An interventional study of Whole-Body Vibration and Control Condition in Knee Osteoarthristis, sponsored by University of Erlangen-Nürnberg Medical School. Completed at 1 site in Germany. Open to participants aged 40 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-02-03.
Sponsored by University of Erlangen-Nürnberg Medical School · Not applicable, Interventional, and Treatment
Knee osteoarthritis is a chronic joint disease with an impact on quality of life and an increasing incidence what leads to huge costs and burden on the economy.
The present study investigates immediate effects of whole-body vibration on pain, neuromuscular performance, and gait quality in patients with knee osteoarthritis. Eligible patients (n=20) with knee osteoarthritis grade 2 or 3 on Kallgren Lawrence will complete a 5 minute WBV training and a control condition in a randomized order (cross over design). Pain, maximum strength of the leg flexors and extensors, the chair rise test and gait parameters will be measured directly before and after the intervention/control.
4,398 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.
This study's enrollment of 20 is below the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.
Browse Osteoarthritis studies →University of Erlangen-Nürnberg Medical School is the lead sponsor of 267 studies on the registry; 51 are open to participants now.
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Exclusion Criteria:
The intervention (IC) will be specified as a five-minute Whole-Body Vibration session.
Other: Whole-Body Vibration
The control condition (CC) will conduct the same protocol as the intervention condition. The only difference will be that the vibration plate will be switched off.
Other: Control Condition
The intervention (IC) will be specified as a five-minute Whole-Body Vibration session. The WBV take place on a side alternating vibration plate (Wellengang, Germany). The patients stand barefoot on the vibration plate on a prescribed position. In this position the amplitude will be 6-7mm. The WBV protocol contains mobilizing sequences with lower frequencies and activating sequences with higher frequencies
Non-intervention control condition
Changes in pain of the osteo-arthrotic knee
Changes in pain of the osteo-arthrotic knee during the treadmill test as determined on a visual analogue scale (VAS 0-10).
Time frame: Changes in pain of the osteoarthrotic knee during the treadmill test as determined on a visual analogue scale (VAS 0-10) before and after 5 min of intervention
Changes in isometric maximum leg flexion strength of the osteoarthritis knee
Changes in isometric maximum leg flexion strength of the osteoarthritis knee as determined by dynamometer (easy torque, Tonus, Germany)
Time frame: Changes in isometric maximum leg flexion strength of the osteoarthritis knee before and after 5 min of Intervention.
Changes in isometric maximum leg extension strength of the osteoarthritis knee
Changes in isometric maximum leg extension strength of the osteoarthritis knee as determined by dynamometer (easy torque, Tonus, Germany)
Time frame: Changes in isometric maximum leg extension strength of the osteoarthritis knee before and after 5 min of Intervention
Changes of number of repetitions in the 30 s sit to stand (chair rise) test
Changes in number of repetitions in the 30 s sit-to-stand test as suggested by Guralnik et al.
Time frame: Changes in number of repetitions in the 30 s sit-to-stand test before and after 5 min of intervention
Changes of ipsilateral stride length
Changes of ipsilateral stride length (cm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of ipsilateral stride length (cm) at treadmill as determined by the 4D motion high-performance lab ( (Firma Diers Formetric, Germany) before and after 5 min of Intervention
Changes of ipsilateral stride time
Changes of ipsilateral stride length (cm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of ipsilateral stride length (cm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention.
Changes of stride width
Changes of stride width (cm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of stride width (cm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention.
Changes of ipsilateral stance time
Changes of ipsilateral stance time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of ipsilateral stance time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention
Changes of ipsilateral single support time
Changes of ipsilateral single support time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of ipsilateral single support time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention
Changes of double support time
Changes of double support time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of double support time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention
Changes of trunk inclination
Changes of trunk inclination (mm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of trunk inclination (mm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention
Changes of ipsilateral und kontralateral knee angle in frontal plane
Changes of ipsilateral und kontralateral knee angle (°) in frontal plane at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of ipsilateral und kontralateral knee angle (°) in frontal plane at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention
Changes of ipsilateral und kontralateral knee angle in sagital plane
Changes of ipsilateral und kontralateral knee angle in sagital plane (°) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany)
Time frame: Changes of ipsilateral und kontralateral knee angle in sagital plane (°) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention
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University of Erlangen-Nürnberg Medical School