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CompletedNCT06462846Updated Jun 17, 2024

Evaluation of Clinical Characteristics and Pathological Findings in Patients With Suspected Appendicitis

An observational study in Appendicitis, sponsored by Golestan University of Medical sciences. Completed at 1 site in Iran, Islamic Republic of. Per ClinicalTrials.gov, last updated 2024-06-17.

Sponsored by Golestan University of Medical sciences · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
291
Sex
All
01

Study summary

As we know, one of the most common reasons for people to visit health centers and hospitals (15%) is abdominal pain, and appendicitis is at the top of their diagnosis in the 2-4th decade of age, which in most cases For treatment, considering the patient's condition and the need for surgery, appendectomy is the first method. One of the things that helps us a lot in this area is the epidemiology and incidence of this disease in the target society, which sometimes varies in different regions. One of the things that can be checked in this disease is the age and gender of the person and its incidence in different age ranges.

Read the detailed description

appendicitis is one of the most important reasons for people to go to the hospital, and 15% of the visits to the hospital are for this reason, and sometimes patients end up undergoing appendectomy. The mortality rate of this disease is 0.2-1% among young people and 8% among people over 65 years old In some people, depending on the sex, age, pregnancy and related diseases and even the weight of the people, the location of the appendix is different and this issue is very important during surgery. Different positions of the appendix, such as retro-scapular, subhepatic, pelvic, etc., create different challenges during surgery, so investigating the possibilities of the location of the appendix is an important issue in the decision-making and preparation of the patient and the surgical team.

Also, laboratory criteria such as wbc, diff, plt, crp can also help in diagnosing this disease. In this project, in addition to the above, the chief complaints and accompanying symptoms of people have also been examined

02

Conditions studied

  • Appendicitis

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Keywords

  • Appendicitis
  • Appendectomy
  • Appendicitis diagnosis
03

In context

Appendicitis

419 studies on the registry are indexed under Appendicitis; 67 are open to participants now.

This study's enrollment of 291 is above the median of 200 across 151 observational studies indexed under Appendicitis.

Browse Appendicitis studies →

Lead sponsor

Golestan University of Medical sciences is the lead sponsor of 9 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patents operated with the diagnosis of appendicitis in 5th azar medical center, in 2022

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • diagnosis of appendicitis
  • appendectomy

Exclusion criteria

Exclusion Criteria:

  • Lack of required information in medical documents
05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
291 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. The accuracy of imaging in determining the size of the appendix in patients with suspected appendicitis

    comparison of the appendix size reported in radiologic studies with pathologic findings

    Time frame: One year

Secondary outcomes

  1. correlation between CRP levels and pathologic findings in patients with suspected appendicitis

    Comparison of CRP levels in the different stages of appendicitis according to pathologic reports

    Time frame: One year

  2. correlation between WBC measures and pathologic findings in patients with suspected appendicitis

    Comparison of WBC measures in the different stages of appendicitis according to pathologic reports

    Time frame: One year

  3. sex distribution in patients with suspected appendicitis

    the prevalence and percentage of each sex group in patients with suspected appendicitis

    Time frame: one year

  4. Age distribution in patients with suspected appendicitis

    the prevalence and percentage of each age group in patients with suspected appendicitis

    Time frame: one year

  5. prevalence of clinical findings in patients with suspected appendicitis

    prevalence and percentage of each clinical finding (fever, anorexia, shifting pain, tenderness, rebound tenderness, rovsing sign, psoas sign) in patients with suspected appendicitis

    Time frame: one year

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Study locations

1 site
  • Golestan University of Medical Sciences, faculty of medicine
    Gorgan, Golestan 4918936316, Iran, Islamic Republic of
08

References and documents

Publications

  • Lee JH, Park YS, Choi JS. The epidemiology of appendicitis and appendectomy in South Korea: national registry data. J Epidemiol. 2010;20(2):97-105. doi: 10.2188/jea.je20090011. Epub 2009 Dec 19. PubMed 20023368 ↗
  • Golz RA, Flum DR, Sanchez SE, Liu X, Donovan C, Drake FT. Geographic Association Between Incidence of Acute Appendicitis and Socioeconomic Status. JAMA Surg. 2020 Apr 1;155(4):330-338. doi: 10.1001/jamasurg.2019.6030. PubMed 32129808 ↗
  • Tavra A, Quien D, Barcot O. Oncological aspect of incidental appendectomy with regard to histopathological findings: A retrospective cohort study. Eur J Surg Oncol. 2023 Oct;49(10):107013. doi: 10.1016/j.ejso.2023.107013. Epub 2023 Aug 11. PubMed 37597285 ↗
  • Yagmur Y, Sogutcu N, Gumus S. Recent classifications systems for gastroenteropancreatic neuroendocrine tumors A single-center experience. Ann Ital Chir. 2020;91:598-604. PubMed 32989209 ↗
  • Bayhan Z, Yildiz YA, Akdeniz Y, Gonullu E, Altintoprak F, Mantoglu B, Capoglu R, Kahyaoglu Akkaya Z. Appendix Neuroendocrine Tumor: Retrospective Analysis of 4026 Appendectomy Patients in a Single Center. Emerg Med Int. 2020 Sep 3;2020:4030527. doi: 10.1155/2020/4030527. eCollection 2020. PubMed 32963833 ↗
  • Henriksen SR, Rosenberg J, Fonnes S. Other Pathologies Were Rarely Reported after Laparoscopic Surgery for Suspected Appendicitis: A Systematic Review and Meta-Analysis. Dig Surg. 2023;40(3-4):91-99. doi: 10.1159/000531283. Epub 2023 Jul 18. PubMed 37463567 ↗
  • Jukic M, Nizeteo P, Matas J, Pogorelic Z. Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study. Children (Basel). 2023 May 15;10(5):887. doi: 10.3390/children10050887. PubMed 37238435 ↗
  • Pineda Villeda RH, Flores Reyes DL, Suazo Rivera JF. Acute Appendicitis: Epidemiological, Clinical, Surgical, and Post-surgical Characteristics in a Honduran General Hospital. Cureus. 2023 Jun 14;15(6):e40428. doi: 10.7759/cureus.40428. eCollection 2023 Jun. PubMed 37456484 ↗

Individual participant data

Plan to share: Undecided

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Apr 2022 to primary completion in May 2024, 25 months.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 1, 2024
First posted
Jun 17, 2024
StartActual
Apr 19, 2022
Primary completionActual
May 20, 2024
CompletionActual
May 30, 2024
Last update
Jun 17, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 17, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06462846
Lead sponsor
Golestan University of Medical sciences
Responsible party
ronak jalali (Medical student, Golestan University of Medical sciences) — Principal investigator
First posted
Jun 17, 2024
Start date
Apr 19, 2022
Primary completion
May 20, 2024
Completion
May 30, 2024
Last update
Jun 17, 2024

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.

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