An interventional study of Whirlpool Bath and Contrast Bath in Distal Radius Fracture, Complex Regional Pain Syndrome Type I and Complex Regional Pain Syndrome, sponsored by Afyonkarahisar Health Sciences University. Recruiting at 1 site in Turkey. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2025-01-30.
Sponsored by Afyonkarahisar Health Sciences University · Not applicable, Interventional, and Supportive care
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Among 27 studies in Wrist Fractures with a site in Turkey — 6 open to participants now, 6 under way, none of them phase 3. Wrist Fractures · Turkey.
Among the 27 studies in Wrist Fractures with a site in Turkey, this one is the 12th largest by planned enrollment of the 19 interventional ones that give a count, is one of 2 that started in 2025, is one of 18 with no phase, and was the 18th registered.
330 studies on the registry are indexed under Wrist Fractures; 72 are open to participants now.
Browse Wrist Fractures studies →6 of the 27 studies in Wrist Fractures with a site in Turkey are open now. Recruiting first, the newest first:
Dilek ün oguzhanasilturk · Sites in Turkey
Ages 18–75
Pamukkale University · Sites in Turkey
Ages 18–65
Hacettepe University · Sites in Turkey
Ages 18+
Pamukkale University · Sites in Turkey
Ages 18–65
Istanbul University · Sites in Turkey
Ages 18–65
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 43 Wrist Fractures studies recruiting now, 20 (47%) set no upper age limit and 15 (35%) stop at 75 or younger; 7 take children under 18; 6 take healthy volunteers.
This study: 18 Years to 70 Years · all sexes · no healthy volunteers.
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27 studies; the count open now beside each. This study's row is marked.
First in 2014; this study’s year is marked. 2 started in 2025.
This study's planned enrollment of 40 is below the median of 63 across 265 interventional studies indexed under Wrist Fractures.
Median enrollment 44 across the 19 interventional studies, 80 across the 8 observational. Of the 20 that completed or were terminated, 0 (0%) have results posted.
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None of the 27 has an industry lead sponsor. The 10 most frequent:
Afyonkarahisar Health Sciences University is the lead sponsor of 115 studies on the registry; 32 are open to participants now.
Afyonkarahisar Health Sciences University has 1 study filed under Wrist Fractures — fewer than ten, so there is no comparison to draw.
3 of the studies in Wrist Fractures with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07522060Hacettepe UniversityEarly Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System | 2026-12-30 |
| NCT07291505Pamukkale UniversityThe Investigation of Kinesiophobia in Conservative Distal Radius Fractures | 2026-12-30 |
| NCT07807852Dilek ün oguzhanasilturkESWT for CRPS-I After Distal Radius Fracture | 2027-06-26 |
Add all 3 to your calendar (.ics) → With an account.
Among the 27 studies in Wrist Fractures with a site in Turkey, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
The aim of our study is to investigate the effects of whirlpool bath and contrast bath treatments on pain, disability, functionality and grip strength in patients with complex regional pain syndrome after distal radius fracture.
Distal radius fractures are the most common fracture type among all body bone fractures. Fractures generally occur in elderly patients caused by low-energy trauma due to decreased bone quality. In young patients, they mostly occur due to traumas such as traffic accidents, falls from heights and sports injuries.
One of the important complications seen after distal radius fractures is complex regional pain syndrome (CRPS). Complex regional pain syndrome represents a complication following distal radius fractures that is still not fully understood etiologically.
Studies have shown that complex regional pain syndrome is commonly diagnosed among patients recovering from a fracture of the distal radius with a reported incidence as high as 37%. It is characterized by excessive pain (allodynia and/or hyperalgesia), edema, local blood flow changes and abnormality of the sudomotor nerve.
There are hardly any studies with a sufficient evidence level to make recommendations for treatments for CRPS-1; therefore, treatment is based on symptom management. Prevention of CRPS-1, after a distal radius fracture is important as this syndrome might lead to chronic pain and serious disabilities. In several studies, it was shown that CRPS-1 can be cured with exercise and graded activities. The main goals of physiotherapy are to reduce pain, regain range of motion, and increase muscle strength and function.
Whirlpool bath and contrast bath treatments are physical therapy methods that has been used safely in complex regional pain syndrome treatment for many years.
Whirlpool baths are local baths where the extremities are immersed in rapidly circulating water. The swirling water produced by the whirlpool bath creates a massaging effect on the body, which can help relieve muscle tension and alleviate pain. The combination of warm water and hydrostatic pressure can also enhance blood circulation and improve joint mobility.
Contrast baths constitute a thermal modality whereby the hand is alternately immersed in hot and cold water for a specified temperature, time, and duration to therapeutically decrease edema, stiffness, pain and increase functionality in cases of complex regional pain syndrome after fractures.
Our primary aim is to investigate the effects of whirlpool bath and contrast bath treatments on pain, disability, functionality and grip strength in patients who were followed conservatively with complex regional pain syndrome (CRPS-1) after distal radius fracture.
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Exclusion Criteria:
An exercise program consisting of hand-wrist range of motion exercises, stretching, strengthening exercises, whirlpool bath therapy and transcutaneous electrical nerve stimulation (TENS) is planned for 4 weeks.
Device: Whirlpool Bath
An exercise program consisting of hand-wrist range of motion exercises, stretching, strengthening exercises, contrasth bath therapy and transcutaneous electrical nerve stimulation (TENS) is planned for 4 weeks.
Device: Contrast Bath
This group of participants will receive an exercise program consisting of 40 minutes hand-wrist range of motion exercises (passive, active assistive), stretching, strengthening exercises, whirlpool bath (32-38 °C) 20 minutes in total, transcutaneous electrical nerve stimulation (TENS) 20 minutes in total for 4 weeks. 5 sessions per week for 20 sessions in the Physical Therapy department.
This group of participants will recieve an exercise program consisting of 40 minutes hand-wrist range of motion exercises (passive, active assistive), stretching, strengthening exercises, contrast bath therapy which consist of 4 minutes hot water (38°C) followed by 1 minute cold water (10°C) periods for 20 minutes in total, transcutaneous electrical nerve stimulation (TENS) 20 minutes in total for 4 weeks. 5 sessions per week for 20 sessions in the Physical Therapy department.
Range of Motion Measurement
Supination and pronation of the forearm, flexion, extension, ulnar and radial deviation active/passive range of motion of the wrist will be evaluated with a universal goniometer. Patients will be examined three times in total: before treatment, after treatment (4th week) and at 12th week.
Time frame: up to 12th week
Hand grip strength measurement with Jamar Dynamometer
Jamar Dynamometer measures isometric grip force and strength. Measurements will be made by sitting with the shoulder adducted and neutrally rotated, adjacent to the body, elbow flexed at 90 degrees, wrist dorsiflexed at 0-30 degrees and ulnar deviation at 0-15 degrees with the thumb pointing up. Measurements will be repeated three times, 5 seconds apart, on the hand on the affected side, and the average of the three measurements will be recorded in kilograms. Patients will be examined three times in total: before treatment, after treatment (4th week) and at 12th week.
Time frame: up to 12th week
Jebsen Taylor Hand Function Test
This test consists of tasks involving types of grasping commonly used in daily life and evaluates the speed of individuals in these tasks.The JTHFT has seven subsets which are writing, simulated page-turning, lifting small objects, simulated feeding, stacking, and lifting large, lightweight, and heavy objects. The test's scoring is recorded as the time it takes for the person to complete the tasks. Patients will be examined three times in total: before treatment, after treatment (4th week) and at 12th week.
Time frame: up to 12th week
The Disabilities of the Arm, Shoulder and Hand Score (Q-DASH)
Q-DASH includes 11 items extracted from the DASH questionnaire that measure physical functions and symptoms in patients with upper extremity problems. Each answer is scored from 1 to 5 on a Likert scale from good to bad; 1: no difficulty, 2: mild difficulty, 3: moderate difficulty, 4: extreme difficulty, 5: no ability to do. Each section of the Quick-DASH questionnaire is scored between 0-100 (0= no disability, 100= maximum disability). Patients will be examined three times in total: before treatment, after treatment (4th week) and at 12th week.
Time frame: up to 12th week
Patient-rated Wrist Evaluation Form
Patient-rated Wrist Evaluation Form consists of 15 questions that measure the severity of wrist pain and the level of disability in daily life activities. It has two subsections. The pain subsection consists of four questions on pain intensity and frequency, while the function subsection consists of six questions on specific activities and four questions on daily activities. Questions are rated on a 10-point scale (where 0 is no pain and 10 is worst pain). Patients will be examined three times in total: before treatment, after treatment (4th week) and at 12th week.
Time frame: up to 12th week
Short Form 36 (SF-36)
SF-36 is a frequently used questionnaire that evaluates the functional health and well-being of patients with 36 different items. These are; physical function, physical role limitation, emotional role limitation, energy/fatigue, mental health, social function, body pain and general health perception. In the evaluation made with this scale, the last 4 weeks are taken into account and the scoring is Likert type except for some items. A total score is calculated separately for each sub-item. The scores are between "0" and "100". While the value of "100" indicates good health status, the value of "0" indicates poor health status. Patients will be examined three times in total: before treatment, after treatment (4th week) and at 12th week.
Time frame: up to 12th week
Visual Analog Scale (VAS)
This method, which is aimed at determining the intensity of pain, aims to have the patient describe their pain with numbers. It is a 10 cm long line that starts with no pain (0) and ends with unbearable pain (10). Patients will be examined three times in total: before treatment, after treatment (4th week) and at 12th week.
Time frame: Up to 12th week
Plan to share: No
Start is estimated for Jan 2025; primary completion for Mar 2025, 1 month later.
Of 126 non-industry interventional studies with no phase under Wrist Fractures, half reached primary completion within 25 months of starting (the median), counting those still running; a quarter within 16 and three quarters within 50. This study's planned 1 month is below that.
Counting every sponsor, half of 127 studies reached it within 25 months; a quarter within 16 and three quarters within 50.
How these figures are worked out, and which studies are left out of them.
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