An interventional study of Virtual Reality Tool in Substance Use Disorders and HIV Infections, sponsored by Medical University of South Carolina. Active, not recruiting at 1 site in United States. Open to participants aged 15 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-20.
Sponsored by Medical University of South Carolina · Not applicable, Interventional, and Treatment
Among 48 studies in Substance-Related Disorders by Medical University of South Carolina — 7 open to participants now, 10 under way, none of them phase 3. Substance-Related Disorders · Medical University of South Carolina.
Among the 48 studies in Substance-Related Disorders by Medical University of South Carolina, this one is the 33rd largest by planned enrollment of the 47 interventional ones, is one of 4 that started in 2025, is one of 24 with no phase, and was the 40th registered.
2,238 studies on the registry are indexed under Substance-Related Disorders; 409 are open to participants now.
This study's planned enrollment of 50 is below the median of 108 across 1,840 interventional studies indexed under Substance-Related Disorders.
Browse Substance-Related Disorders studies →7 of the 48 studies in Substance-Related Disorders by Medical University of South Carolina are open now, in 1 country. Each count lists the studies.
Of the 266 Substance-Related Disorders studies recruiting now, 130 (49%) set no upper age limit and 118 (44%) stop at 75 or younger; 56 take children under 18; 89 take healthy volunteers.
This study: 15 Years to 30 Years · all sexes · healthy volunteers too.
The full table on the hub →48 studies; the count open now beside each. This study's row is marked.
First in 1992; this study’s year is marked. 4 started in 2025.
Median enrollment 81 across the 47 interventional studies, 24 across the 1 observational. Of the 37 that completed or were terminated, 18 (49%) have results posted.
Medical University of South Carolina is the lead sponsor of 874 studies on the registry; 166 are open to participants now.
Of its 131 completed or terminated interventional studies of FDA-regulated products, 104 (79%) have results posted.
4 of the studies in Substance-Related Disorders by Medical University of South Carolina that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT04998916Medical University of South CarolinaMPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience | 2026-12-31 |
| NCT05384223Medical University of South CarolinaEvaluation of RRFT for Co-occurring SUD and PTSD Among Teens | 2027-02-28 |
| NCT05764213Medical University of South CarolinaImproving Maternal Mental Health & SUD Screening and Treatment | 2027-07-31 |
| NCT06641115Medical University of South CarolinaIntegrated Treatment for Opioid Use Disorder and PTSD | 2027-08 |
Among the 48 studies in Substance-Related Disorders by Medical University of South Carolina, from their registry updates:
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance abuse risk behavior among at-risk young people who have experienced psychosocial trauma. Participants eligible for this study include young men who have sex with men (YMSM)/individuals who are romantically/physically attracted to men and adolescents with substance use disorder (SUD) between the ages of 15 - 30 and have experienced at least one traumatic event in their lifetime. Frontline healthcare workers who work within these populations are eligible for the study as well.
YMSM and adolescents with SUD participants will complete 3 study sessions. During session 1, informed consent and baseline measures are administered. Approximately one week later, during session 2, participants use and assess the virtual reality tool. Approximately one week later, during session 3, baseline assessments are re-administered.
Inclusion Criteria for YMSM are as follows:
Inclusion Criteria for adolescents with SUD are as follows:
Inclusion Criteria for front line healthcare workers are as follows:
Exclusion Criteria for all participants are as follows:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
All participants will receive the same intervention
Behavioral: Virtual Reality Tool
Virtual Reality Tool for At-Risk Trauma-Exposed Young People
Quantity and Frequency of Substance Use
The Timeline Follow Back (TLFB) is a validated, subjective measure that uses a calendar for people to provide estimates of substance use (drugs/alcohol) on a daily basis, retrospectively. Key dates and calendars are used to aid in memory recall. The measure is beneficial in both clinical and research environments. Over time, the TLFB looks for a decrease in substance use. Higher numbers of substance use are indicative of greater substance use.
Time frame: Day 0 (Session 1) up to Day 14 (Session 3)
PDFs hosted by the registry, ClinicalTrials.gov.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is active, not recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Medical University of South Carolina →