An observational study in Autism Spectrum Disorder, Temporomandibular Joint Disorders and Postural; Defect, sponsored by Kırıkkale University. Recruiting at 1 site in Turkey. Open to participants aged 4 Years to 21 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-12-06.
Sponsored by Kırıkkale University · Observational
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Among 56 studies in Autism Spectrum Disorder with a site in Turkey — 11 open to participants now, 12 under way, none of them phase 3. Autism Spectrum Disorder · Turkey.
Among the 56 studies in Autism Spectrum Disorder with a site in Turkey, this one is the 9th largest by planned enrollment of the 10 observational ones that give a count, is one of 8 that started in 2024, is one of 10 observational ones, reaches primary completion later than 1 of the 11 other live ones, and was the 22nd registered.
1,727 studies on the registry are indexed under Autism Spectrum Disorder; 500 are open to participants now.
Browse Autism Spectrum Disorder studies →11 of the 56 studies in Autism Spectrum Disorder with a site in Turkey are open now. Recruiting first, the newest first:
Emre DANSUK · Sites in Turkey
Ages 3–9 · Healthy volunteers
Atlas University · Sites in Turkey
Ages 7–10
Özlem Teke · Sites in Turkey
Ages 0–12
Kırıkkale University · Sites in Turkey
Ages 4–21 · Healthy volunteers
Saglik Bilimleri Universitesi · Sites in Turkey
Ages 6–11
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 349 Autism Spectrum Disorder studies recruiting now, 48 (14%) set no upper age limit and 294 (84%) stop at 75 or younger; 298 take children under 18; 92 take healthy volunteers.
This study: 4 Years to 21 Years · all sexes · healthy volunteers too.
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56 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 8 started in 2024.
This study's planned enrollment of 23 is below the median of 102 across 321 observational studies indexed under Autism Spectrum Disorder.
Median enrollment 35 across the 46 interventional studies, 74 across the 10 observational. Of the 44 that completed or were terminated, 0 (0%) have results posted.
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None of the 56 has an industry lead sponsor. The 10 most frequent:
Kırıkkale University is the lead sponsor of 114 studies on the registry; 24 are open to participants now.
Kırıkkale University has 2 studies filed under Autism Spectrum Disorder — fewer than ten, so there is no comparison to draw.
3 of the studies in Autism Spectrum Disorder with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07751679Marmara UniversityLEGO-Based Play Therapy for Children With Autism Spectrum Disorder | 2026-11 |
| NCT07789704Emre DANSUKStructured Sensory-Based Occupational Therapy in Children With Autism | 2027-01-01 |
| NCT07739693Fenerbahce UniversityEffects of Hippotherapy in Children With Autism Spectrum Disorder | 2027-03 |
Add all 3 to your calendar (.ics) → With an account.
Among the 56 studies in Autism Spectrum Disorder with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The aim of our study is to evaluate temporomandibular joint (TMJ), cervical posture, balance, dual-task performance, and social adaptation skills in individuals with autism. The study will be conducted at Bartın Lider Special Education and Rehabilitation Center following the approval of the ethics committee. Individuals determined by the sample size calculated through power analysis will be included in the study. First, the socio-demographic characteristics (age, height, body weight, body mass index, education level, exercise and smoking habits, etc.) of the participants who voluntarily join the study will be recorded. Participants will be divided into two groups: individuals with typical motor development and those with autism spectrum disorder (ASD), and the same assessment tools will be used for both groups. Individuals with typical motor development will serve as the control group.
The assessment tools include the Timed Up and Go (TUG) test, the 10-Meter Walk Test, the Vineland Adaptive Behavior Scale, the PostureScreen Android-based posture assessment application, and the Helkimo Clinical Dysfunction Index for craniomandibular disorders. Based on the evaluation results, the relationships between TMJ, cervical posture, functional balance, dual-task performance, and social adaptation skills in individuals with autism will be analyzed and compared with those of individuals with typical motor development.
It has been stated in the literature that individuals with autism spectrum disorder have postural control deficiency, but there is no study examining the dual task skills of these individuals and the contribution of these skills to social life.
It has been stated in the literature that bruxism can cause TMJ in individuals with normal development, and there are studies related to TMJ's cervical problems and balance. However, there are no studies explaining the relationship between teeth grinding and dental problems in individuals with ASD, temporomandibular joint problems and cervical posture and balance.
Studies suggest that multi-faceted evaluations be made in individuals with ASD. The aim of our study is to evaluate TMJ dysfunction, cervical posture, functional balance, dual task and social adaptation skills in individuals with ASD. In terms of these evaluations, our study has the feature of a pilot study in the literature.
The assessments will be conducted at the Physical Therapy Unit of the Lider Special Education and Rehabilitation Center, where voluntary families will be contacted and evaluations will be carried out within the rehabilitation center.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Other: Dual Task · Other: Functional Balance · Other: Social Adaptation Assessment · Other: Cervical Posture Assessment: · Other: Temporomandibular Joint (TMJ) Assessment
Other: Dual Task · Other: Functional Balance · Other: Social Adaptation Assessment · Other: Cervical Posture Assessment: · Other: Temporomandibular Joint (TMJ) Assessment
The dual-task abilities of individuals will be assessed by adding motor and cognitive tasks to the 10-Meter Walk Test. The tasks given to participants are as follows: Single Motor Task (comfortable walking): The individual is asked to walk at a normal pace, and the time is recorded. Motor-Motor Dual Task: The individual carries a half-filled water bottle in each hand while walking, and the time is recorded. Motor-Cognitive Dual Task (mental): The individual counts backward from 10 in increments of one while walking, and the time is recorded. Motor-Cognitive Dual Task (memory): The individual is asked to recall three previously mentioned words while walking, and the time is recorded.
Functional balance will be assessed using the Timed Up and Go (TUG) test. The TUG test measures the time it takes for an individual to stand up from a chair upon the "ready, go" signal, walk a distance of 3 meters, turn around, walk back to the chair, and sit down again. The TUG test is a reliable and sensitive measure of balance and functional mobility in children. At the beginning of the test, participants will be seated on an armless chair with their hips and knees flexed at approximately 90 degrees and their feet flat on the ground. The children will be instructed to stand up from the chair, walk as quickly as possible, touch a target on the wall, walk back, and sit down again.
Adaptive behavior will be evaluated using the Vineland Adaptive Behavior Scales. This is a parent interview designed to assess functionality in daily life. Specifically, adaptive behavior is evaluated in four domains: Communication, Daily Living Skills, Socialization, and Motor Skills. The Vineland scales are known for their reliability and up-to-date validity. They have been reported to be sensitive to the challenges faced by children with Autism Spectrum Disorder (ASD).
Cervical posture will be evaluated using the Android-based PostureScreen Mobile application (version 8.5, developed by Posture Co. Inc., USA). This application assesses the static posture of individuals. After determining reference points, the application draws reference lines and records postural deviations. At least two photos of each participant will be taken for the assessment. Participants should not wear clothing items that cover the neck (e.g., scarves, shawls). While the primary focus of the application is to assess postural deviations, it also includes a dental evaluation feature. The validity and reliability of the application have been established in previous studies. In addition to using the application, the posture of individuals will also be evaluated through observational analysis, and the findings will be documented.
The TMJ will be evaluated using the Helkimo Clinical Craniomandibular Index. This index consists of five subcategories: pain during muscle palpation, pain during TMJ palpation, pain during mandibular functions, TMJ functions (sounds, gliding during maximum opening, dislocation and/or locking), and the mandibular range of motion. Each subcategory is scored as 0, 1, or 5, resulting in a total score ranging from 0 to 25. As this index is based on performance measurements, there is no Turkish validity and reliability study for it. However, a prevalence study using this index was conducted in Turkey by Üner et al. to evaluate its applicability within the Turkish population.
Cervical Posture Assessment
Android-based PostureScreen Mobile (version 8.5, developed by Posture CO.inc. USA) application will be used for cervical posture assessment. The application evaluates the static posture of individuals
Time frame: At enrollment
Temporomandibular Joint (TMJ) Assessment:
Helkimo Clinical Craniomandibular Index will be used for TMJ evaluation. This index consists of 5 subsections: pain on muscle palpation, pain on TMJ palpation, pain in mandibular functions, TMJ functions (sound, gliding at maximum extension, luxation and/or locking) and the capacity of mandibular movement.
Time frame: At enrollment
Social Adaptation Assessment:
Adaptive behavior will be assessed with the Vineland Adaptive Behavior Scales. It is a parent interview designed to assess functioning in daily life.
Time frame: At enrollment
Functional Balance
It will be assessed with the TUG test. The TUG ready measures the time it takes for an individual to get up from a chair, walk a distance of 3 meters, turn around, walk back to the chair and sit down again after the start signal.
Time frame: At enrollment
Plan to share: Yes
No publications or documents are linked to this record.
Started Feb 2024 (actual). Primary completion is estimated for Jan 2025, 10 months after the start.
Of 98 non-industry observational studies under Autism Spectrum Disorder, half reached primary completion within 47 months of starting (the median), counting those still running; a quarter within 27 and three quarters within 120. This study's planned 10 months is below that.
Counting every sponsor, half of 112 studies reached it within 40 months; a quarter within 26 and three quarters within 120.
How these figures are worked out, and which studies are left out of them.
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