Hospital Volume on Mortality and Short-term Postoperative Outcomes in Uncomplex General Surgery in Switzerland

An observational study in Cholecystolithiasis, Cholecystitis and Inguinal Hernia, sponsored by Cantonal Hospital of St. Gallen. Completed at 1 site in Switzerland. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2025-06-15.

Sponsored by Cantonal Hospital of St. Gallen · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
399,701
Ages
20 Years and older
Sex
All
01

Study summary

The effect of centralisation measures on the operative outcomes after any type of surgery in Switzerland has not been highlighted yet. This study aims to investigate the influence of the annual case-specific hospital volume on uncomplex general surgery. The four operations investigated are appendectomy, cholecystectomy, umbilical hernia repair, and inguinal/femoral hernia repair.

02

Conditions studied

  • Cholecystolithiasis
  • Cholecystitis
  • Inguinal Hernia
  • Femoral Hernia
  • Umbilical Hernia
  • Appendicitis
03

In context

Cholecystolithiasis

88 studies on the registry are indexed under Cholecystolithiasis; 17 are open to participants now.

This study's enrollment of 399,701 is above the median of 341 across 28 observational studies indexed under Cholecystolithiasis.

Browse Cholecystolithiasis studies →

Lead sponsor

Cantonal Hospital of St. Gallen is the lead sponsor of 79 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

All patients with with appendicectomy for appendicitis, cholecystectomy for cholecystolithiasis and/or cholecystitis , umbilical hernia repair, or inguinal and/or femoral hernia repair operated in Switzerland between 2013 and 2022.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients with appendicectomy for appendicitis, cholecystectomy for cholecystolithiasis and/or cholecystitis , umbilical hernia repair, or inguinal and/or femoral hernia repair

Exclusion criteria

Exclusion Criteria:

  • incomplete case documentation
  • age under 20 years
  • other hospitals than general or surgical hospitals
  • no index operation
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
399,701 participants (actual)
Target follow-up
90 Days
Patient registry
Yes

Groups and cohorts

  • Appendicectomy

    Procedure: Appendicectomy

  • Cholecystectomy

    Procedure: Cholecystectomy

  • Umbilical hernia repair

    Procedure: Umbilical hernia repair

  • Inguinal and/or femoral hernia repair

    Procedure: Inguinal and/or femoral hernia repair

Interventions

  • ProcedureAppendicectomy

    Appendicectomy for appendicitis

  • ProcedureCholecystectomy

    Cholecystectomy for cholecystolithiasis and/or cholecystitis

  • ProcedureUmbilical hernia repair

    Any kind of umbilical hernia repair

  • ProcedureInguinal and/or femoral hernia repair

    Any kind of inguinal and/or femoral hernia repair

06

What researchers measure

Primary outcomes

  1. Mortality

    The association between the hospital volume and the postoperative mortality Mortality Yes or No Hospital volume as marginal effect Association with GAM logistic regression

    Time frame: Periprocedural

Secondary outcomes

  1. Reoperation

    The association between the hospital volume and the reoperation rate Reoperation Yes or No Hospital volume as marginal effect Association with GAM logistic regression

    Time frame: Periprocedural

  2. Length of hospital stay

    The association between the hospital volume and the length of hospital stay Length of hospital stay in days Hospital volume as marginal effect Association with quantile regression

    Time frame: Periprocedural

  3. Sociodemographic trends

    Time frame: 2013 - 2022

07

Study locations

1 site
  • HOCH Health Ostschweiz, Kantonsspital St.Gallen
    St.Gallen, 9000, Switzerland
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jan 2013 to primary completion in Dec 2022, 119 months.

How these figures are worked out, and which studies are left out of them.

Registered
May 26, 2025
First posted
Jun 15, 2025
StartActual
Jan 1, 2013
Primary completionActual
Dec 31, 2022
CompletionActual
Mar 1, 2023
Last update
Jun 15, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 15, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07022665
Lead sponsor
Cantonal Hospital of St. Gallen
Responsible party
Yanic Ammann (Principal Investigator, Cantonal Hospital of St. Gallen) — Principal investigator
First posted
Jun 15, 2025
Start date
Jan 1, 2013
Primary completion
Dec 31, 2022
Completion
Mar 1, 2023
Last update
Jun 15, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Cholecystolithiasis →

Other studies from this sponsor

Cantonal Hospital of St. Gallen

Start the discussion