An interventional study of Transmagnetic stimulation and TMS in Depressive Disorder, sponsored by Mansoura University. Not yet recruiting at 1 site in Egypt. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-05-21.
Sponsored by Mansoura University · Not applicable, Interventional, and Treatment
The goal of this interventional study is to learn if accelerated Intermittent Theta Burst Stimulation can improve symptoms of 30 participants with Unipolar depression in higher manner than symptoms of 30 participants with bipolar depression
We will apply stimulatory TMS protocol for participants with Unipolar depression and participants with bipolar depression using MagVenture MagPro R30 stimulator with the Cool-B65 coil
4,845 studies on the registry are indexed under Depressive Disorder; 514 are open to participants now.
This study's planned enrollment of 60 is below the median of 80 across 3,999 interventional studies indexed under Depressive Disorder.
Browse Depressive Disorder studies →Mansoura University is the lead sponsor of 1,077 studies on the registry; 183 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants with Unipolar depression will receive 30 sessions of TMS.10 sessions a week for 3 weeks
Device: Transmagnetic stimulation · Device: TMS
Participants with bipolar depression will receive 30 sessions of TMS.10 sessions a week for 3 weeks
Device: Transmagnetic stimulation · Device: TMS
Stimulatory TMS protocol using MagVenture MagPro R30 stimulator with the Cool-B65 coil
Stimulatory TMS protocol using MagVenture MagPro R30 stimulator with the Cool-B65 coil
Comparison of severity of manic symptoms before and after treatment
We will use Young Mania Rating Scale._Young Mania Rating Scale:assess severity of manic symptoms, clinician rated,\<=12(remission)13_19(minimal symptoms)20_25(mild mania)26_37(moderate mania)38_60 severe mania
Time frame: One year for completion of the study
Comparison of the severity of the patient's illness at the time of assessment relative to the clinician's past experience with patients who have the same diagnosis.
We will use Clinical Global Impression Severity Scale._Clinical Global Impression Severity Scale:rate the severity of the patient's illness at the time of assessment relative to the clinician's past experience with patients who have the same diagnosis,1 normal not at all ill,2 borderline mentally ill,3 mildly ill,4 moderately ill,5 markedly ill,6 severely ill,7 extremely ill
Time frame: One year for completion of the study
Comparison of severity and impact of insomnia before and after treatment
We will use Insomnia Severity Index scale._Insomnia Severity Index:assess the nature, severity and impact of insomnia,0_7(absence insomnia) 8_14(subthreshold insomnia)15_21(moderate insomnia)22_28(severe insomnia)
Time frame: One year for completion of the study
Comparison of depressive symptoms before and after treatment
We will use Hamilton Depression Rating Scale._Hamilton Depression Rating Scale:assess the severity of depressive symptoms, clinician rated,0_7(normal range)8_16(mild severity)17_23(moderate severity)\>23(severe depression)
Time frame: One year for completion of the study
Plan to share: No
This study is not yet recruiting, as verified in May 2024. You cannot join it, but the record below documents what was studied.
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Mansoura University