An interventional study of single exercise bout about one-leg exercise in Exercise, sponsored by Hacettepe University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2025-12-04.
Sponsored by Hacettepe University · Not applicable, Interventional, and Supportive care
COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and muscle oxygenation are observed in COPD. One leg exercise result is not enough to highlight these parameters.
Acute Effects of Three Different Types Single Leg Exercise in Copd
single bout high intensity interval training
single bout continuous exercise training single bout resistance training
2,426 studies on the registry are indexed under Motor Activity; 1,161 are open to participants now.
This study's enrollment of 26 is below the median of 60 across 2,118 interventional studies indexed under Motor Activity.
Browse Motor Activity studies →Hacettepe University is the lead sponsor of 983 studies on the registry; 212 are open to participants now.
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Exclusion Criteria:
first session: single session leg Continuous exercise intervantion will be applied to COPD. Unilaterally single leg continuous exercise will be performed as only one session second session : single session leg high intensity interval exercise intervantion will be applied to COPD. Unilaterally single leg hııt exercise will be performed as only one session third sessionsingle session leg resistance exercise intervantion will be applied to COPD. Respirocally leg strength (knee extantion ) exercise will be performed
Other: single exercise bout about one-leg exercise
cycle exercise includes single leg
six minute walk test
six minute walk test in meter
Time frame: beginning, day 1
cardiopulmonary exercise test
VO2 max will be recorded as ml/kg/min will be recorded from incremental cycle cpet test
Time frame: beginning, day 2
single leg extremity test
VO2 max will be recorded as ml/kg/min will be recorded from incremental cycle cpet test
Time frame: beginning, day 3
lung function
FVC in % , FEV1 in %, FEV1/FVC ratio, PEF in % and FEF 25-75 in %
Time frame: beginning, day 1
muscle strength (isometric)
quadriceps isometric muscle strength will be recorded as kilogram
Time frame: beginning day 1
muscle strength (10 repeated max)
quadriceps 10 repeated max muscle strength will be recorded as kilogram
Time frame: beginning, day 1
continous exercise acute (single leg)
VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session
Time frame: beginning day 4
high intensity interval training acute exercise (single leg)
VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session
Time frame: beginning day 5
strength training acute exercise (single leg)
VO2 max will be recorded as ml/kg/min will be performed from incremental cycle exercise at single session
Time frame: beginning day 4,5,6
muscle oxygenation
minumum muscle oxygenation level will be presented as percentage
Time frame: beginning day 4,5,6
arterial stifness
Aıx@75 in %
Time frame: beginning day 2,3, 4,5,6
This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.
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Hacettepe University