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RecruitingNCT07291154Updated Dec 18, 2025

Impact of APP-assisted Patient Management on the Quality Control of Blood Purification Therapy

An interventional study of APP-based management in End Stage Renal Disease (ESRD) and Maintenance Hemodialysis, sponsored by Yunfeng Xia. Recruiting at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-12-18.

Sponsored by Yunfeng Xia · Not applicable, Interventional, and Health services research

Phase
Not applicable
Study type
Interventional
Enrollment
392
Allocation
Randomized
Ages
18 Years to 75 Years
Sex
All
01

Study summary

Many maintenance hemodialysis (MHD) patients develop negative outlooks due to their illnesses and complications, making their quality of life and prognosis a clinical concern. Effective life management and treatment cooperation are crucial to improving dialysis quality and patient outcomes. This trial aims to evaluate whether management through the "Yueya" mini-program and WeChat can provide personalized guidance such as health education, diet, exercise, medication supervision, and condition monitoring to enhance treatment compliance, quality of life, strengthen quality control in the hemodialysis unit, and improve patient prognosis.

Patients will be divided into a group receiving support via the "Yueya" mini-program and WeChat, and a control group receiving routine care. Clinical and laboratory indicators, cardiovascular events, death, hospitalization, quality of life, and compliance will be recorded and compared between groups to assess the impact of APP-assisted patient management on the quality of MHD blood purification therapy and the prognosis of MHD patients.

Read the detailed description

Affected by their own diseases and various complications, many maintenance hemodialysis (MHD) patients have a negative and pessimistic attitude toward life. Their quality of life and prognosis have always been a concern for clinicians. Therefore, how to adjust and manage the lives of these patients, enable them to actively cooperate with various treatment methods, maximize the quality of blood purification therapy, and improve their quality of life and prognosis has become an extremely important research topic.

02

Conditions studied

  • End Stage Renal Disease (ESRD)
  • Maintenance Hemodialysis
03

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients with stage 5 chronic kidney disease, who have received maintenance hemodialysis for more than 3 months, are aged between 18 and 75 years old, and have regular dialysis three times a week.
  • Patients with relatively stable condition, who are able to take care of themselves and willing to cooperate with the study.
  • Patients who can understand and proficiently use WeChat and the "Yueya" mini - program used in this study.

Exclusion criteria

Exclusion Criteria:

  • Patients with communication barriers or other conditions that prevent them from cooperating with the study.
  • Patients who have a history of acute myocardial infarction, cerebral infarction or intracerebral hemorrhage in the past six months.
  • Patients who are not willing to actively cooperate with the study.
  • Patients with severe liver cirrhosis, active tuberculosis and AIDS.
04

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
392 participants (estimated)

Study arms

  • Experimental
    APP management group

    For the APP management group, according to the specific conditions of patients such as age, gender, primary disease and complications, the "Yueya" mini-program and WeChat will be used to provide individualized and all-weather guidance for dialysis patients in their daily lives, including health knowledge education, diet and exercise guidance, medication supervision, condition monitoring and real-time feedback.

    Behavioral: APP-based management

  • No intervention
    Non-APP management group

    For the non-APP management group, the APP mini-program will not be used to guide patients' daily lives, and only the previous routine management methods will be adopted.

Interventions

  • BehavioralAPP-based management

    Based on patients' specific conditions such as age, gender, primary disease, and complications, the APP-based management will provide individualized and round-the-clock guidance for dialysis patients in their daily lives through the "Yueya" mini-program and WeChat. This guidance covers various aspects, including health knowledge education, diet and exercise guidance, medication supervision, condition monitoring, and real-time feedback.

05

What researchers measure

Primary outcomes

  1. mortality rate

    In this study, mortality rate was used as a prognostic indicator.

    Time frame: About 1 year

  2. Hospitalization rate

    In this study, the hospitalization rate was used as a prognostic indicator.

    Time frame: About 1 year

  3. Kidney Disease Quality of Life

    Measuring the quality of life of hemodialysis patients through the Kidney Disease Quality of Life-36(KDQOL-36) scale. If the KDQOL-36 score increases, the quality of life is considered to be improved.

    Time frame: About 1 year

  4. Incidence of cardiovascular events

    Time frame: About 1 year

06

Study locations

1 of 1 sites recruiting
  • The First Affiliated Hospital of Chongqing Medical University
    Chongqing, Chongqing Municipality 400016, China
    Recruiting
07

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07291154
Lead sponsor
Yunfeng Xia
Responsible party
Yunfeng Xia (Cheif physician, First Affiliated Hospital of Chongqing Medical University) — Sponsor-investigator
First posted
Dec 18, 2025
Start date
Sep 22, 2025
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Dec 18, 2025

Study contacts

Yunfeng Xia Dr
Contact
yunfengxia0920@126.com
86-023-89012687

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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