An interventional study of exercise in Renal Dialysis, sponsored by Yunfeng Xia. Recruiting at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2024-08-23.
Sponsored by Yunfeng Xia · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to discuss the effects of physical activity on nutrition, inflammation, muscle metabolism, and the occurrence of cardiovascular and cerebrovascular events in patients with maintenance haemodialysis. The main question it aims to answer is: can exercise improve nutritional and inflammatory status, enhance muscle strength, and reduce the incidence of cardiovascular and cerebrovascular events in patients with maintenance haemodialysis.
Researchers will compared active exercise group to conventional treatment group to see the impact of exercise on maintenance haemodialysis patients.
Participants will:
Choose low-intensity aerobic exercise workouts such as walking (no less than 8,000 steps per day) or jogging, swimming, Tai Chi, etc., according to their individual conditions, for no less than 30 minutes at a time, at least 3 times per week, and the intensity of the exercise should be based on an RPE score of 12 to 16.
RPE: Rating of Perceived Exertion. RPE scores of 12 to 16 indicate the need for increased respiratory rate and depth during exercise, the ability to engage in conversational exchanges, light sweating, and a feeling of slight fatigue without reaching a state of exhaustion.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
This study's planned enrollment of 200 is above the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Browse Motor Activity studies →Yunfeng Xia is the lead sponsor of 4 studies on the registry; 3 are open to participants now.
Compared within Motor Activity, the registry's first condition term, which may not be this study's main condition. Counted across the registry records on this site, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
patients were asked to choose walking (no less than 8000 steps per day) or low-intensity aerobic exercise such as jogging, swimming, Tai Chi, etc., according to their own conditions, for no less than 30 minutes each time, at least 3 times per week, and the intensity of the exercise was determined by the need to increase the frequency and depth of breathing during the exercise, and it was appropriate to feel slightly tired but not exhausted (RPE score 12-16). Exercise intensity should be at least 3 times a week, and the exercise intensity should be at a level that requires an increase in breathing rate and depth, allowing for dialogue and communication, slight sweating, and a feeling of being slightly tired but not exhausted (RPE score of 12 to 16).
Behavioral: exercise
only receive conventional MHD treatment, no requirement for exercise.
such as walking, jogging, swimming, Tai Chi, etc. It needs to be at a certain frequency and intensity
Mid-upper arm circumference of the non-internal fistula side（AC）
Measure the circumference of the non-internal fistula at the midpoint of the upper arm using a soft tape measure, in centimetres
Time frame: Baseline and half year, 1 year
triceps skin-fold thickness of the non-internal fistula side（TSF）
Measurement of the skinfold at the midpoint of the upper arm on the non-internal fistula side by using a skinfold thickness gauge, in centimetres
Time frame: Baseline and half year, 1 year
upper arm muscle circumference of the non-internal fistula side（AMC）
AMC（cm）= AC(cm) - 3.14 x TSF（cm）
Time frame: Baseline and half year, 1 year
calf circumference
Measure the calf circumference using a soft tape measure, in centimetres
Time frame: Baseline and half year, 1 year
grip strength
Using a grip strength meter, with the patient seated and gripping the handle firmly with the palm of the non-internal fistulae side, measure twice and record the maximum grip strength value
Time frame: Baseline and half year, 1 year
Incidence of cardiovascular and cerebrovascular events
Cardiovascular events include: heart failure episodes, sustained arrhythmias, myocardial infarction, and cerebrovascular events include: cerebral haemorrhage, cerebral infarction, transient ischaemic attack.
Time frame: 1 year
prealbumin
laboratory measurement indicators:prealbumin(g/L)
Time frame: Baseline and half year, 1 year
albumin
laboratory measurement indicators:albumin(g/L)
Time frame: Baseline and half year, 1 year
haemoglobin
laboratory measurement indicators:haemoglobin(g/L)
Time frame: Baseline and half year, 1 year
blood lipids
laboratory measurement indicators:triglycerides, cholesterol, low-density lipoprotein, high-density lipoprotein
Time frame: Baseline and half year, 1 year
c-reactive protein
laboratory measurement indicators:c-reactive protein(mg/L)
Time frame: Baseline and half year, 1 year
Plan to share: No
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Yunfeng Xia