CClinicalTrials.gg
Not yet recruitingNCT06510712Updated Jul 19, 2024

Nutritional Risk for Hospitalized Patients With Neurology Disorders in China

An observational study in Neurological Disorder, sponsored by Xuanwu Hospital, Beijing. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-07-19.

Sponsored by Xuanwu Hospital, Beijing · Observational

From the registry’s dates

  • Primary completion was expected by Jun 2026, 4 months ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
10,000
Ages
18 Years and older
Sex
All
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Study summary

Neurology disorders are one of the major public health problems that seriously threaten human health. It often accompanied by various nutritional problems, which can aggravate the primary disease, lead to serious complications, prolong the hospitalization, lead to poor prognosis, and increase family and social economic burdens. According to the previous studies, the risk of malnutrition was approximately 58.5% of stroke patients, and 6% had moderate to severe malnutrition in China. Another study conducted in Beijing showed that the risk of malnutrition of elderly patients in the department of neurology was significantly higher than in other departments (28.5% vs. 26.4%). Strengthening nutritional supervision of patients with neurology disorders will benefit to improve patients' prognosis. Therefore, the aim of this study is to investigate the nutritional status of inpatients with neurology disorders in China, evaluate the impact of different nutritional status on patients' health outcomes, and establish a high-quality, standardized nutrition and health cohort database for neurology disorders.

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Conditions studied

  • Neurological Disorder

Keywords

  • nutrition
  • the risk of malnutrition
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In context

Nervous System Diseases

974 studies on the registry are indexed under Nervous System Diseases; 252 are open to participants now.

This study's planned enrollment of 10,000 is above the median of 127 across 318 observational studies indexed under Nervous System Diseases.

Browse Nervous System Diseases studies →

Lead sponsor

Xuanwu Hospital, Beijing is the lead sponsor of 346 studies on the registry; 217 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Participants with the primary diagnosis are neurological disoders

Inclusion criteria

  1. Age ≥ 18 years;
  2. The primary diagnosis was neurological disorders;
  3. Written informed consent.

Exclusion criteria

Exclusion Criteria:

  1. Life expectancy is \< 3 months;
  2. Researchers think other ineligible participant for the study.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
10,000 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. All-cause mortality

    Mortality defined as all-cause mortality from inclusion to day 30

    Time frame: 30 days

Secondary outcomes

  1. ICU admission

    ICU admission defined as admission to the intensive care unit from the medical ward from inclusion to day 30

    Time frame: 30 days

  2. Non-elective hospital readmission

    Non-elective hospital readmission defined as non-scheduled hospital readmission after discharge from the index hospital stay to day 30

    Time frame: 30 days

  3. Major complications

    Major complications defined as the following complications occurring from inclusion (i.e., not present at the time of inclusion) to day 30 I. Adjudicated nosocomial infection or abscess requiring antibiotic treatment II. respiratory failure with need for invasive or non-invasive ventilation III. major cardiovascular events including stroke, intracranial bleeding, cardiac arrest, myocardial infarction with and without invasive procedure and pulmonary embolism IV. acute renal failure (defined by 2x increase of baseline creatinine or new requirement of dialysis do to volume overload or electrolyte disturbance) V. gastro-intestinal events (hemorrhage, intestinal perforation)

    Time frame: 30 days

  4. Decline in functional status of 10% or more

    decline in functional status of 10% or more from admission to day 30 measured by the Barthel's index.

    Time frame: 30 days

  5. length of in hospital days

    Total length of in hospital days 30 days

    Time frame: 30 days

Other outcomes

  1. Adverse events

    Each of the adverse events

    Time frame: 30 days

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021 Oct;20(10):795-820. doi: 10.1016/S1474-4422(21)00252-0. Epub 2021 Sep 3. PubMed 34487721 ↗
  • Wang YJ, Li ZX, Gu HQ, Zhai Y, Jiang Y, Zhao XQ, Wang YL, Yang X, Wang CJ, Meng X, Li H, Liu LP, Jing J, Wu J, Xu AD, Dong Q, Wang D, Zhao JZ; China Stroke Statistics 2019 Writing Committee. China Stroke Statistics 2019: A Report From the National Center for Healthcare Quality Management in Neurological Diseases, China National Clinical Research Center for Neurological Diseases, the Chinese Stroke Association, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention and Institute for Global Neuroscience and Stroke Collaborations. Stroke Vasc Neurol. 2020 Sep;5(3):211-239. doi: 10.1136/svn-2020-000457. Epub 2020 Aug 21. PubMed 32826385 ↗
  • Brenton JN, Lehner-Gulotta D, Woolbright E, Banwell B, Bergqvist AGC, Chen S, Coleman R, Conaway M, Goldman MD. Phase II study of ketogenic diets in relapsing multiple sclerosis: safety, tolerability and potential clinical benefits. J Neurol Neurosurg Psychiatry. 2022 Jun;93(6):637-644. doi: 10.1136/jnnp-2022-329074. Epub 2022 Apr 13. PubMed 35418509 ↗
  • FOOD Trial Collaboration. Poor nutritional status on admission predicts poor outcomes after stroke: observational data from the FOOD trial. Stroke. 2003 Jun;34(6):1450-6. doi: 10.1161/01.STR.0000074037.49197.8C. Epub 2003 May 15. PubMed 12750536 ↗
  • Mehta A, De Paola L, Pana TA, Carter B, Soiza RL, Kafri MW, Potter JF, Mamas MA, Myint PK. The relationship between nutritional status at the time of stroke on adverse outcomes: a systematic review and meta-analysis of prospective cohort studies. Nutr Rev. 2022 Nov 7;80(12):2275-2287. doi: 10.1093/nutrit/nuac034. PubMed 35640017 ↗

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06510712
Lead sponsor
Xuanwu Hospital, Beijing
Responsible party
Sponsor
First posted
Jul 19, 2024
Start date
Sep 1, 2024 (estimated)
Primary completion
Jun 1, 2026 (estimated)
Completion
Jun 30, 2026 (estimated)
Last update
Jul 19, 2024

Study contacts

Gaoting Ma, PhD
Contact
demo_doctor@163.com
18301579891
Junwei Hao, PhD
principal investigator · Capital Medical University Xuanwu Hospital

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.

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