CClinicalTrials.gg
RecruitingNCT06197958Updated Jan 9, 2024

Comparison of Concentric-eccentric Exercises in Patellofemoral Pain Syndrome

An interventional study of eccentric exercises and concentric exercises in Patello Femoral Syndrome, Patellofemoral Pain and Knee Pain Chronic, sponsored by Riphah International University. Recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 36 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-01-09.

Sponsored by Riphah International University · Not applicable, Interventional, and Other

From the registry’s dates

  • Primary completion was expected by Feb 2024, 2 years 7 months ago, but the record still lists the study as recruiting.
  • Started Oct 2023; still recruiting 2 years 11 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
24
Allocation
Randomized
Ages
18 Years to 36 Years
Sex
All
01

Study summary

Patellofemoral pain syndrome is due to dysfunctional dynamic knee valgus resulting from decrease in strength of hip abductors or abnormal rear-foot eversion with pes pronatus valgus. It is also associated with vastus medialis/vastus lateralis disbalance, hamstring tightness or iliotibial tract tightness.

Read the detailed description

Patellofemoral pain syndrome is due to dysfunctional dynamic knee valgus resulting from decrease in strength of hip abductors or abnormal rear-foot eversion with pes pronatus valgus. It is also associated with vastus medialis/vastus lateralis disbalance, hamstring tightness or iliotibial tract tightness. The pain is felt around or behind the patella. The causes are multifactorial. A decline in ability to perform physical activity is seen. The aim of this study will be to compare the effects of concentric and eccentric exercises on pain, strength and ROM in patellofemoral pain syndrome.A randomized clinical trial will be performed at Barki Advance Physiotherapy Center Multan through convenience sampling technique on 24 patients which will be allocated through random sampling through sealed opaque enveloped into group A and group B. Group A will receive eccentric exercises like walking down stairs, lowering a weight during shoulder press, the downward motion of squatting, the downward motion of a push-up, lowering the body during a crunch, lowering the body during a pull-up 3 sets with 10 RM (repetition maximum) for six week training. The group B will receive concentric exercises like walking upstairs, pushing up in a bench press, the beginning portion of a deadlift when you lift the barbell off the ground, sitting up in a sit up, pushing up from a lowered push-up and standing up in a back squat 3 sets with 10 RM. Screening tools include patellar grind test with positive Clark's sign and VAS (visual analogue scale) for pain rating. Outcomes will be measured through knee resisted test and MMT grading for knee extensor/flexor strength and goniometer for ROM. Data will be analyzed using SPSS software version 25. After assessing normality, it will be decided either parametric or non parametric test will be used within a group or between two groups. Effectiveness of concentric and eccentric exercises will be analyzed by comparison in individuals with patellofemoral pain syndrome.

02

Conditions studied

  • Patello Femoral Syndrome
  • Patellofemoral Pain
  • Knee Pain Chronic

Keywords

  • concentric excercise
  • eccentric excercise
  • Iliotibial Band
03

In context

Patellofemoral Pain Syndrome

295 studies on the registry are indexed under Patellofemoral Pain Syndrome; 75 are open to participants now.

This study's planned enrollment of 24 is below the median of 45 across 242 interventional studies indexed under Patellofemoral Pain Syndrome.

Browse Patellofemoral Pain Syndrome studies →

Lead sponsor

Riphah International University is the lead sponsor of 2,133 studies on the registry; 633 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 36 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Players between the age 18 to 36 years.
  • Both male and female gender.
  • Patients who have Patellar grind test positive.
  • The presence of retropatellar or peripatellar pain.
  • Reproduction of retropatellar or peripatellar pain with squatting, stair climbing, prolonged sitting, or other functional activities loading the PFJ in a flexed position.

Exclusion criteria

Exclusion Criteria:

  • Individuals with a history of recent trauma or surgery of lower limb (16), administration of steroid injection in the past 6 months.
  • Recent administration of platelet-rich plasma containing growth factors, diagnosis of rheumatoid arthritis, myositis ossificans, diagnosis of other muscular disorder.
  • Patients who had taken physical therapy of any sort in the past six months will be excluded from the study.
  • Furthermore, individuals with any history of occupation-related pain will be ruled out
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
24 participants (estimated)

Study arms

  • Experimental
    eccentric exercises

    Group A: Group A will receive 3 sets of eccentric exercises with 10 RM (repetition maximum) in six sessions.

    Other: eccentric exercises

  • Experimental
    concentric exercises

    Group B: Group B will receive 3 sets of concentric exercises with 10 RM in six sessions

    Other: concentric exercises

Interventions

  • Othereccentric exercises

    eccentric exercises like walking down stairs, lowering a weight during shoulder press, the downward motion of squatting, the downward motion of a push-up, lowering the body during a crunch, lowering the body during a pull-up 3 sets with 10 RM (repetition maximum) for six week training.

  • Otherconcentric exercises

    concentric exercises like walking upstairs, pushing up in a bench press, the beginning portion of a deadlift when you lift the barbell off the ground, sitting up in a sit up, pushing up from a lowered push-up and standing up in a back squat 3 sets with 10 RM.

06

What researchers measure

Primary outcomes

  1. patellofemoral pain

    pain is measured by VAS (Visual Analogue Scale)

    Time frame: pre and 6 weeks post interventional

  2. range of motion

    ROM is measured by goniometer

    Time frame: pre and 6 weeks post interventional

  3. knee extensor/flexor strength

    knee extensor/flexor strength is measured by knee resisted test and MMT grading

    Time frame: pre and 6 weeks post interventional

07

Study locations

1 of 1 sites recruiting
  • barki advance physiotherapy center Multan
    Multān, Punjab 60000, Pakistan
    Recruiting
08

References and documents

Publications

  • Crossley KM, Stefanik JJ, Selfe J, Collins NJ, Davis IS, Powers CM, McConnell J, Vicenzino B, Bazett-Jones DM, Esculier JF, Morrissey D, Callaghan MJ. 2016 Patellofemoral pain consensus statement from the 4th International Patellofemoral Pain Research Retreat, Manchester. Part 1: Terminology, definitions, clinical examination, natural history, patellofemoral osteoarthritis and patient-reported outcome measures. Br J Sports Med. 2016 Jul;50(14):839-43. doi: 10.1136/bjsports-2016-096384. Epub 2016 Jun 24. No abstract available. PubMed 27343241 ↗
  • Glaviano NR, Kew M, Hart JM, Saliba S. DEMOGRAPHIC AND EPIDEMIOLOGICAL TRENDS IN PATELLOFEMORAL PAIN. Int J Sports Phys Ther. 2015 Jun;10(3):281-90. PubMed 26075143 ↗
  • Petersen W, Ellermann A, Gosele-Koppenburg A, Best R, Rembitzki IV, Bruggemann GP, Liebau C. Patellofemoral pain syndrome. Knee Surg Sports Traumatol Arthrosc. 2014 Oct;22(10):2264-74. doi: 10.1007/s00167-013-2759-6. Epub 2013 Nov 13. PubMed 24221245 ↗
  • Smith BE, Selfe J, Thacker D, Hendrick P, Bateman M, Moffatt F, Rathleff MS, Smith TO, Logan P. Incidence and prevalence of patellofemoral pain: A systematic review and meta-analysis. PLoS One. 2018 Jan 11;13(1):e0190892. doi: 10.1371/journal.pone.0190892. eCollection 2018. PubMed 29324820 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 9, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06197958
Lead sponsor
Riphah International University
Responsible party
Sponsor
First posted
Jan 9, 2024
Start date
Oct 20, 2023
Primary completion
Feb 20, 2024 (estimated)
Completion
Feb 20, 2024 (estimated)
Last update
Jan 9, 2024

Study contacts

Amna Shahid, MS-DPT
Contact
amna.shahid@riphah.edu.pk
+92 334 4512823
moiz kamal, DPT
principal investigator · study principal investigator

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion