An interventional study of Root canal irrigant Commiphora Myrrh 50% in Necrotic Pulp, sponsored by Cairo University. Not yet recruiting. Open to participants aged 20 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-03-13.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Among 37 studies in Dental Pulp Necrosis by Cairo University — 5 open to participants now, 5 under way, none of them phase 3. Dental Pulp Necrosis · Cairo University.
Among the 37 studies in Dental Pulp Necrosis by Cairo University, this one is the 18th largest by planned enrollment, is one of 2 that started in 2024, is one of 27 with no phase, and was the 34th registered.
157 studies on the registry are indexed under Dental Pulp Necrosis; 44 are open to participants now.
Browse Dental Pulp Necrosis studies →5 of the 37 studies in Dental Pulp Necrosis by Cairo University are open now, in 1 country. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Ages 18–40 · Healthy volunteers
Cairo University
Ages 4–7
Cairo University · Sites in Egypt
Ages 4–7 · Healthy volunteers
Cairo University
Ages 20–40 · Healthy volunteers
By country, each count listing its studies:
Of the 15 Dental Pulp Necrosis studies recruiting now, 6 (40%) set no upper age limit and 7 (47%) stop at 75 or younger; 4 take children under 18; 5 take healthy volunteers.
This study: 20 Years to 40 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
37 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 4 · Phase 2 3 · Phase 3 4 · Phase 4 2
First in 2011; this study’s year is marked. 2 started in 2024.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 42 is close to the median of 45 across 148 interventional studies indexed under Dental Pulp Necrosis.
Median enrollment 42 across the 37 interventional studies. Of the 10 that completed or were terminated, 1 (10%) have results posted.
This tab as a report to print or save as PDF → With an account.
Cairo University is the lead sponsor of 4,941 studies on the registry; 1,457 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
1 of the studies in Dental Pulp Necrosis by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07603934Cairo UniversityThe Effect of Different Intra-canal Medications on Postoperative Pain | 2027-02-15 |
Add it to your calendar (.ics) → With an account.
Among the 37 studies in Dental Pulp Necrosis by Cairo University, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
Clinically compare the post-operative pain , incidences post-operative swelling , post-operative number of analgesic tablets taken by patient and amount of bacterial load reduction after using 50% Commiphora Myrrh Chemomechanical preparation , versus 2.5% NaOCl,in asymptomatic necrotic mandibular premolar treated in single visit.
The patients will be randomly divided into 2 groups. Intervention group (50% Commiphora Myrrh solution root canal irrigant) and control group (2.5% sodium hypochlorite root canal irrigant)
Post-operative pain will be measured at 6,12,24,48 hours post-operatively The pain will be recorded using numerical rating scale
Post-operative swelling will be measured at 6,12,24,48 hours post-operatively The swelling will be receded using visual swelling rating scale
Number of analgesic tablets taken by the patient post-operatively. Up to 48 hours
Amount of bacteria load reduction The intracanal bacterial load reduction will be determined using agar culture technique by counting the colony forming units per milliliter (CFI /ml) before and after root canal preparation.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Mandibular single rooted premolars having the following criteria:
Exclusion Criteria:
Patients who could not interpret the NRS.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
50% Commiphora Myrrh
Other: Root canal irrigant Commiphora Myrrh 50%
2.5% NaOCl
Other: Root canal irrigant Commiphora Myrrh 50%
Root canal irrigant
Post-operative pain
Categorical None 0 Mild 1-3 Moderate 4-6 Sever 7-10
Time frame: Post-operative pain measured at 6,12,24,48 hours after single visit Treatment
incidence of Post-operative swelling
Categorical Of visual swelling scale of post- operative
Time frame: Up to 48 hours post-
Amount of intracanal Bacterial CFUs/ml
Intra canal bacterial load reduction will be determined using agar culture technique by counting the colony forming units per milliliter (CFUs/ml) before and after root canal preparation
Time frame: Pre-intervention, pre-instrumentation after access cavity. Post-instrumentation up to 10min
Number of analgesic Counting Tablets taken by the patient after endodontic treatment
Counting the tablet after the treatment
Time frame: Up to 48hours post-operative
No study locations are listed for this record.
Plan to share: Yes
No publications or documents are linked to this record.
Start is estimated for May 2024; primary completion for Jan 2025, 8 months later.
Of 66 non-industry interventional studies with no phase under Dental Pulp Necrosis, half reached primary completion within 16 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 35. This study's planned 8 months is below that.
Counting every sponsor, half of 67 studies reached it within 15 months; a quarter within 9 and three quarters within 31.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.