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CompletedNCT06751693Updated Dec 30, 2024

Development of a Scoring and Prediction Model for Weaning Success in ARDS Patients Using Ventilation Parameters Combined with Artificial Intelligence and Deep Learning Techniques

An observational study in Deep Learning, Artificial Intelegence and ARDS (Acute Respiratory Distress Syndrome), sponsored by Bakirkoy Dr. Sadi Konuk Research and Training Hospital. Completed at 1 site in Turkey. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-12-30.

Sponsored by Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
25,000
Ages
18 Years and older
Sex
All
01

Study summary

This study aims to develop an AI-supported scoring model to optimize the weaning processes of ARDS patients from mechanical ventilation. Retrospective analysis will be conducted on the data of 25,000 patients, focusing on ventilator parameters and hemodynamic variables. The model will be designed to contribute to clinical decision support systems.

Read the detailed description

The aim of this study is to develop an artificial intelligence and deep learning-supported scoring system using ventilator parameters obtained during the mechanical ventilation process in patients diagnosed with ARDS. This system seeks to predict and optimize the weaning process, facilitating successful liberation from mechanical ventilation.

In this context, our study will analyze data from 25,000 patients obtained from the Metavision system. From this data pool, ARDS patients will be filtered and divided into two groups: those successfully weaned from mechanical ventilation (weaned) and those who were not (non-weaned). The ventilator parameters of both groups, including oxygenation indices, driving pressure, and total mechanical power, will be examined in detail.

The collected data will be analyzed using artificial intelligence and deep learning algorithms to develop a scoring system capable of predicting patients' weaning processes. This system is designed to guide clinicians in patient management and enhance the success of weaning procedures.

The results of this study aim to contribute to more efficient and safer management of the weaning process for ARDS patients. Furthermore, the implementation of AI-supported scoring systems in intensive care units is expected to promote widespread adoption and improve the quality of patient care.

02

Conditions studied

  • Deep Learning
  • Artificial Intelegence
  • ARDS (Acute Respiratory Distress Syndrome)

Keywords

  • Deep Learning
03

In context

Respiratory Distress Syndrome

1,597 studies on the registry are indexed under Respiratory Distress Syndrome; 312 are open to participants now.

This study's enrollment of 25,000 is above the median of 100 across 540 observational studies indexed under Respiratory Distress Syndrome.

Browse Respiratory Distress Syndrome studies →

Lead sponsor

Bakirkoy Dr. Sadi Konuk Research and Training Hospital is the lead sponsor of 118 studies on the registry; 14 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Intubated patients which diagnosed with ARDS and followed up in the ICU for more than 48 hours.

Inclusion criteria

  • ARDS diagnosis
  • Aged 18 years and older
  • Intubated and followed by Mechanical ventilation
  • Admission on Intensive care unit
  • Complete data on clinical support and desicion system

Exclusion criteria

Exclusion Criteria:

  • Missing data
  • Under 18 years of age
  • Followed by non-ARDS conditions
  • Terminal status
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
25,000 participants (actual)
Patient registry
No

Groups and cohorts

  • Weaned

    Those successfully weaned from mechanical ventilation

  • Non-weaned

    Those who not weaned from mechanical ventilation

06

What researchers measure

Primary outcomes

  1. Successful Weaning

    The primary outcome of this study will be the successful weaning from mechanical ventilation.

    Time frame: 48 hours

Secondary outcomes

  1. Mechanical Ventilatory Parameters

    Determining the impact of mechanical power on patient outcomes.

    Time frame: 48 hours

07

Study locations

1 site
  • Bakirkoy Dr Sadi Konuk Research and Training Hospital
    Istanbul, Turkey
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 30, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06751693
Lead sponsor
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Responsible party
Sponsor
First posted
Dec 30, 2024
Start date
Dec 10, 2024
Primary completion
Dec 24, 2024
Completion
Dec 24, 2024
Last update
Dec 30, 2024

Study contacts

Zafer Cukurova, M.D
study chair · Bakırkoy Dr. Sadi Konuk Training and Research Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.

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