ClinicalTrials.gg
Not yet recruitingNCT06302920Updated Mar 12, 2024

Effect of Kinesiotaping on Pain,Edema and Kinesiophobia in Patients With Complex Regional Pain Syndrome

An interventional study of Kinesiotape in Complex Regional Pain Syndrome Type I, sponsored by Alanya Alaaddin Keykubat University. Not yet recruiting at 1 site in Turkey. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-03-12.

Sponsored by Alanya Alaaddin Keykubat University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jun 2024, 2 years 4 months ago, but the record still lists the study as not yet recruiting.

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Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years to 80 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 14 studies in Complex Regional Pain Syndromes with a site in Turkey — 7 open to participants now, 7 under way, none of them phase 3. Complex Regional Pain Syndromes · Turkey.

Planned enrollment
2nd of 10
60 · median 48
Started
2024
with 1 other
No phase
10 of 14
6 open now
Registered
4th of 14
by date
Lead sponsor
1 of 14
Alanya Alaaddin Keykubat University

Among the 14 studies in Complex Regional Pain Syndromes with a site in Turkey, this one is the 2nd largest by planned enrollment of the 10 interventional ones that give a count, is one of 2 that started in 2024, is one of 10 with no phase, and was the 4th registered.

Complex Regional Pain Syndromes

206 studies on the registry are indexed under Complex Regional Pain Syndromes; 55 are open to participants now.

Browse Complex Regional Pain Syndromes studies →

Open to participants now

7 of the 14 studies in Complex Regional Pain Syndromes with a site in Turkey are open now. Recruiting first, the newest first:

1 more — sign in →

All 7 open studies →

A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →

Who these studies take

Of the 39 Complex Regional Pain Syndromes studies recruiting now, 17 (44%) set no upper age limit and 16 (41%) stop at 75 or younger; 3 take children under 18; 5 take healthy volunteers.

This study: 18 Years to 80 Years · all sexes · no healthy volunteers.

The full table on the hub →

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02

Study summary

Patients will be divided into 2 groups according to the random numbers table, and both groups will receive a conventional physical therapy and rehabilitation program and nutritional support. Afterwards, edema-reducing kinesiotaping will be applied to one group. The applied kinesio tape will remain on the patient for 5 days and will be taped again after 2 days without tape. In this way, taping will be done 3 times in total, once a week for 3 weeks. During this period, patients will continue their routine physical therapy program and measurements will be taken by the same researcher in the 1st week of treatment and 3 weeks later.

Read the detailed description

Patients will be divided into 2 groups according to the random numbers table, and both groups will receive a conventional physical therapy and rehabilitation program and nutritional support. Afterwards, edema-reducing kinesiotaping will be applied to one group. The applied kinesio tape will remain on the patient for 5 days and will be taped again after 2 days without tape. In this way, taping will be done 3 times in total, once a week for 3 weeks. During this period, patients will continue their routine physical therapy program and measurements will be taken by the same researcher in the 1st week of treatment and 3 weeks later.

Kinesiology tapes have a wavy structure in line with the structure and physiological functions of the skin and have adhesive properties. The adhesive is a heat-activated acrylic. After approximately 20 minutes, the adhesive is fully activated. The tapes are porous, permeable to air and liquid, allow perspiration and dry quickly.Kinesiology tapes have a wavy structure in line with the structure and physiological functions of the skin and have adhesive properties. The adhesive is a heat-activated acrylic. After approximately 20 minutes, the adhesive is fully activated. The tapes are porous, permeable to air and liquid, allow perspiration and dry quickly. The method of application varies depending on the cutting method, application direction and region of the tape. If the anatomy of muscles, joints, ligaments and circulatory system is mastered and the correct techniques appropriate to the situation are used, the chance of success of the technique increases. Lymphatic correction technique is used to reorganize damaged lymphatic circulation. The main goals are to create a dead space in the tissue that allows circulation and to reduce the pressure on the lymph vessels at the tissue level. It directs lymph fluid to larger lymphatic vessels and lymph nodes. This effect can be explained by the elastic qualities and lifting effect of the tape. While lifting the surface skin reduces pressure and ensures lymphatic circulation, the tape provides a massage effect during active movement. Thanks to the tape, maximum contraction and relaxation of the muscles is ensured and the effectiveness of the deeper lymphatic flow is increased.

Kinesiophobia (also known as fear of movement); It is defined as an excessive and irrational fear of physical movement to avoid being harmed or injured again. It can also be expressed as an excessive, irrational fear of physical movement and activity resulting from a feeling of vulnerability due to pain. Its prevalence in chronic pain varies between 50-70%. While the existing threatening characteristics of the pain experience may vary depending on the situation and the person, avoidance behavior, which is protective in the short term, paradoxically worsens the problem in the long term. It is stated that kinesiophobia is an important factor in the transition of pain from acute to chronic stages.

03

Conditions studied

  • Complex Regional Pain Syndrome Type I

Keywords

  • complex regional pain syndrome
  • kinesiotaping
  • Kinesiophobia
04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Clinical diagnosis of reflex sympathetic dystrophy Ability to be included in a physical therapy program

Exclusion criteria

Exclusion Criteria:

Hemiplegia Polyacrylamide allergy Open wound in the area to be applied

Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
60 participants (estimated)

Study arms

  • Active comparator
    Kinesiotaping group

    Patients will be divided into 2 groups according to the random numbers table, and both groups will receive a conventional physical therapy and rehabilitation program and nutritional support. Afterwards, edema-reducing kinesiotaping will be applied to one group.

    Device: Kinesiotape

  • No intervention
    Control group

    Patients will be divided into 2 groups according to the random numbers table, and both groups will receive a conventional physical therapy and rehabilitation program and nutritional support.

Interventions

  • DeviceKinesiotape

    Lymphatic correction technique

06

What researchers measure

Primary outcomes

  1. Resting pain

    The resting pain level of the patients will be measured with the Visual Analogue Scale (VAS).A score between 0 and 10 will be determined by the patient, with 0 being no pain and 10 being the most severe pain level.

    Time frame: Beginning, week 3 and week 6

  2. Edema

    The patients will be physically examined and their wrist circumference and metacarpal circumference will be measured in centimeters.

    Time frame: Beginning, week 3 and week 6

  3. Kinesiophobia

    Kinesiophobia will be assessed using the Tampa Scale for Kinesiophobia. A score above 37 in the test is defined as an indicator of a high level of kinesiophobia.

    Time frame: Beginning, week 3 and week 6

07

Study locations

1 site
08

References and documents

Publications

  • Fischer SGL, Zuurmond WWA, Birklein F, Loer SA, Perez RSGM. Anti-inflammatory treatment of Complex Regional Pain Syndrome. Pain. 2010 Nov;151(2):251-256. doi: 10.1016/j.pain.2010.07.020. Epub 2010 Aug 7. No abstract available. PubMed 20692766 ↗
  • Çeliker R, Güven Z, Aydoǧ T, et al. Kinezyolojik bantlama tekniǧi ve uygulama alanlari. Turkiye Fiz Tip ve Rehabil Derg. 2011;57(4):225-235.
  • Roelofs J, van Breukelen G, Sluiter J, Frings-Dresen MHW, Goossens M, Thibault P, Boersma K, Vlaeyen JWS. Norming of the Tampa Scale for Kinesiophobia across pain diagnoses and various countries. Pain. 2011 May;152(5):1090-1095. doi: 10.1016/j.pain.2011.01.028. PubMed 21444153 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for May 2024; primary completion for Jun 2024, 1 month later.

Of 64 non-industry interventional studies with no phase under Complex Regional Pain Syndromes, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 14 and three quarters within 60. This study's planned 1 month is below that.

Counting every sponsor, half of 65 studies reached it within 24 months; a quarter within 14 and three quarters within 60.

How these figures are worked out, and which studies are left out of them.

Registered
Feb 7, 2024
First posted
Mar 12, 2024
StartEst.
May 20, 2024
Primary completionEst.
Jun 20, 2024
CompletionEst.
Dec 20, 2024
Last update
Mar 12, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 12, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06302920
Lead sponsor
Alanya Alaaddin Keykubat University
Responsible party
Deniz Bulut (assistant professor, Alanya Alaaddin Keykubat University) — Principal investigator
First posted
Mar 12, 2024
Start date
May 20, 2024 (estimated)
Primary completion
Jun 20, 2024 (estimated)
Completion
Dec 20, 2024 (estimated)
Last update
Mar 12, 2024

Study contacts

Deniz Bulut, A.professor
Contact
denizhava1988@gmail.com
+90 05059445604
Deniz Bulut, A.professor
principal investigator · Alanya Alaaddin Keykubat University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.

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