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CompletedNCT06213142CBToolkitUpdated Jan 19, 2024

Developing the Unified Protocol-Single Session Experience Platform for Adolescent Mental Health

An interventional study of CBToolkit in Depression, Depression, Anxiety and Depression in Adolescence, sponsored by 3-C Institute for Social Development. Completed at 1 site in United States. Open to participants aged 13 Years to 17 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-01-19.

Sponsored by 3-C Institute for Social Development · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
57
Allocation
Not applicable
Ages
13 Years to 17 Years
Sex
All
01

Study summary

This SBIR Phase I proposal will develop and test the acceptability and feasibility of a new suite of digital Single-Session Interventions, specifically applying Unified Protocol core principles for emotional disorders, to produce a highly accessible, engaging, and scalable product to help address the clinical needs of youth.

Read the detailed description

This project proposes develop a suite of Single Session Intervention (SSI) modules using the Unified Protocol (UP) core principles. For Phase I, the team will develop two SSI modules from UP: Awareness of Physical Sensations and Emotional Experiences, and Being Flexible in Your Problem Solving. For the acceptability test (Specific Aim 2), investigators will recruit 60 youth who are screened as eligible based on the internalizing subscale of the Pediatric Symptom Checklist. Caregivers/parents of youth will be recruited using targeted social media advertisements, where they can view a brief study description and complete the eligibility screener. If interested, caregivers can provide contact information for the study team to conduct consent and assent processes. Following consent and enrollment, participants will receive private login information to access the prototype and study materials. First, participants will complete pre-surveys that collect demographic information and responses to the Revised Children's Anxiety and Depression Scale (RCADS). Next, participants will take a brief survey to assess knowledge of intervention concepts presented in the first module: Mindful Awareness. Then, they will engage with the module and provide feedback on the quality of its components. Then, they will complete the knowledge assessment again. Participants will complete the same process for the second module: Flexible Problem Solving (pre knowledge check, review, rate the quality, and post knowledge check). Participants will complete a product evaluation to rate their overall experience with the prototype (quality, usability, innovation, feasibility, and value) and the degree they advocate for full product development. Finally, participants will take the RCADS at the end of the review period. There will also be an opportunity for participants to participate in a brief feedback call to provide additional feedback.

02

Conditions studied

  • Depression
  • Depression, Anxiety
  • Depression in Adolescence
  • Anxiety
03

Who can participate

Ages eligible
13 Years to 17 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • be ages 13 to 17 years old
  • be willing and available to take part in the study requirements
  • be fluent in English
  • have access to the internet with a mobile device or personal computer
  • have parent permission
  • screen as eligible according to the internalizing subscale from the Pediatric Symptom Checklist

Exclusion criteria

Exclusion Criteria:

04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
57 participants (actual)

Study arms

  • Experimental
    CBToolkit

    CBToolkit includes two SSI modules: (1) Mindful Awareness, with the goal of increasing awareness and tolerance of physical sensations and emotional experiences using mindfulness practices and tips and (2) Flexible Problem Solving, with the goal of promoting cognitive flexibility, applying problem-solving strategies in difficult scenarios, and learning to modify behavioral action tendencies.

    Other: CBToolkit

Interventions

  • OtherCBToolkit

    CB Toolkit Mindful Awareness module to increase awareness and tolerance of physical sensations and emotional experiences using mindfulness practices. The module involves videos with motion graphics, video demos, voiceover, music, and sound effects intermixed throughout with a variety of interactive exercises tailored to specific core components. The module aims to establish understanding of the intervention concept (psychoeducation), increase self-efficacy in mindfulness skills via active practice and personalized feedback, and facilitate self-reflection and understanding of strengths and improvement areas related to mindfulness. CBToolkit Flexible Problem Solving module to promote cognitive flexibility, applying problem-solving strategies in difficult scenarios, and learning to modify behavioral action tendencies. Videos and activities will be tailored to provide examples of effective problem-solving techniques and provide personalized reinforcing and/or scaffolded feedback.

05

What researchers measure

Primary outcomes

  1. Program Feedback Scale for Adolescents

    Adolescents will complete this 12-item measure, rating the extent to which they agree with statements about the usability, acceptability, and feasibility of the CBToolkit modules. The measure includes 9 Likert items and 3 open-ended items. Responses to the Likert items range from 1 (Really Disagree) to 5 (Really Agree). Total scores are based on the Likert items are range from 0 to 45. Higher scores reflect more positive opinions.

    Time frame: 2 week followup post module review

  2. Module Knowledge

    Adolescents will complete this 9-item measure to determine what they know about key concepts taught in the CBToolkit module prior to and following review of the modules. The measure includes 9 multiple choice items with a 1 correct response per item. Total scores are based on the number of items with correct responses and range from 0 to 9. Higher scores reflect more correct responses.

    Time frame: Average of 2 weeks apart, as pre- and post-tests

  3. Revised Children's Anxiety and Depression Scale- Shortened

    Adolescents will complete the shortened 11-item version of this measure to assess levels of anxiety and depression prior to and following review of the modules. The measure includes 11 Likert items. Responses to the Likert items range from 0- Never to 3- Always. Total scores are based on the Likert items are range from 0 to 33. Higher scores reflect more severe symptoms.

    Time frame: Average of 2 weeks apart, as pre- and post-tests

Secondary outcomes

  1. Usage Metrics from the CBToolkit system for adolescents

    The CBToolkit software will tracks progress through the modules, and the length of time spent on each sections of the module. These metrics are measured in seconds. A longer time generally indicates more time spent with the content.

    Time frame: The period in which adolescents interact with the system, approximately 2 weeks

  2. Feedback interviews with adolescents

    Adolescents will participate in individual interviews. They will be asked about their experience with the CBToolkit, strengths and weaknesses of CBToolkit, and challenges to using CBToolkit.. Comments will be combined and grouped based on themes in a qualitative summary.

    Time frame: 15-minutes, completed after the test of the CBToolkit system

06

Study locations

1 site
  • 3C Institute
    Durham, North Carolina 27713, United States
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT06213142
Lead sponsor
3-C Institute for Social Development
Collaborators
University of Miami, Stony Brook University
Responsible party
Sponsor
First posted
Jan 19, 2024
Start date
Jun 1, 2023
Primary completion
Aug 31, 2023
Completion
Aug 31, 2023
Last update
Jan 19, 2024

Study contacts

Melissa DeRosier, PhD
principal investigator · 3C Institute
Jill Ehrenreich-May, PhD
principal investigator · University of Miami
Jessica Schleider, PhD
principal investigator · StoneyBrook University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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