An observational study in Vascular Access Complication, sponsored by Golestan University of Medical sciences. Completed at 1 site in Iran, Islamic Republic of. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-03-11.
Sponsored by Golestan University of Medical sciences · Observational
Arterio-Venous Fistula (AVF) is the most recommended vascular access for hemodialysis. Steal syndrome is a potential complication of AVF implantation and occurs secondary to diversion of the arterial flow of a limb to the venous system resulting in limb ischemia. Measuring wrist pressure compared to arm pressure before and after fistula implantation can be a suitable tool in predicting the possibility of Steal syndrome. In this study, the ratio of wrist to arm pressure and its relationship with Steal syndrome symptoms before and after fistula implantation are investigated.
Chronic kidney disease (CKD) affects the structure and function of the kidneys. Many of CKD patients are not suitable candidates for a kidney transplant, so relying on some type of dyalisis is unavoidable.
Hemodialysis is the most common type of Renal Replacement Therapy. The best vascular access for hemodialysis in patients with chronic renal failure is Arterio-venous fistula (AVF). One of the complications of arterio-venous fistula is Steal syndrome which is ischemia of the limb secondary to blood flow diversion from the arterial system to the venous system through AVF.
Non-invasive wrist blood pressure measurement before and after the fistula construction may accurately assess the risk of ischemia and Steal syndrome from a functional AVF. Wrist-brachial index as a reliable prognostic test could be done easily in time of fistula construction and if it is normal, it assures the surgeon that the distal circulation is sufficient.
Summary of the project implementation method: First, the demographic questionnaire is completed for patients who meet the criteria for entering the study. Then the wrist-brachial index of patients who are candidates for fistula implantation before and after the fistula implantation is measured. Two weeks and three months later (times of suture removal and fistula maturation assessment), the measurements are repeated and their correlations with steal syndrome symptoms are recorded.
The data will be analyzed in SPSS16 statistical software
247 studies on the registry are indexed under Arteriovenous Fistula; 44 are open to participants now.
This study's enrollment of 78 is below the median of 100 across 70 observational studies indexed under Arteriovenous Fistula.
Browse Arteriovenous Fistula studies →Golestan University of Medical sciences is the lead sponsor of 9 studies on the registry; 2 are open to participants now.
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All ESRD patients who are candidates for AVF implantation after arterial and venous mapping, cardiac evaluation, and informed consent.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The share of blood the heart’s main pumping chamber (the left ventricle) pushes out with each beat, measured by an echocardiogram (heart ultrasound) or a MUGA scan. About 50–70% is normal.
LVEF (left ventricular ejection fraction)
The share of blood the heart’s main pumping chamber (the left ventricle) pushes out with each beat, measured by an echocardiogram (heart ultrasound) or a MUGA scan. About 50–70% is normal.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Early post operative WBI changes following AVF implantation
Comparison of wrist-brachial index before and after implantation of AVF in the operating room
Time frame: one year
Two-week post operative WBI changes following AVF implantation
Comparison of wrist-brachial index before and two-week after implantation of AVF.
Time frame: one year
Three-month post operative WBI changes following AVF implantation
Comparison of wrist-brachial index before and three-month after implantation of AVF.
Time frame: one year
Correlation between WBI changes following AVF implantation with age
Comparison of WBI changes following AVF implantation in age sub groups
Time frame: one year
Correlation between WBI changes following AVF implantation with sex
Comparison of WBI changes following AVF implantation in sex sub groups
Time frame: one year
Correlation between WBI changes following AVF implantation with co-morbidities
Comparison of WBI changes following AVF implantation in co-morbidity sub groups
Time frame: one year
Correlation between WBI changes following AVF implantation with steal syndrome
comparison of WBI changes following AVF implantation between patients experiencing steal syndrome symptoms and Asymptomatic participants.
Time frame: one year
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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Golestan University of Medical sciences