An observational study in Tree Nut Allergy and Food Allergy, sponsored by Hamilton Health Sciences Corporation. Recruiting at 1 site in Canada. Open to participants aged 3 Months to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-06-03.
Sponsored by Hamilton Health Sciences Corporation · Observational
Thresholds In food allergy evaluaTion And predictioN, a prospective, observational registry. The aim is to quantify food allergy thresholds in Canada and their clinical predictors.
33 studies on the registry are indexed under Nut Hypersensitivity; 9 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 240 across 11 observational studies indexed under Nut Hypersensitivity.
Browse Nut Hypersensitivity studies →Hamilton Health Sciences Corporation is the lead sponsor of 242 studies on the registry; 38 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All consecutive patients suspected or confirmed to be food allergic
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Clinically significant
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients with suspected or confirmed food allergy
Diagnostic Test: Oral food challenge
Patients will undergo oral food challenge with increasing amounts of food allergen
Eliciting dose thresholds to food challenge
Threshold are measured by controlled food challenge to incremental doses of allergen (g) and are adjudicated according to CoFAR v3.0 criteria
Time frame: 1 year
Food Allergy Quality of Life Questionnaire Child Form
The number of items found in the child form questionnaire includes 30 items. Food allergy quality of life questionnaire is answered on a 7-point scale (0 to 6) with higher scores representing worse impairment.
Time frame: 1 year
Food Allergy Quality of Life Questionnaire Teen Form
The number of items found in the Teen Form questionnaire includes 26 items. Food allergy quality of life questionnaire is answered on a 7-point scale (0 to 6) with higher scores representing worse impairment.
Time frame: 1 year
Food Allergy Quality of Life Questionnaire Adult Form
The number of items found in the Adult Form questionnaire includes 35 items. Food allergy quality of life questionnaire is answered on a 7-point scale (0 to 6) with higher scores representing worse impairment.
Time frame: 1 year
Food Allergy Quality of Life Questionnaire Parent Form
The number of items found in the Parent Form questionnaire includes 38 items. Food allergy quality of life questionnaire consists of 3 to 4 domains, each question is answered on a 7-point scale (0 to 6) with higher scores representing worse impairment.
Time frame: 1 year
Skin Prick Testing
Measured by mean wheal size (mm)
Time frame: 1 year
Specific IgE
Measured by ImmunoCap (kU/L)
Time frame: 1 year
Basophil Activation Test
Measured by flow cytometry (cell frequency basophils and median fluorescence intensity)
Time frame: 1 year
Plan to share: No — Will consider on a case by case basis.
No publications or documents are linked to this record.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Hamilton Health Sciences Corporation →