ClinicalTrials.gg
Active, not recruitingNCT06822270Updated Feb 12, 2025

Different Surgical Modalities in the Management of Pelvi-ureteric Junction Obstruction

An interventional study of open surgery and Laparoscopic Pyeloplasty in Pelvi-ureteric Junction Obstruction, sponsored by Assiut University. Active, not recruiting at 1 site in Egypt. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2025-02-12.

Sponsored by Assiut University · Not applicable, Interventional, and Treatment

Help build ClinicalTrials.gg — short surveys, remote interviews or testing, in your language. Take part →

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

The study compared open pyeloplasty (OP) and laparoscopic pyeloplasty (LP) for treating Pelvi-ureteric Junction Obstruction (PUJO) in 40 patients.

02

Conditions studied

  • Pelvi-ureteric Junction Obstruction
03

In context

Multicystic renal dysplasia, bilateral

26 studies on the registry are indexed under Multicystic renal dysplasia, bilateral; 9 are open to participants now.

This study's enrollment of 40 is close to the median of 40 across 20 interventional studies indexed under Multicystic renal dysplasia, bilateral.

Browse Multicystic renal dysplasia, bilateral studies →

Lead sponsor

Assiut University is the lead sponsor of 5,081 studies on the registry; 2,179 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age between 7 months and 60 years. Diagnosed with Pelvi-ureteric Junction Obstruction (PUJO). (GFR) greater than 10 ml/min. Open to both genders.

Exclusion criteria

Exclusion Criteria:

  • Active infection. less than 10 ml/min. Presence of a single kidney. Patients with kidney or multiple congenital anomalies. Pregnancy.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

GFR and eGFR (kidney filtering)

GFR (glomerular filtration rate) is how much blood the kidneys filter each minute. It is usually estimated from a blood test — eGFR, by formulas such as CKD-EPI or MDRD — and some studies ask for it to be measured directly instead. Usually given in mL/min/1.73 m².

Check the method, the units and the minimum the study states. A value of 90 or above is in the normal-or-high range, but kidney damage can show in other tests too.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
40 participants (actual)

Study arms

  • Active comparator
    Open Pyeloplasty Group

    This group underwent traditional open surgical methods for treating Pelvi-ureteric Junction Obstruction.

    Procedure: open surgery

  • Experimental
    Laparoscopic Pyeloplasty Group (LP)

    This group was treated using minimally invasive laparoscopic techniques.

    Procedure: Laparoscopic Pyeloplasty

Interventions

  • Procedureopen surgery

    open surgical methods for treating Pelvi-ureteric Junction Obstruction

  • ProcedureLaparoscopic Pyeloplasty

    minimally invasive laparoscopic techniques.

06

What researchers measure

Primary outcomes

  1. Operative Success Rate

    evaluating the effectiveness of each surgical method in resolving PUJO

    Time frame: 3 days

07

Study locations

1 site
08

References and documents

Publications

  • Bar-Sever Z, Shammas A, Gheisari F, Vali R. Pediatric Nephro-Urology: Overview and Updates in Diuretic Renal Scans and Renal Cortical Scintigraphy. Semin Nucl Med. 2022 Jul;52(4):419-431. doi: 10.1053/j.semnuclmed.2021.12.002. Epub 2022 Jan 11. PubMed 35031115 ↗

Individual participant data

Plan to share: Undecided — Individual Participant Data (IPD) might not be shared due to privacy and confidentiality concerns. The ethical considerations mentioned in the study include informed consent obtained from patients regarding the surgery and data privacy. Sharing IPD could potentially compromise patient anonymity and expose sensitive personal health information, which must be protected under ethical research practices and relevant data protection regulations.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Oct 2024 to primary completion in Oct 2024, 0 months.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 28, 2024
First posted
Feb 12, 2025
StartActual
Oct 11, 2024
Primary completionActual
Oct 11, 2024
CompletionEst.
Dec 4, 2025
Last update
Feb 12, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Feb 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06822270
Lead sponsor
Assiut University
Responsible party
Mohamed Gamil Ahmed Saleh (Dr, Al-Azhar University) — Principal investigator
First posted
Feb 12, 2025
Start date
Oct 11, 2024
Primary completion
Oct 11, 2024
Completion
Dec 4, 2025 (estimated)
Last update
Feb 12, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion