An observational study in Premature Ovarian Insufficiency, Bone Diseases, Metabolic and Bone Mineral Density, sponsored by Shi Yun. Recruiting at 1 site in China. Open to female participants aged 18 Years to 39 Years. Per ClinicalTrials.gov, last updated 2024-06-25.
Sponsored by Shi Yun · Observational
Explore the bone metabolism characteristics of premature ovarian insufficiency.
Explore the bone metabolism characteristics of premature ovarian insufficiency, indexes includes serum levels of TRACP-5b and BALP, BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck et.al.
females with premature ovarian insufficiency
Patients diagnosed by Western medicine with premature ovarian insufficiency. 18 ≤ patients' age ≤ 39 years;. Patients who voluntarily participate in this study, sign an informed consent form.
Exclusion Criteria:
Patients with congenital gonadal dysplasia or a family history similar to "early menopause".
POI patients with acquired organic lesions or ovarian surgery. Patients who have taken Western or herbal medicine artificial cycle therapy or other endocrine therapy in the past three months.
Patients with serious primary diseases and mental disorders such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system.
Patients who are breastfeeding or pregnant.
The patients with premature ovarian insufficiency
Diagnostic Test: Testing the serum levels of bone metabolic markers
Testing serum levels of TRACP-5b and BALP, BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck et.al.
tartrate resistant acid phosphatase-5b, TRACP-5b
Blood samples are collected when enrolled.
Time frame: On the 2~4th day of menstruation (amenorrhea patients are collected when enrolled)
bone specific alkaline phosphatase, BALP
Blood samples are collected when enrolled.
Time frame: On the 2~4th day of menstruation (amenorrhea patients are collected when enrolled)
bone mineral density, BMD
BMD values of lumbar spine L1-L4, left and right hip, left and right femoral neck
Time frame: On the 2~4th day of menstruation (amenorrhea patients are collected when enrolled)
Plan to share: Undecided
No publications or documents are linked to this record.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Shi Yun