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RecruitingNCT06899048Updated Mar 27, 2025

The Association Between Residual Neuromuscular Block Risk Prediction Score and the Train-of-Four Ratio

An observational study in Muscle Relaxants, sponsored by Assiut University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-03-27.

Sponsored by Assiut University · Observational

From the registry’s dates

  • Primary completion was expected by Oct 2025, 1 year ago, but the record still lists the study as recruiting.
  • Started Aug 2024; still recruiting 2 years 2 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
91
Ages
18 Years to 65 Years
Sex
All
01

Study summary

evaluate the degree of association, and the predictive accuracy of the REPS (as a predictive tool) compared with the TOFr as a quantitative assessment tool for (rNMB) in surgical patients in the early postoperative phase. The TOFr will be measured at 0, 15, 30, 45, and 60 min after extubation.

02

Conditions studied

  • Muscle Relaxants
03

In context

Muscle Hypotonia

64 studies on the registry are indexed under Muscle Hypotonia; 15 are open to participants now.

This study's planned enrollment of 91 is close to the median of 91 across 17 observational studies indexed under Muscle Hypotonia.

Browse Muscle Hypotonia studies →

Lead sponsor

Assiut University is the lead sponsor of 4,916 studies on the registry; 2,113 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients who will be scheduled to undergo elective surgical procedures requiring the use of neuromuscular blocking drugs.

Inclusion criteria

  1. Age group 18-65 years old
  2. Both genders
  3. Patients with American Society of Anesthesiologist physical status classification of 1 or 2.

Exclusion criteria

Exclusion Criteria:

  1. Patients who are less than 18 years old or more than 65 years old.
  2. Patients with planned scheduled recovery in the intensive care unit or if more than 10 minutes had elapsed since tracheal extubation until NMB monitoring at the PACU.
  3. Patients on medications that interfere with muscle activity.
  4. Known allergy to neuromuscular blocking agents.
  5. Pregnancy or suspected pregnancy.
  6. Neuro-muscular diseases.
  7. Patients refusing to participate in the study.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
91 participants (estimated)
Patient registry
No

Interventions

  • Diagnostic testresidual neuromuscular block risk prediction score

    it is a clinical tool designed to estimate the likelihood of residual neuromuxcular blockade in postoperative patients

06

What researchers measure

Primary outcomes

  1. correlation between residual neuromuscular block risk prediction score and train of four

    Time frame: 1 hour

07

Study locations

1 of 1 sites recruiting
  • Assiut University Hospitals
    Assiut, 71111, Egypt
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 27, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06899048
Lead sponsor
Assiut University
Responsible party
Mahmoud Faisal (Dr, Assiut University) — Principal investigator
First posted
Mar 27, 2025
Start date
Aug 1, 2024
Primary completion
Oct 1, 2025 (estimated)
Completion
Apr 1, 2026 (estimated)
Last update
Mar 27, 2025

Study contacts

Mahmoud A Faisal, Dr
Contact
dr_mahmoudfaisal@aun.edu.eg
01004391577 ext. 020

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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