An interventional study of HIIT only and HIIT & Record of physical activities at home. in Head and Neck Cancer and Skeletal Muscle, sponsored by Chang Gung Memorial Hospital. Recruiting at 1 site in Taiwan. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by Chang Gung Memorial Hospital · Not applicable, Interventional, and Other
Among 22 studies in Head and Neck Neoplasms by Chang Gung Memorial Hospital — 7 open to participants now, 7 under way, none of them phase 3. Head and Neck Neoplasms · Chang Gung Memorial Hospital.
Among the 22 studies in Head and Neck Neoplasms by Chang Gung Memorial Hospital, this one is one of 2 that started in 2023, is one of 7 with no phase, and was the 19th registered.
2,710 studies on the registry are indexed under Head and Neck Neoplasms; 594 are open to participants now.
This study's planned enrollment of 280 is above the median of 46 across 2,032 interventional studies indexed under Head and Neck Neoplasms.
Browse Head and Neck Neoplasms studies →7 of the 22 studies in Head and Neck Neoplasms by Chang Gung Memorial Hospital are open now, in 1 country. Each count lists the studies.
Of the 453 Head and Neck Neoplasms studies recruiting now, 345 (76%) set no upper age limit and 51 (11%) stop at 75 or younger; 21 take children under 18; 27 take healthy volunteers.
This study: 20 Years to 80 Years · all sexes · no healthy volunteers.
The full table on the hub →22 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 2 started in 2023.
Median enrollment 92 across the 9 interventional studies, 150 across the 13 observational. Of the 9 that completed or were terminated, 0 (0%) have results posted.
Chang Gung Memorial Hospital is the lead sponsor of 1,096 studies on the registry; 239 are open to participants now.
1 of the studies in Head and Neck Neoplasms by Chang Gung Memorial Hospital that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06666881Chang Gung Memorial HospitalSkeletal Muscle Mass Changes on Images for Prediction of Prognosis After Exercise Training in HNSCC Patients | 2027-09-30 |
Among the 22 studies in Head and Neck Neoplasms by Chang Gung Memorial Hospital, from their registry updates:
Nothing recorded among them since 2026-09-25.
This project adopts a prospective study design. It is scheduled to enroll 60 participants diagnosed with Head and Neck cancer in this hospital, of which 30 are in the experimental group and 30 are in the control group. The purpose of this research is to analyze the skeletal muscle mass changes on images in Head and Neck cancer patients after exercise training and the association with systemic inflammatory markers. Investigators would like to know whether these images and biomarkers predict the prognosis of Head and Neck cancer. Subjects enrolled in the trial will receive 36 times of exercise training after concurrent chemoradiotherapy. Before and after the completion of exercise training, investigators will arrange (1) dual energy X-ray absorptiometry (DXA) to measure the whole-body skeletal muscle mass and appendicular skeletal muscle mass and (2) blood tests for markers of systemic inflammation. In addition to DXA, computed tomography (CT) is another image modality for skeletal muscle mass evaluation. Positron emission tomography - CT or whole-body CT for cancer staging are considered as baseline studies. The routine follow-up CT images are used to analyze the changes after exercise training. If magnetic resonance imaging is also performed during the follow-up period, images will also be collected and assessed as an alternative.If the experimental group can maintain or even improve skeletal muscle mass and can be reflected in blood tests and prognosis, the result may be able to apply on cancer treatment and disease followup.
This project adopts a prospective study design. It is scheduled to enroll 60 patients diagnosed with Head and Neck cancer in this hospital, of which 30 are in the experimental group and 30 are in the control group. The purpose of this research is to analyze the skeletal muscle mass changes on images in Head and Neck cancer participants after exercise training and the association with systemic inflammatory markers. Investigators would like to know whether these images and biomarkers predict the prognosis of head and neck cancer. Subjects enrolled in the trial will receive 36 times of exercise training after concurrent chemoradiotherapy. Before and after the completion of exercise training, investigators will arrange (1) dual energy X-ray absorptiometry (DXA) to measure the whole-body skeletal muscle mass and appendicular skeletal muscle mass and (2) blood tests for markers of systemic inflammation. In addition to DXA, computed tomography (CT) is another image modality for skeletal muscle mass evaluation. Positron emission tomography - CT or whole-body CT for cancer staging are considered as baseline studies. The routine follow-up CT images are used to analyze the changes after exercise training. If magnetic resonance imaging is also performed during the follow-up period, images will also be collected and assessed as an alternative. If the experimental group can maintain or even improve skeletal muscle mass and can be reflected in blood tests and prognosis, the result may be able to apply on cancer treatment and disease follow-up.
This project can determine the baseline skeletal muscle mass of Head and Neck cancer patients and hope to monitor its changes after exercise training through imaging tools and find the most suitable imaging modalities. To understand the role of systemic inflammatory markers in sarcopenia, exercise training and oral cancer prognosis. This study hopes to serve as a basis and reference for clinical treatment selection, imaging follow up, interventional treatment or rehabilitation. The results of this research should benefit participants in Taiwan and abroad, and to promote the medical treatment and health of participants.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A scale of how much an illness limits everyday activity. For people being assessed to join a study, scores run from 0 (fully active) to 4; lower is more active.
Studies most often ask for 0–1 or 0–2. Your doctor gives the score; the WHO scale uses the same steps. The full scale also has 5, which records death.
ECOG performance status
A scale of how much an illness limits everyday activity. For people being assessed to join a study, scores run from 0 (fully active) to 4; lower is more active.
Studies most often ask for 0–1 or 0–2. Your doctor gives the score; the WHO scale uses the same steps. The full scale also has 5, which records death.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
No Intervention: Head and Neck patients after CCRT treatment. After CCRT treatment, participants keep follow the skeletal muscle mass evaluation
Experimental: Head and Neck patients after CCRT treatment with exercise training. After CCRT treatment 4-5 week, arrange participants do the exercise training for patient. Two to three times a week ,total 24-36 times. Participants keep follow the skeletal muscle mass evaluation.
Other: HIIT only · Other: HIIT & Record of physical activities at home.
After CCRT treatment 4-5 week, arrange participants do the HIIT exercise for two to three times a week and total 24-36 times.
After CCRT treatment 4-5 week, arrange participants do the HIIT exercise for two to three times in a week and total 24-36 times. And do the recording of physical activities at home.
dual energy X-ray absorptiometry data
measure the whole-body skeletal muscle mass
Time frame: baseline,pre-iprocedure
dual energy X-ray absorptiometry data
measure the whole-body skeletal muscle mass
Time frame: 3 month, during procedure
dual energy X-ray absorptiometry data
measure the whole-body skeletal muscle mass
Time frame: 8 month, during procedure
dual energy X-ray absorptiometry data
measure the whole-body skeletal muscle mass
Time frame: 11 month, during procedure
Cardiopulmnary Exercise Test
record the VO2% of participants by doing the exercise test to assess the cardiopulmnary funtion before and after excercise training
Time frame: baseline,pre-iprocedure
Cardiopulmnary Exercise Test
record the VO2% of participants by doing the exercise test to assess the cardiopulmnary funtion before and after excercise training
Time frame: 3 month, during procedure
Cardiopulmnary Exercise Test
record the VO2% of participants by doing the exercise test to assess the cardiopulmnary funtion before and after excercise training
Time frame: 8 month, during procedure
Cardiopulmnary Exercise Test
record the VO2% of participants by doing the exercise test to assess the cardiopulmnary funtion before and after excercise training
Time frame: 11 month, during procedure
computed tomography (CT)
check toumor condition and another image modality for skeletal muscle mass evaluation
Time frame: baseline,pre-iprocedure
computed tomography (CT)
check toumor condition and another image modality for skeletal muscle mass evaluation
Time frame: 8 month, during procedure
blood data-myostatin
inflammatory markers
Time frame: 3 month, during procedure
blood data-myostatin
inflammatory markers
Time frame: 8 month, during procedure
blood data-IL-10
inflammatory markers
Time frame: 3 month, during procedure
blood data-IL-10
inflammatory markers
Time frame: 8 month, during procedure
blood data-IL-1β
inflammatory markers
Time frame: 3 month, during procedure
blood data-IL-1β
inflammatory markers
Time frame: 8 month, during procedure
blood data-IL-15
inflammatory markers
Time frame: 3 month, during procedure
blood data-IL-15
inflammatory markers
Time frame: 8 month, during procedure
Plan to share: No
Started Jun 2023 (actual). Primary completion is estimated for Sep 2027, 51 months after the start.
Of 437 non-industry interventional studies with no phase under Head and Neck Neoplasms, half reached primary completion within 33 months of starting (the median), counting those still running; a quarter within 18 and three quarters within 71. This study's planned 51 months is above that.
Counting every sponsor, half of 455 studies reached it within 32 months; a quarter within 18 and three quarters within 70.
How these figures are worked out, and which studies are left out of them.
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