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CompletedNCT06751368Updated Dec 27, 2024

The Fate of Aortic Valve After SAS Surgery in Children

An observational study in Subaortic Stenosis, Congenital Heart Disease and Aortic Regurgitation, sponsored by Chinese Academy of Medical Sciences, Fuwai Hospital. Completed at 1 site in China. Open to participants aged 0 Years to 18 Years. Per ClinicalTrials.gov, last updated 2024-12-27.

Sponsored by Chinese Academy of Medical Sciences, Fuwai Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
232
Ages
0 Years to 18 Years
Sex
All
01

Study summary

Aortic valve regurgitation (AR) is a common complication following surgery for subaortic stenosis (SAS), yet the long-term outcomes and risk factors for postoperative significant AR (SAR) remain poorly understood. This study aims to investigate the incidence and risk factors of SAR in SAS patients and evaluate the long-term postoperative outcomes.

02

Conditions studied

  • Subaortic Stenosis
  • Congenital Heart Disease
  • Aortic Regurgitation
03

In context

Heart Diseases

3,639 studies on the registry are indexed under Heart Diseases; 461 are open to participants now.

This study's enrollment of 232 is below the median of 294 across 1,241 observational studies indexed under Heart Diseases.

Browse Heart Diseases studies →

Lead sponsor

Chinese Academy of Medical Sciences, Fuwai Hospital is the lead sponsor of 141 studies on the registry; 48 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
0 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients age from 0-18 underwent SAS surgical repair at Fuwai Hospital.

Inclusion criteria

  • Age from 0-18
  • Clinical diagnosis of subaortic stenosis and underwent surgery

Exclusion criteria

Exclusion Criteria:

  • Diagnosed with hypertrophic cardiomyopathy
  • Underwent concomitant previous surgical repair for aortic valve or SAS
  • Follow-up time less than 1 year or lack of detailed information.
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
232 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Rate of Postoperative significant AR (SAR)

    Time frame: Through study completion, an average of 4 year

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Study locations

1 site
  • Fuwai Hospital
    Beijing, Beijing 100069, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 27, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06751368
Lead sponsor
Chinese Academy of Medical Sciences, Fuwai Hospital
Responsible party
Pan Xiangbin (Principal Investigator, Chinese Academy of Medical Sciences, Fuwai Hospital) — Principal investigator
First posted
Dec 27, 2024
Start date
Jan 1, 2008
Primary completion
Nov 30, 2024
Completion
Nov 30, 2024
Last update
Dec 27, 2024

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.

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