An observational study in Healthy Controls Without Orthostatic Hypotension, sponsored by Fujian Medical University Union Hospital. Status unknown at 1 site in China. Open to participants aged 30 Years to 80 Years. Per ClinicalTrials.gov, last updated 2023-04-20.
Sponsored by Fujian Medical University Union Hospital · Observational
Background: In recent years, the changes of cognitive function in mild cognitive impairment have attracted attention.
Methods/design: We will follow up at 3. The primary outcome will be the measurement of cognitive function using neuropsychological assessment scales such as MOCA, MMSE, etc... Minor variables will be included plasma biomarkers (Aβ, Tau, GFAP, etc.), multimodal brain electrophysiology (P300, VP300, heart rate variability, etc.), and neuroimaging indicators (NODDI).
155 studies on the registry are indexed under Hypotension, Orthostatic; 34 are open to participants now.
This study's planned enrollment of 200 is above the median of 50 across 34 observational studies indexed under Hypotension, Orthostatic.
Browse Hypotension, Orthostatic studies →Fujian Medical University Union Hospital is the lead sponsor of 100 studies on the registry; 72 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Chinese who met the inclusion and exclusion criteria
Exclusion Criteria:
Other: observational study
observational study
Changes in Montreal Cognitive Assessment (MoCA) scores after 3 months.
The MOCA scale scores range from 0 to 30, with higher scores indicating better cognition
Time frame: Participants will be followed up for 3 months after baseline.
Changes in Plasma amyloid protein levels after 3 months.
Plasma amyloid protein(ug/ml) is an important indicator of cognitive function.
Time frame: Participants will be followed up for 3 months after baseline.
Changes in Plasma tau levels after 3 months.
Plasma tau(ug/ml) is an important indicator of cognitive function
Time frame: Participants will be followed up for 3 months after baseline.
Changes in Blood pressure (mmHg) after 3 months.
An experienced physician will measure blood pressure on the right upper arm after the subject rest for 5 min, taking the average of the two measurements as the final result.
Time frame: Participants will be followed up for 3 months after baseline.
Plan to share: Yes
Supporting information: Study protocol, Sap, Icf, Csr, Analytic code
This study is status unknown, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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Fujian Medical University Union Hospital