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Not yet recruitingNCT06920017Updated Apr 9, 2025

Demographic Data and Clinical Presentation of Pediatric Uveitis

An observational study in Pediatric Uveitis, sponsored by Assiut University. Not yet recruiting. Open to participants aged Up to 18 Years. Per ClinicalTrials.gov, last updated 2025-04-09.

Sponsored by Assiut University · Observational

From the registry’s dates

  • Primary completion was expected by Apr 2026, 7 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
40
Ages
Up to 18 Years
Sex
All
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Study summary

To describe and analyze the demographics, Clinical characteristics, etiology, and visual outcomes of pediatric uveitis cases attending the outpatient clinic of Ophthalmology department, Assiut University Hospital.

Read the detailed description

Uveitis is a form of eye inflammation that affects the middle layer of tissue in the eye wall (uvea).

It is the third leading cause of blindness worldwide .Uveitis is more common in adults; however, children comprise 2.2% to 21.6% of patients in various studies.Despite a lower incidence of uveitis in children, the rate of visual loss may be worse than that of adults . The onset of uveitis in children is often insidious and is only discovered during routine screening.The lack of significant symptoms and delayed presentation to an ophthalmologist leads to morbidity and a decrease in visual acuity . The length of time between the diagnosis of uveitis and the referral to a tertiary eye center is strongly correlated with the complications rate and degree of visual impairment.

Uveitis is classified according to the International Uveitis Study Group criteria based on the anatomical location of the inflammation and is categorized as anterior, intermediate, Posterior or panuveitis. It is also described based on clinical onset, duration and course.

Some uveitis syndromes are unique to children, such as juvenile idiopathic arthritis (JIA), Kawasaki syndrome, Familial Juvenile Systemic Granulomatosis and Tubulointerstitial Nephritis-Uveitis syndrome. Other conditions are more prevalent in the pediatric population due to environmental factors such as trematode induced uveitis.

Due to the lack of epidemiological studies on the demographic and Clinical Characteristics of pediatric uveitis in Upper Egypt. This study aims to improve diagnosis, management, and treatment strategies tailored to the population.

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Conditions studied

  • Pediatric Uveitis

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03

In context

Uveitis

299 studies on the registry are indexed under Uveitis; 32 are open to participants now.

This study's planned enrollment of 40 is below the median of 107 across 104 observational studies indexed under Uveitis.

Browse Uveitis studies →

Lead sponsor

Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Up to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

pediatric patients

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Uveitis patients \<18 years old
  • must be able to participate in the study.

Exclusion criteria

Exclusion Criteria:

  • Age over 18 years.
  • Patients with post pentrating ocular trauma.
  • Patients whose legal guardians are unwilling to participate in the study.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
40 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Distribution of uveitis subtypes.

    Time frame: Baseline

  2. Differences by age, gender, or ethnicity.

    Time frame: Baseline

  3. Prevalence of systemic associations.

    Time frame: Baseline

  4. Prevalence of Visual outcomes.

    Time frame: Baseline

  5. Prevalence of complications rate.

    Time frame: Baseline

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • .Nussenblatt RB, Whitcup SM. Uveitis: Fundamentals and Clinical Practice, 4th edition. Mosby, 2010
  • Jabs DA, Nussenblatt RB, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. 2005 Sep;140(3):509-16. doi: 10.1016/j.ajo.2005.03.057. PubMed 16196117 ↗
  • American Academy of Ophthalmology meeting (Uveitis and Ocular Inflammation section), October 25, 2004; New Orleans, Louisiana
  • Rahimi M, Oustad M, Ashrafi A. Demographic and Clinical Features of Pediatric Uveitis at a Tertiary Referral Center in Iran. Middle East Afr J Ophthalmol. 2016 Jul-Sep;23(3):237-40. doi: 10.4103/0974-9233.186096. PubMed 27555706 ↗
  • Chan NS, Choi J, Cheung CMG. Pediatric Uveitis. Asia Pac J Ophthalmol (Phila). 2018 May-Jun;7(3):192-199. doi: 10.22608/APO.2018116. Epub 2018 Apr 23. PubMed 29682916 ↗
  • Cunningham ET Jr. Uveitis in children. Ocul Immunol Inflamm. 2000 Dec;8(4):251-61. doi: 10.1076/ocii.8.4.251.6459. PubMed 11262655 ↗
  • Rosenberg KD, Feuer WJ, Davis JL. Ocular complications of pediatric uveitis. Ophthalmology. 2004 Dec;111(12):2299-306. doi: 10.1016/j.ophtha.2004.06.014. PubMed 15582090 ↗
  • Edelsten C, Reddy MA, Stanford MR, Graham EM. Visual loss associated with pediatric uveitis in english primary and referral centers. Am J Ophthalmol. 2003 May;135(5):676-80. doi: 10.1016/s0002-9394(02)02148-7. PubMed 12719076 ↗
  • Azar D, Martin F. Paediatric uveitis: a Sydney clinic experience. Clin Exp Ophthalmol. 2004 Oct;32(5):468-71. doi: 10.1111/j.1442-9071.2004.00864.x. PubMed 15498056 ↗
  • Kump LI, Cervantes-Castaneda RA, Androudi SN, Foster CS. Analysis of pediatric uveitis cases at a tertiary referral center. Ophthalmology. 2005 Jul;112(7):1287-92. doi: 10.1016/j.ophtha.2005.01.044. PubMed 15921752 ↗
  • Benezra D, Cohen E, Maftzir G. Patterns of intraocular inflammation in children. Bull Soc Belge Ophtalmol. 2001;(279):35-8. PubMed 11344713 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 9, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06920017
Lead sponsor
Assiut University
Responsible party
Hasnaa Salah Ebrahim Abo Elyuon (Dr, Assiut University) — Principal investigator
First posted
Apr 9, 2025
Start date
Apr 1, 2025 (estimated)
Primary completion
Apr 2026 (estimated)
Completion
May 2026 (estimated)
Last update
Apr 9, 2025

Study contacts

Hasnaa Salah Ebrahim Abo Elyuon, master
Contact
Hassnaa.16266153@med.aun.edu.eg
+201090793398
Mohamed Sharaf El Din Abd El Rahim, professor
study director · Assiut University
Mohmed Gamal Ahmed Saleh, Assistant Professor
study director · Assiut University
Eslam Mohamed Mohamed Goda, Lecturer
study director · Assiut University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

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