An observational study in Neurocognitive Disorder and Cardiac Surgery, sponsored by Chinese Academy of Medical Sciences, Fuwai Hospital. Not yet recruiting at 1 site in China. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2026-05-20.
Sponsored by Chinese Academy of Medical Sciences, Fuwai Hospital · Observational
Among 21 studies in Neurocognitive Disorders with a site in China — 12 open to participants now, 13 under way, 1 of them phase 3. Neurocognitive Disorders · China.
Among the 21 studies in Neurocognitive Disorders with a site in China, this one is one of 5 that started in 2026, is one of 6 observational ones, reaches primary completion later than 7 of the 12 other live ones, and was the 18th registered.
274 studies on the registry are indexed under Neurocognitive Disorders; 90 are open to participants now.
This study's planned enrollment of 210 is above the median of 150 across 96 observational studies indexed under Neurocognitive Disorders.
Browse Neurocognitive Disorders studies →12 of the 21 studies in Neurocognitive Disorders with a site in China are open now.
A study can be open while its sites in China have not opened yet or have stopped. Only those recruiting at a site in China →
Of the 59 Neurocognitive Disorders studies recruiting now, 36 (61%) set no upper age limit and 2 (3%) stop at 75 or younger; 4 take children under 18; 17 take healthy volunteers.
This study: 60 Years and older · all sexes · no healthy volunteers.
The full table on the hub →21 studies; the count open now beside each. This study's row is marked.
First in 2013; this study’s year is marked. 5 started in 2026.
Median enrollment 264 across the 15 interventional studies, 236 across the 6 observational. Of the 4 that completed or were terminated, 0 (0%) have results posted.
2 of 21 have an industry lead sponsor. The 10 most frequent:
Chinese Academy of Medical Sciences, Fuwai Hospital is the lead sponsor of 147 studies on the registry; 51 are open to participants now.
Chinese Academy of Medical Sciences, Fuwai Hospital has 3 studies filed under Neurocognitive Disorders — fewer than ten, so there is no comparison to draw.
6 of the studies in Neurocognitive Disorders with a site in China that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06416514Fujian Provincial HospitalPersonalized Interventions Via Health Portraits in Mild Behavioral Impairment | 2026-12-30 |
| NCT07878676Chinese Academy of Medical Sciences, Fuwai HospitalImpact of Preoperative Mild Cognitive Impairment on Postoperative Delirium in Patients Undergoing Cardiac Surgery | 2027-01 |
| NCT07665099Xijing HospitalThe Effect of Esketamine on Postoperative Cognitive Function in Elderly Patients Undergoing Oral and Maxillofacial Surgery | 2027-01-15 |
| NCT07914803Peking University First HospitalIntranasal Dexmedetomidine-esketamine Combination and Postoperative Cognitive Recovery in Older Patients | 2027-06 |
| NCT07048002Chinese Academy of Medical Sciences, Fuwai HospitalInterventions for Silent Brain Infarction and Perioperative Neurocognitive Disorders in Cardiovascular Surgery | 2027-10-31 |
Among the 21 studies in Neurocognitive Disorders with a site in China, from their registry updates:
The goal of this observational study is to explore the effect of remimazolam-based total intravenous anesthesia on postoperative neurocognitive function in patients who undergo cardiovascular surgery.
The main question this study tries to answer is: Does remimazolam influence the incidence of postoperative delirium in cardiovascular surgery? Participants already apply remimazolam-based total intravenous anesthesia as part of their regular medical treatment for general anesthesia to perform cardiac surgery will answer questionnaires about cognitive function after surgery.
Undergo elective cardiovascular surgery with cardiopulmonary bypass
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The study doctor’s estimate of how long someone is likely to live. Criteria use it so that people can stay in the study long enough for it to answer its question.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Life expectancy
The study doctor’s estimate of how long someone is likely to live. Criteria use it so that people can stay in the study long enough for it to answer its question.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
General anesthesia is remimazolam-based, combined with other intravenous agents.
General anesthesia is propofol-based, combined with other intravenous agents.
the 5-day incidence of postoperative delirium
the incedence of delirium evaluated by CAM/CAM-ICU
Time frame: within five days postoperatively
Time to extubation
Time to extubation postoperatively
Time frame: Perioperative
Length of stay (LOS) in intensive care unit (ICU)
Length of stay (LOS) in intensive care unit (ICU) postoperatively
Time frame: Perioperative
Length of stay (LOS) in hospital
Length of stay (LOS) in hospital postoperatively
Time frame: Perioperative
the 30-day composite incidence of major adverse events
Major adverse events refer to transient ischemic attack, stroke, renal insufficiency, myocardial infarction, pulmonary embolism, seizure and all-cause mortality.
Time frame: within 30 days postoperatively
Plan to share: No — Individual participant data (IPD) will not be shared in order to protect participant privacy and confidentiality. Additionally, the consent obtained from participants does not include provisions for data sharing, in accordance with ethical guidelines and institutional policies.
Start is estimated for Jun 2026; primary completion for Nov 2027, 17 months later.
Of 52 non-industry observational studies under Neurocognitive Disorders, half reached primary completion within 44 months of starting (the median), counting those still running; a quarter within 20 and three quarters within 78. This study's planned 17 months is below that.
Counting every sponsor, half of 53 studies reached it within 44 months; a quarter within 20 and three quarters within 78.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in May 2026. You cannot join it, but the record below documents what was studied.
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Chinese Academy of Medical Sciences, Fuwai Hospital →