Food Hypersensitivity clinical trials
The registry lists 376 studies for Food Hypersensitivity across more than 10 countries. 90 are recruiting or about to start. 212 of them are mainly about Food Hypersensitivity (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 5 narrower conditions too, such as Peanut Hypersensitivity: 598 studies, 122 open.
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Status
Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (18) · Medical University of Warsaw (14) · Johns Hopkins University (11) · University of North Carolina, Chapel Hill (8) · Federico II University (8) · Stanford University (8) · DBV Technologies (7) · Central Hospital, Nancy, France (7)
What is being tested here
Drugs under test in Food Hypersensitivity studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Omalizumab | 4 | 0 | 12 |
| Remibrutinib | 1 | 1 | 2 |
| LP-003 | 1 | 0 | 1 |
| Peanut | 0 | 0 | 6 |
| cow's milk | 0 | 0 | 5 |
| Palforzia | 0 | 2 | 4 |
| EpiCeram | 0 | 1 | 2 |
| Dupilumab | 0 | 0 | 2 |
| Milk Proteins | 0 | 0 | 2 |
| Ligelizumab | 0 | 2 | 2 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers) · Phase 3 · DBV Technologies
- Apr 2027Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study · Phase 3 · Pablo Rodríguez del Rio
- May 2027The PEBBLES Study - Testing a Strategy for Preventing Eczema and Food Allergy in High Risk Infants · Phase 3 · University of Melbourne
- Nov 2026TRADE Trial - Tree Nut Immunotherapy Route Development and Evaluation · Hamilton Health Sciences Corporation
- Nov 2026Evaluation of The Food Allergy Mastery Program · Children's National Research Institute
- Nov 2026Pectin Intervention Study and Long-term Follow-up in Lipid Transfer Proteins Allergic Patients · Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
- Dec 2026Food Oral Immunotherapy for Peanut Allergy · Massachusetts General Hospital
- Dec 2026Understanding the Immune System's Role in Tree Nut and Peanut Allergies: Key Biomarkers for Diagnosis and Treatment Monitoring and Treatment Targets · Luxembourg Institute of Health
- Dec 2026Endophenotyping for Plant-based Food Allergy Diagnosis, Tolerance Biomarkers, and Mechanisms in Microneedle Immunotherapy · Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
- Dec 2026Steroid Use in Treatment of Allergic Reactions to Food · Johannes Trueck
Who these studies take
Of the 52 Food Hypersensitivity studies recruiting now, 8 (15%) set no upper age limit and 40 (77%) stop at 75 or younger. 45 (87%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 16 (31%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 35 (67%) | 35 (67%) |
| 18 | 26 (50%) | 26 (50%) |
| 30 | 23 (44%) | 23 (44%) |
| 40 | 22 (42%) | 22 (42%) |
| 50 | 22 (42%) | 22 (42%) |
| 65 | 17 (33%) | 17 (33%) |
| 75 | 12 (23%) | 12 (23%) |
| 85 | 11 (21%) | 11 (21%) |
Across all 376 studies, recruiting or not: 79% stop at 75 or younger and 76% at 65; 78% take children; 2% are for women only and 0% for men only; 30% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Food Hypersensitivity studies take
Of 19 phase 2 interventional studies under Food Hypersensitivity, half reached primary completion within 46 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 46 mo19–71 · 19 studies | — | — |
| Interventional, no phase | 29 mo13–50 · 84 studies | — | 29 mo13–50 · 81 studies |
| Observational | 42 mo19–250 · 43 studies | — | 42 mo19–250 · 42 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Oral Food Challenge After One to Two Doses of Omalizumab Treatment for Food AllergyOct 28, 2026NCT07845552
Newly registered5
- Evaluating Sucrose and Cold Oral Interventions for the Treatment of Oral Pruritus During Allergy Procedures.Nov 4, 2026NCT07917312
- The Impact of Proton-pump Inhibitors on Threshold Dose DistributionsOct 28, 2026NCT07902440
- Immunotherapy for Curing Toddlers With Severe Food Allergy - a Paradigm Shift From Passive to Active Treatment With Multi-allergen Oral ImmunotherapyOct 27, 2026NCT07899359
- Oral Immunotherapy for Children With Peanut AllergyOct 26, 2026NCT07895095
- Oral Immunotherapy for Children With Egg AllergyOct 22, 2026NCT07888439
Studies
Recruiting first, then most recently updated. Showing 50 of 376. Browse all 376 → or search them.
- Natural History and Genetics of Food Allergy and Related ConditionsRecruitingNCT025048531 country
- Michigan Food and Atopic Dermatitis (M-FAD) Program - Molecular Analytics ProjectRecruitingNCT06300697Not applicable1 country
- A 52-week Study of Remibrutinib in IgE-mediated Food AllergyRecruitingNCT07768371Phase 31 country
- Observational Study of IgE-Mediated Leguminous Allergies in a Pediatric PopulationNot yet recruitingNCT078111411 country
- Evaluating Sucrose and Cold Oral Interventions for the Treatment of Oral Pruritus During Allergy Procedures.Not yet recruitingNCT07917312Not applicable1 country
- Rapid Escalation Oral Immunotherapy to Achieve Remission in Children With Cashew AllergyNot yet recruitingNCT07868731Not applicable
- Oral Food Challenge After One to Two Doses of Omalizumab Treatment for Food AllergyRecruitingNCT07845552Phase 41 country
- Immunotherapy for Curing Toddlers With Severe Food Allergy - a Paradigm Shift From Passive to Active Treatment With Multi-allergen Oral ImmunotherapyNot yet recruitingNCT07899359Not applicable
- Oral Immunotherapy for Children With Peanut AllergyNot yet recruitingNCT07895095Not applicable1 country
- Study of Oral Food Challenge Biomarkers (SAFER)RecruitingNCT072794671 country
- Oral Immunotherapy for Children With Egg AllergyNot yet recruitingNCT07888439Not applicable1 country
- UNC Cashew Sublingual ImmunotherapyNot yet recruitingNCT07170540Phase 21 country
- SHAPE Trial: Skin Health and Allergy Prevention ExposureRecruitingNCT07489040Not applicable1 country
- Food Introduction for Risk Reduction, Support Tolerance: Behavioral Intervention for Toddler Eating SuccessNot yet recruitingNCT07857057Not applicable1 country
- Molecular Basis of Food AllergyEnrolling by invitationNCT018323241 country
- Recombinant Tropomyosin- and Hemocyanin-Specific IgE in Children With Suspected Shrimp AllergyRecruitingNCT07501325Not applicable1 country
- A Randomized Controlled Trial of Oral Immunotherapy Versus Allergen Avoidance in Children Under 2 Years With Food AllergyNot yet recruitingNCT07825662Not applicable1 country
- A Study to Evaluate the Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Characteristics of LP-003 Injection in Participants With Wheat AllergyNot yet recruitingNCT07816432Phase 21 country
- Non-Immunoglobulin E-mediated Food Allergies in ChildrenRecruitingNCT044629781 country
- The Role of NIchel and LTPs Sensitization in Functional Gastrointestinal Disorders: the NILT StudyRecruitingNCT071058651 country
- GOAt Milk Formula-based Ladder Versus Cow's Milk LadderNot yet recruitingNCT07795957Not applicable1 country
- Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic DermatitisRecruitingNCT03835767Phase 21 country
- Flow CAST® Peanut TrialNot yet recruitingNCT07775430
- Oral Immunotherapy for Children With Cow's Milk AllergyNot yet recruitingNCT07768696Not applicable1 country
- Multi-Food Oral Immunotherapy for Peanut and Tree NutsNot yet recruitingNCT07764159Not applicable1 country
- FASC: Fish Allergy in Spanish Children - A Study of New Cases of Fish Allergy in Children and AdolescentsNot yet recruitingNCT07727148
- Prescreening Protocol to Enroll in Food Allergy Clinical Studies at a Single SiteRecruitingNCT035396921 country
- Early Introduction and Sustained Ingestion (EISI) Using Two Educational Opportunities in InfantsRecruitingNCT07321522Not applicable1 country
- Expanded Access of Dupilumab in Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy Previously Treated With LinvoseltamabAvailableNCT06631677
- Omalizumab for the Treatment of Food Allergy in Patients With Elevated Total IgE LevelsRecruitingNCT06934200Phase 21 country
- Pathway to Peanut ToleranceRecruitingNCT07592780Not applicable1 country
- Predictors of Persistent Peanut Allergy at Age 5 YearsEnrolling by invitationNCT02497261
- Boiled Tree Nut for Oral Immunotherapy in Food-allergic ChildrenRecruitingNCT06467994Phase 21 country
- EmoTIChealth: Promoting Adolescent Health Through a Serious Game.RecruitingNCT07212530Not applicable1 country
- Stepwise Heat-Denaturated Protein Introduction for Tolerance Induction in Food AllergyRecruitingNCT06380673Not applicable1 country
- Oral Immunotherapy With Egg in InfantsNot yet recruitingNCT07540091
- Comparison of Skin Prick Testing, Extract-specific IgE Antibody Testing and Component Resolved Diagnosis in Diagnosing of Legume AllergyRecruitingNCT069238781 country
- Tolerance Results and Immune Mechanisms in Cow´s Milk and/or Hen´s Egg Allergic Children Following Natural Evolution or Oral ImmunotherapyRecruitingNCT07419243Phase 1/21 country
- Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic DiseasesRecruitingNCT06529913Not applicable1 country
- Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO StudyRecruitingNCT06976775Phase 2/31 country
- Omalizumab Weight-Based Dosing Efficacy TrialRecruitingNCT06943534Phase 21 country
- Allergy and Immunology Natural History StudyRecruitingNCT055844881 country
- A Long Term, Observational Follow-Up Study of Children and Young People Who Underwent an 18-Month Course of Oral Immunotherapy Treatment for Peanut, Egg or Milk Allergy (5-15 Years Post-Treatment)RecruitingNCT073591831 country
- Steroid Use in Treatment of Allergic Reactions to FoodRecruitingNCT07341776Phase 41 country
- SMASH: Study to Evaluate the Clinical Efficacy of an Extensively Hydrolysed Infant Formula With Synbiotics and a Human Milk Oligosaccharide (HMO) in Infants With Cow's Milk Protein Allergy (CMPA)RecruitingNCT073426211 country
- Trophallergen Prick Tests (PT) : Influence of Food Sample Shelf Life on the Reproducibility of PT ResultsRecruitingNCT06872996Not applicable1 country
- Analysis of the Prevalence of Sensitization to Plants Containing Gibberellins Using Realistic Skin Prick TestsRecruitingNCT06183398Not applicable1 country
- Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic DisordersRecruitingNCT002675011 country
- Oral Immunotherapy in Young Children With Food AllergyEnrolling by invitationNCT05738798Not applicable1 country
- Sustained Unresponsiveness (SU) to Cashew Nut Protein Following Oral Allergen-Specific ImmunotherapyNot yet recruitingNCT07158619Not applicable1 country