An observational study in Calcaneal Spur, sponsored by University of Erlangen-Nürnberg Medical School. Recruiting at 1 site in Germany. Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2026-07-31.
Sponsored by University of Erlangen-Nürnberg Medical School · Observational
The clinical picture of calcaneal spur with plantar fasciitis is a debilitating disease that is difficult to treat with conservative and interventional measures. Radiotherapy has shown very good therapeutic results in retrospective data, which need to be clinically confirmed both subjectively and in terms of image morphology in a prospective approach.
Primary objective of the study:
To demonstrate a clinical benefit of LDRT: improvement of pain, functionality and quality of life after LDRT
32 studies on the registry are indexed under Heel Spur; 10 are open to participants now.
Browse Heel Spur studies →University of Erlangen-Nürnberg Medical School is the lead sponsor of 276 studies on the registry; 52 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with heel spurs experience pain and inflammation, as do those with plantar fasciitis, which often goes hand in hand with it.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A 0–100 scale of how well someone can carry out everyday activities. 100 is no complaints and no signs of illness; 70 is able to look after yourself but not to work or keep up normal activity; 50 is needing considerable help and frequent medical care.
Studies often ask for 60 or 70 and above. Your doctor gives the score.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Karnofsky performance status (KPS)
A 0–100 scale of how well someone can carry out everyday activities. 100 is no complaints and no signs of illness; 70 is able to look after yourself but not to work or keep up normal activity; 50 is needing considerable help and frequent medical care.
Studies often ask for 60 or 70 and above. Your doctor gives the score.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Childbearing potential
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraception
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Radiotherapy with a guideline-compliant (Radiotherapy of benign diseases; specialist group-specific evidence-based S2e guideline of the German Society for Radio-Oncology (DEGRO)) single dose of 0.5 Gy (3.0 Gy total dose) over 3 weeks and, if pain persists, a second series with the same dosage at 12-week intervals.
Procedure: Low-dose Radiation Therapy (LDRT) using MRI-based imaging techniques
LDRT using MRI-based imaging techniques by developing an MRI imaging protocol, deep learning-based image enhancement and resolution increase.
Proof of clinical benefit of LDRT using pain scale
Visual analog scale: pain scale from 0-10 (0..no pain - 10..worst pain)
Time frame: 36 months
Proof of clinical benefit of LDRT using QoL
QoL: SF-8 (Short Form-8 Health Survey), scale from 0-100 (0..worst score - 100..best score)
Time frame: 36 months
Proof of clinical benefit of LDRT using Calcaneodynia score
Calcaneodynia score, scale from 0-100 (0..worst performance - 100..best performance)
Time frame: 36 months
Proof of clinical benefit of LDRT using AOFAS Hindfoot Scale
AOFAS Hindfoot Scale, Score ranges from 0 to 100, with healthy ankles receiving 100 points.
Time frame: 36 months
Proof of clinical benefit of LDRT using Roles and Maudsley Scale
Roles and Maudsley scale is a 4-point subjective assessment used to evaluate patient pain and limitations in daily activities following treatment. It ranges from 1 (excellent result, no symptoms) to 4 (poor result, symptoms identical or worse than before treatment).
Time frame: 36 months
Proof of an objectifiable clinical benefit of LDRT using MRI-based imaging techniques by developing an MRI imaging protocol
Time frame: 36 months
Correlation of subjective pain parameters with laboratory chemical examinations.
Time frame: 36 months
Correlation of subjective pain parameters, gait analyses and tendon elasticity with inflammatory components in the patient serum.
Time frame: 36 months
Correlation of immune cell subpopulations with disease severity by correlating them with MRI and laboratory findings.
Time frame: 36 months
Plan to share: No
No publications or documents are linked to this record.
Started Jun 2026 (actual). Primary completion is estimated for Apr 2027, 10 months after the start.
How these figures are worked out, and which studies are left out of them.
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University of Erlangen-Nürnberg Medical School →