CClinicalTrials.gg
Not yet recruitingNCT06235359Updated Jan 31, 2024

Is Intercostal Tube Enough in Management of Empyema

An interventional study of intercostal tube in Empyema, sponsored by Assiut University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2024-01-31.

Sponsored by Assiut University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Not applicable
Sex
All
01

Study summary

Is intercostal tube enough in management of empyema ?

Read the detailed description

Empyema refers to presence of pus in the pleural space -Causes Primary: bacterial Pneumonia (staph aureus, strept pneumonia , H.influenza) , TB

Secondry :

PostTraumati postoperative :open heart , esophageal, mediastinum , lung rupture of lung absess

-pathophysiology and stages During an inflammatory process such as pneumonia, there is an increase in fluid production in the pleural cavity known as the exudate stage. As the disease progresses microorganisms, usually bacteria, can colonize the fluid and generated an empyema. This fluid is characterized by elevated lactate dehydrogenase, proteins, neutrophils, and dead cells. Macroscopically is a thick opaque fluid found in the fibrinopurulent stage. After the resolution of the infection and as a consequence of the inflammation, there is a process of fibrosis that can lead to restriction of the lung parenchyma which is stage of chronic organization

02

Conditions studied

  • Empyema

Browse trials for

03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • patients admitted to Assuit university Hospital and diagnosed with empyema

Exclusion criteria

Exclusion Criteria:

  • Patient diagnosed with Post-operative empyema
  • Patient diagnosed with post traumatic empyema
  • Patient diagnosed with Bronchopleural fistula
  • Patient diagnosed with TB
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
100 participants (estimated)

Study arms

  • Other
    intercostal tube

    A chest tube is a hollow, flexible tube placed into the chest. It acts as a drain. Chest tubes drain blood, fluid, or air from around your lungs, heart, or esophagus. The tube around your lung is placed between your ribs and into the space between the inner lining and the outer lining of your chest cavity. This is called the pleural space. It allows your lungs to fully expand.

    Device: intercostal tube

Interventions

  • Deviceintercostal tube

    A chest tube is a hollow, flexible tube placed into the chest. It acts as a drain. Chest tubes drain blood, fluid, or air from around your lungs, heart, or esophagus. The tube around your lung is placed between your ribs and into the space between the inner lining and the outer lining of your chest cavity. This is called the pleural space. It allows your lungs to fully expand.

05

What researchers measure

Primary outcomes

  1. To find best way to drain the pus in the pleural space

    To find best way to drain the pus in the pleural space

    Time frame: baseline

06

Study locations

No study locations are listed for this record.

07

References and documents

Publications

  • Ali I, Unruh H. Management of empyema thoracis. Ann Thorac Surg. 1990 Sep;50(3):355-9. doi: 10.1016/0003-4975(90)90474-k. PubMed 2400254 ↗
08

Registry details

Key details

Study ID
NCT06235359
Lead sponsor
Assiut University
Responsible party
Islam Abdelfatah mahmoud (physician, Assiut University) — Principal investigator
First posted
Jan 31, 2024
Start date
Mar 2024 (estimated)
Primary completion
Nov 2026 (estimated)
Completion
Dec 2026 (estimated)
Last update
Jan 31, 2024

Study contacts

Islam abdelfatah, resident
Contact
Islam.abdelfatah.097@gmail.com
01024984239
Mahmoud khairy, professor
Contact
Mahkhairy02@yahoo.com
01098935293

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion