An interventional study of antihypertensive drug treatment in High Blood Pressure, sponsored by Centre Hospitalier de Cayenne. Not yet recruiting. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-04-14.
Sponsored by Centre Hospitalier de Cayenne · Not applicable, Interventional, and Prevention
The main objective is to implement of a community-based primary care intervention against high blood pressure. We want to show that this intervention decreases the incidence of stroke in the community of agglomerations of the central coast of French Guiana, with a rapid effectiveness of about -30% at 2 years.
The hypothesis of the research is that, thanks to a strategy of early detection of hypertension based on "outreach" by community relays, it will be possible to increase the effectiveness of primary prevention among the precarious population (early treatment, access to healthcare, improvement of therapeutic follow-up, reduction of renunciations and interruptions of treatment). This strategy, adapted to the Guianese context, would make it possible to reduce the incidence and mortality of cardiovascular diseases among the most vulnerable people, particularly stroke. Such data would be a prerequisite for a more ambitious strategy, aiming to implement policies on a sufficient scale policies on a scale and intensity sufficient to have an impact on the problem of social inequalities in health other than those related to high blood pressure.
The quasi-experimental before-and-after methodology makes it possible to compare, on a population basis, a quantitative endpoint - in this case the number of strokes - between before and after the implementation of a public health intervention. For reasons of acceptance by the partners, statistical power, and potential bias, a before-and-after design seems more interesting.
It will be a pre-screening of hypertension, a possible referral for medical care or opening of health care rights and health education through hygienic and dietary advice and health prevention focused on hypertension.
6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.
This study's planned enrollment of 50,000 is above the median of 90 across 4,995 interventional studies indexed under Hypertension.
Browse Hypertension studies →Centre Hospitalier de Cayenne is the lead sponsor of 47 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
diagnosis and treatment of high blood pressure
Drug: antihypertensive drug treatment
Patients with hypertension will be treated for it by their physician
To compare the incidence of stroke between before and after the start of the intervention according to PMSI data in resident persons in the agglomeration community of the central coast of French Guiana.
To compare the incidence of stroke between before and after the intervention
Time frame: 5 years
The incidence of acute coronary syndrome (ACS), transient ischemic attack, lower extremity arterial disease, aneurysm and end stage renal disease treated.
Time frame: comparison between before (over 5 years) and 1, 2 and 3 years after the beginning of the intervention according to PMSI data in the neighborhoods
Stroke incidence
Time frame: comparison between before (over 5 years) and 1, 2 and 3 years after the beginning of the intervention according to PMSI data in the neighborhoods
treatment adherence
lickert scale (5 levels)
Time frame: Inclusion
Number of systolic and diastolic blood pressure measurements performed, number of new diagnoses and number of rediscoveries among those lost to follow-up during the intervention (number of people who give up on diagnosis or medical care)
Time frame: 2 years
Quantification of the evolution of the prescription of antihypertensive drugs in Guiana via data from the Social Security
Time frame: Before and 1, 2, and 3 years after the implementation of the intervention
stroke in hospital case fatality
Time frame: 1, 2, and 3 years after the start of the intervention
No study locations are listed for this record.
Plan to share: Undecided
This study is not yet recruiting, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier de Cayenne