An interventional study of Support2Quit App - Cognitive Dissonance Based Smoking Cessation + Smoking Cessation Tips and Tips for Smoking Cessation App in Tobacco Use, sponsored by Oregon Research Behavioral Intervention Strategies, Inc.. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-11-24.
Sponsored by Oregon Research Behavioral Intervention Strategies, Inc. (part of Influents Innovations) · Not applicable, Interventional, and Treatment
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Among 311 studies in Tobacco Use with a site in United States — 52 open to participants now, 63 under way, 1 of them phase 3. Tobacco Use · United States.
Among the 311 studies in Tobacco Use with a site in United States, this one is the 67th largest by enrollment of the 286 interventional ones that give a count, is one of 21 that started in 2023, is one of 231 with no phase, and was the 242nd registered.
421 studies on the registry are indexed under Tobacco Use; 83 are open to participants now.
Browse Tobacco Use studies →52 of the 311 studies in Tobacco Use with a site in United States are open now. Recruiting first, the newest first:
RAI Services Company · Sites in United States
Ages 21–65 · Healthy volunteers
University of Pennsylvania · Sites in United States
Ages 18+
RAI Services Company · Sites in United States
Ages 21–65 · Healthy volunteers
University of Pittsburgh · Sites in United States
Ages 18+ · Women only
RAI Services Company · Sites in United States
Ages 21–65 · Healthy volunteers
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 50 Tobacco Use studies recruiting now, 28 (56%) set no upper age limit and 18 (36%) stop at 75 or younger; 2 take children under 18; 27 take healthy volunteers.
This study: 18 Years and older · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
311 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 25 · Phase 2 22 · Phase 3 10 · Phase 4 9
First in 1992; this study’s year is marked. 21 started in 2023.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 437 is above the median of 127 across 352 interventional studies indexed under Tobacco Use.
Median enrollment 120 across the 286 interventional studies, 174 across the 24 observational. Of the 232 that completed or were terminated, 82 (35%) have results posted.
This tab as a report to print or save as PDF → With an account.
67 of 311 have an industry lead sponsor. The 10 most frequent:
This study is registered under Oregon Research Behavioral Intervention Strategies, Inc., one of the names counted as Influents Innovations. Under that name alone:
Oregon Research Behavioral Intervention Strategies, Inc. is the lead sponsor of 24 studies on the registry; 3 are open to participants now.
Influents Innovations has 2 studies filed under Tobacco Use — fewer than ten, so there is no comparison to draw.
30 of the studies in Tobacco Use with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT05707871Wake Forest University Health SciencesCardiovascular Effects of Very Low Nicotine Content Cigarettes | 2026-12 |
| NCT07710820RAI Services CompanyA Multi-Site Study to Assess the Effect of Availability of a Heated Tobacco Product on Smoking Abstinence Among Current Primary Cigarette Smokers | 2026-12 |
| NCT05445804Johns Hopkins UniversityOral Cannabidiol for Tobacco Cessation | 2026-12-01 |
| NCT07598136RAI Services CompanyA Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers | 2026-12-17 |
| NCT04297592Mayo ClinicAntibiotic Prophylaxis in High-Risk Arthroplasty Patients | 2027-01 |
Add all 30 to your calendar (.ics) → With an account.
Among the 311 studies in Tobacco Use with a site in United States, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This research study aims to develop a cognitive dissonance-based mobile app for smoking cessation (Support2Quit) and test the efficacy of the app with 500 adult smokers who express a desire to quit smoking.
This research project will evaluate the Support2Quit mobile app for smoking cessation by having 500 daily adult smokers recruited through social media and randomized to either the Support2Quit app or an app that has similar content but no tasks for inducing cognitive dissonance among participants. Outcomes will be measured at 1- and 3-months post-baseline and will include quit attempts, number of days without smoking (smoke free days), and changes in smoking attitudes and behavior, and smoking abstinence. Usability data, system log data on program use, and participant satisfaction data will also be analyzed.
The researchers hypothesize that individuals using the cognitive dissonance intervention (CDI) will show greater increases in quit attempts, smoke free days, quit rates, and positive smoking attitudes and behaviors than individuals in the active comparison condition. The researchers will test whether gender, smoking dependence, readiness to quit, previous quit attempts, age of smoking initiation, and socio-economic status moderate intervention effects on smoking outcomes.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion criteria:
This group will receive daily smoking cessation tips and will be asked to complete activities within the app that are designed to induce cognitive dissonance, create and share videos related to the activities with an online group, and provide support to other group members
Behavioral: Support2Quit App - Cognitive Dissonance Based Smoking Cessation + Smoking Cessation Tips
This group will use an app that consists of tips for quitting cigarettes but does not include the cognitive dissonance component.
Behavioral: Tips for Smoking Cessation App
Support2Quit App (Cognitive Dissonance Based Smoking Cessation) Use of the Support2Quit app, completion of cognitive dissonance activities, sharing of videos with online group, and providing support to other group members
App containing daily tips for smoking cessation
Number of Participants With Cigarette Abstinence
Based on 1-item that asked "In the past 7 days, have you smoked any cigarettes?". The variable is coded 1 if they the participants indicated they did not smoke any cigarettes otherwise coded 0. A value of 1 = abstinence and 0 = not abstinent.
Time frame: 1-month and 3-month follow-up
Fagerstrom Tobacco Dependence Scale
This is a 6 item measure of tobacco dependence and response options are a mix of ordered categorical and dichotomous items. Item 1 "How many cigarettes per day to you smoke?" (0 = less than 10 cigarettes a day, 3 = 31 or more cigarettes a day). Item 2 "How soon after you wake do you smoke your first cigarette (0 = after 60 minutes, 3 = within 5 minutes). Item 3 "Is it hard to keep from smoking in places where it is prohibited (1 = yes, 0 = no). Item 4 "Which cigarette would you hate to give up most (1 = the first in the morning, 0 = any other). Item 5 "Do you smoke more cigarettes during the first 2 hours of the day compared to the rest of the day (1 = yes, 0 = no). Item 6 "Do you smoke when you are so ill you are in bed?" (1 = yes, 0 = no). A total sum score is computed and can range from 0 to 10 points with higher scores indicating higher levels of tobacco dependence.
Time frame: Baseline, 1-month follow-up, 3-month follow-up
Number of Participants With Reduction in Number of Cigarettes Smoked Per Day
Represents whether or not (1 = yes, 0 = no) a reduction of cigarettes smoked per day is reported from the baseline assessment. A higher score indicates a reduction in cigarettes smoked.
Time frame: 1-month and 3-month follow-up
Number of Participants With Reduction in the Number of Cigarettes Smoked Per Day and Reduced to 0-5 Cigarettes
Represents whether or not (1 = yes, 0 = no) a reduction of cigarettes smoked per day is reported from the baseline assessment and is the number of daily cigarettes in 0-5 per day. A higher score indicates a reduction in cigarettes smoked per day and the number smoked is 5 or less.
Time frame: 1-month and 3-month follow-up
| Milestone | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support without Cognitive Dissonance Activities |
|---|---|---|
| Started | 292 | 145 |
| Completed | 259 | 133 |
| Not completed | 33 | 12 |
| Withdrew: Lost to follow-up | 33 | 12 |
Based on 1-item that asked "In the past 7 days, have you smoked any cigarettes?". The variable is coded 1 if they the participants indicated they did not smoke any cigarettes otherwise coded 0. A value of 1 = abstinence and 0 = not abstinent.
| Participants | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support without Cognitive Dissonance Activities |
|---|---|---|
| 1-Month Follow-Up | 102 | 38 |
| 3-Month Follow-Up | 112 | 54 |
This is a 6 item measure of tobacco dependence and response options are a mix of ordered categorical and dichotomous items. Item 1 "How many cigarettes per day to you smoke?" (0 = less than 10 cigarettes a day, 3 = 31 or more cigarettes a day). Item 2 "How soon after you wake do you smoke your first cigarette (0 = after 60 minutes, 3 = within 5 minutes). Item 3 "Is it hard to keep from smoking in places where it is prohibited (1 = yes, 0 = no). Item 4 "Which cigarette would you hate to give up most (1 = the first in the morning, 0 = any other). Item 5 "Do you smoke more cigarettes during the first 2 hours of the day compared to the rest of the day (1 = yes, 0 = no). Item 6 "Do you smoke when you are so ill you are in bed?" (1 = yes, 0 = no). A total sum score is computed and can range from 0 to 10 points with higher scores indicating higher levels of tobacco dependence.
| units on a scale | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support without Cognitive Dissonance Activities |
|---|---|---|
| Baseline | 5.7 ± 2.0 | 5.4 ± 1.9 |
| 1-Month Follow-Up | 4.1 ± 2.4 | 4.4 ± 2.2 |
| 3-Month Follow-Up | 4.0 ± 2.1 | 4.2 ± 2.4 |
Represents whether or not (1 = yes, 0 = no) a reduction of cigarettes smoked per day is reported from the baseline assessment. A higher score indicates a reduction in cigarettes smoked.
| Participants | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support without Cognitive Dissonance Activities |
|---|---|---|
| 1-Month Follow-Up | 191 | 91 |
| 3-Month Follow-Up | 218 | 110 |
Represents whether or not (1 = yes, 0 = no) a reduction of cigarettes smoked per day is reported from the baseline assessment and is the number of daily cigarettes in 0-5 per day. A higher score indicates a reduction in cigarettes smoked per day and the number smoked is 5 or less.
| Participants | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support without Cognitive Dissonance Activities |
|---|---|---|
| 1-Month Follow-Up | 144 | 56 |
| 3-Month Follow-Up | 165 | 74 |
Collected over Data was collected from the baseline assessment to the 3 month post-baseline follow up assessment.. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Support2Quit App - Cognitive Dissonance Based Smoking Cessation | 0/292 (0%) | 0/292 (0%) | 0/292 (0%) |
| Comparison App - Smoking Cessation App without Cognitive Dissonance Activities | 0/145 (0%) | 0/145 (0%) | 0/145 (0%) |
| Age, Continuous(years) | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support Without Cognitive Dissonance Activities | Total |
|---|---|---|---|
| Mean | 49.21 ± 12.00 | 48.84 ± 11.50 | 49.08 ± 11.82 |
| Sex/Gender, Customized(Participants) | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support Without Cognitive Dissonance Activities | Total |
|---|---|---|---|
| Female | 215 | 104 | 319 |
| Male | 76 | 38 | 114 |
| Transgender | 1 | 1 | 2 |
| Non-binary | 0 | 2 | 2 |
| Ethnicity (NIH/OMB)(Participants) | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support Without Cognitive Dissonance Activities | Total |
|---|---|---|---|
| Hispanic or Latino | 17 | 12 | 29 |
| Not Hispanic or Latino | 275 | 133 | 408 |
| Unknown or Not Reported | 0 | 0 | 0 |
| Race (NIH/OMB)(Participants) | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support Without Cognitive Dissonance Activities | Total |
|---|---|---|---|
| American Indian or Alaska Native | 6 | 3 | 9 |
| Asian | 5 | 1 | 6 |
| Native Hawaiian or Other Pacific Islander | 1 | 0 | 1 |
| Black or African American | 32 | 13 | 45 |
| White | 224 | 119 | 343 |
| More than one race | 0 | 0 | 0 |
| Unknown or Not Reported | 24 | 9 | 33 |
| Region of Enrollment(participants) | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support Without Cognitive Dissonance Activities | Total |
|---|---|---|---|
| United States | 292 | 145 | 437 |
| Highest level of education(Participants) | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support Without Cognitive Dissonance Activities | Total |
|---|---|---|---|
| Did not graduate high school | 12 | 1 | 13 |
| High school graduate | 63 | 23 | 86 |
| Some college, no degree | 91 | 44 | 135 |
| Technical school or associate degree | 52 | 36 | 88 |
| Bachelor's degree | 52 | 34 | 86 |
| Master's degree | 17 | 6 | 23 |
| Doctorate | 4 | 1 | 5 |
| Declined to answer | 1 | 0 | 1 |
| Annual household income(Participants) | Support2Quit App - Cognitive Dissonance Based Smoking Cessation | Comparison App - Smoking Cessation Support Without Cognitive Dissonance Activities | Total |
|---|---|---|---|
| Under $10,000 | 20 | 8 | 28 |
| $10,000 - $19,999 | 35 | 15 | 50 |
| $20,000 - $29,999 | 40 | 23 | 63 |
| $30,000 - $39,999 | 19 | 12 | 31 |
| $40,000 - $49,999 | 25 | 10 | 35 |
| $50,000 - $59,999 | 30 | 14 | 44 |
| $60,000 - $69,999 | 8 | 12 | 20 |
| $70,000 - $79,999 | 19 | 10 | 29 |
| $80,000 - $89,999 | 15 | 6 | 21 |
| Over $90,000 | 28 | 16 | 44 |
| Decline to answer | 53 | 19 | 72 |
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
Ran from Dec 2023 to primary completion in Mar 2025, 15 months.
Results were first posted in Nov 2025, 8 months after primary completion.
Of 56 industry-sponsored interventional studies with no phase under Tobacco Use, half reached primary completion within 2 months of starting (the median), counting those still running; a quarter within 1 and three quarters within 5. This study's 15 months is above that.
Counting every sponsor, half of 223 studies reached it within 16 months; a quarter within 5 and three quarters within 33.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.
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Oregon Research Behavioral Intervention Strategies, Inc. →