An interventional study of Temperature and Humidity in Environmental Exposure, Temperature Change, Body and Condition, sponsored by Maastricht University Medical Center. Completed at 1 site in Netherlands. Open to participants aged 20 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-03-24.
Sponsored by Maastricht University Medical Center · Not applicable, Interventional, and Other
The goal of this study is to learn about the effect of heat and humidity on cognition and health. The main question[s] it aims to answer are:
type of study: interventional participant population: 20-40years, both gender, healthy Participants will be exposed for 4 different sessions of 8 hours at a time, to 32˚ C or 25˚ C in combination with relative humidity of 30 %RH or 70 %RH.
Overall, the project aims to evaluate the effects of high vs. neutral temperature (32˚ C vs. 25˚ C) in combination with high vs. low humidity (30 %RH vs. 70 %RH) on cognition, for longer exposure duration (8 hours). Deviations from the personal comfort zones are expected to affect both subjective feelings and physiological parameters. Therefore, the following parameters will be included: cognition, environmental perception, energy expenditure, body temperatures.
Main research question and primary objective:
What is the impact of being exposed for 8 hours to a high humidity (RH 70%) versus low humidity (RH 30%) on cognitive performance of individuals if the room temperature is 25ºC or 32ºC?
This leads to the following hypotheses:
Secondary research question and secondary objective:
What is the effect of high vs. neutral temperature (32˚ C vs. 25˚ C) in combination with high vs. low humidity (30 %RH vs. 70 %RH) on physiological responses, environmental perception, decision making, and bias behaviour?
This leads to the following hypotheses:
What are the effects of higher humidity on environmental perception (thermal, air quality, moisture/wetness) comfort, perception, and sensation?
Exploratory research question and objective:
What is the interaction effect of high vs. neutral temperature (32˚ C vs. 25˚ C) in combination with high vs. low humidity (30 %RH vs. 70 %RH) on cognitive performance, physiological responses, environmental perception, decision making, and bias behaviour?
97 studies on the registry are indexed under Body Temperature Changes; 20 are open to participants now.
This study's enrollment of 22 is below the median of 40 across 68 interventional studies indexed under Body Temperature Changes.
Browse Body Temperature Changes studies →Maastricht University Medical Center is the lead sponsor of 853 studies on the registry; 114 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraception
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
32C or 25C and 30%RH or 70%RH
Other: Temperature and Humidity
Temperature and Humidity of room changed
Cognition
Using a tablet based cognitive test battery
Time frame: 1 month
Heart Rate (bpm)
Heart Rate measured using Polar heart rate belt in (bpm) with RR and ECG data extracted
Time frame: 1 month
Blood pressure (mmHg)
Blood pressure - both systolic and diastolic pressures measured hourly using an automated blood pressure monitor and cuff
Time frame: 1 month
Metabolic Rate (ml O2//min/kg)
Metabolic rates measured through whole room calorimetry
Time frame: 1 month
Skin Temperature (C)
Skin temperature measured using thermochron (ibuttons) at multiple sites
Time frame: 1 month
Body Core Temperature (C)
Core Temperature measured via telemetric pill ingested in the morning
Time frame: 1 month
Room Temperature (C)
Environmental measures are measured continuously using temperature specific sensors in the room
Time frame: 1 month
Humidity (%)
Environmental measures are measured continuously using humidity specific sensors in the room
Time frame: 1 month
Plan to share: Yes — If requested raw data will be provided.
Supporting information: Study protocol, Statistical analysis plan, Analytic code
Time frame: Ongoing, depends on the request.
Access criteria: Official request made stating the purpose of use for the data. Only individuals that consent to their data to be used in further analysis will be shared.
No publications or documents are linked to this record.
This study is completed, as verified in Sep 2023. You cannot join it, but the record below documents what was studied.
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