An observational study in Diverticular Disease of Colon, Diverticulitis, Colonic and Peritonitis, sponsored by Uppsala University Hospital. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-06-07.
Sponsored by Uppsala University Hospital · Observational
The goal of this observational study is to study the emergency surgical treatment of diverticular disease in Sweden outside clinical trials. The main questions it aims to answer are:
Researchers will compare the different methods to see if there is a surgical operation that is superior for the treatment of acute diverticulitis.
A retrospective study of patients who were admitted to a Swedish hospital between 1st July 2014 and 31st December 2020 with an ICD-10 code for diverticular disease of the large intestine (K57.2- K57.9) will be included. Patients who underwent procedures relevant to diverticulitis will be identified and therefore will be included. Procedures will be grouped into two categories: Laparoscopic peritoneal lavage (Group I), and sigmoid resection with or without stoma (Group II).
The cohort will be studied from 1st January 1997 until the index date aiming to assess comorbidities, previous abdominal surgeries, and admissions for diverticular disease. A Charlson Comorbidity Index (CCI) system adjusted for Swedish ICD-10 version will be used to calculate a composite score to reflect comorbidity.
27 studies on the registry are indexed under Diverticulitis, Colonic; 8 are open to participants now.
This study's enrollment of 52,863 is above the median of 250 across 15 observational studies indexed under Diverticulitis, Colonic.
Browse Diverticulitis, Colonic studies →Uppsala University Hospital is the lead sponsor of 73 studies on the registry; 19 are open to participants now.
Compared within Diverticulitis, Colonic, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Diverticulosis, Colonic. The counts are of registry records indexed under each term, refreshed daily. How we classify →
The study will be based on a national cohort gathered from National Patient Register, the National Cancer Register and the Cause of Death Register, obtained by the Swedish National Board of Health and Welfare.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Preferred operation for acute colonic diverticular disease
Laparoscopic peritoneal lavage or sigmoid resection
Time frame: Up to 78 months
Crossover surgery
Crossover from laparoscopy to resection surgery
Time frame: 1 day
Reoperation
Disease- associated reoperations involving the bowel or abdominal wall
Time frame: From date of inclusion until the date of the end of study or date of death from any cause, whichever came first, assessed up to 78 months
Overall survival
Time frame: From date of inclusion until the date of the end of study or date of death from any cause, whichever came first, assessed up to 78 months
Postoperative length of hospital stay
Time frame: From date of inclusion until the date of discharge, assessed up to 78 months
Colorectal cancer diagnosis
Time frame: From date of inclusion until the date of the end of study or date of death from any cause, whichever came first, assessed up to 78 months
Thirty-day postoperative mortality
Time frame: Up 30 days
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in May 2023. You cannot join it, but the record below documents what was studied.
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Uppsala University Hospital