An interventional study of MAKO Robotic System (Stryker, USA) and Conventional Total Hip Arthroplasty in Osteo Arthritis Knee and Hip, sponsored by Hamilton Health Sciences Corporation. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-30.
Sponsored by Hamilton Health Sciences Corporation · Not applicable, Interventional, and Treatment
Hip replacement is highly effective for severe osteoarthritis, but some patients continue to experience symptoms or complications. Robotic-assisted hip replacement uses three-dimensional planning and robotic guidance to position implants more precisely. Although its use is increasing, it remains uncertain whether this added precision improves recovery or outcomes that patients can feel.
We will conduct an internal pilot randomized trial of adults undergoing hip replacement at Juravinski Hospital. Participants will be assigned by chance to robotic-assisted or conventional surgery. The pilot will assess recruitment, delivery of assigned surgery, protocol adherence, follow-up and data quality to determine whether a larger Canadian multicentre trial is feasible. We will also collect joint awareness, function, quality of life, satisfaction, complications, operating time, length of stay and readmission. If progression criteria are met, pilot participants and data will be retained in the expanded trial. This study will build the Canadian evidence needed to evaluate robotic-assisted hip replacement responsibly.
Hamilton Health Sciences Corporation is the lead sponsor of 242 studies on the registry; 38 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
MAKO Robotic System (Stryker, USA)
Procedure: MAKO Robotic System (Stryker, USA)
Conventional Total Hip Arthroplasty
Procedure: Conventional Total Hip Arthroplasty
Stryker MAKO Robotic System using Stryker Implants
Also known as: Conventional Total Hip Arthroplasty
Conventional Total Hip Arthroplasty
Feasibility Outcomes
Recruitment, allocated intervention, and protocol adherence, completion of follow-up among those due, and key data completeness.
Time frame: 6 months
Forgotten Joint Score-12 (FJS-12)
Awareness of the operated hip during everyday activities will be assessed using the 12-item Forgotten Joint Score. Responses are converted to a total score ranging from 0 to 100. Higher scores indicate less awareness of the artificial joint and a better outcome.
Time frame: 6 weeks and 6 months after surgery.
Oxford Hip Score (OHS)
Hip pain and function will be assessed using the Oxford Hip Score, a 12-item patient-reported questionnaire. Item scores are summed to produce a total score ranging from 0 to 48. Higher scores indicate less pain and better hip function.
Time frame: 6 weeks and 6 months after surgery.
Euro-Qol 5 Dimensions (EQ-5D)
Health-related quality of life will be assessed using the EuroQol 5-Dimension 5-Level questionnaire. It assesses five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Each dimension has five response levels, coded from 1 (no problems) to 5 (extreme problems or inability to perform the activity). Higher levels indicate worse health within that dimension.
Time frame: 6 weeks and 6 months after surgery.
Patient Satisfaction With Hip Replacement
Overall satisfaction with the operated hip will be assessed using five response categories: very satisfied, satisfied, neither satisfied nor dissatisfied, dissatisfied, or very dissatisfied. The number and percentage of participants in each category will be reported.
Time frame: 6 weeks and 6 months after surgery.
Surgical Complications
Prespecified complications include intraoperative or postoperative periprosthetic fracture, superficial or deep surgical site infection, prosthetic dislocation, implant failure or aseptic loosening, and reoperation. Other clinically important surgical complications will also be recorded.
Time frame: 6 weeks and 6 months after surgery.
Safety Outcomes
Any adverse or serious adverse events will be collected where applicable for trial monitoring.
Time frame: 6 weeks and 6 months after surgery.
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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