An observational study in Heart Failure, sponsored by Mount Sinai Hospital, Canada. Recruiting at 1 site in Canada. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2023-01-05.
Sponsored by Mount Sinai Hospital, Canada · Observational
The goal of this observational study is to learn about heart function and high lung blood pressure in patients with heart failure. The main question[s] it aims to answer are whether we can improve the ability to predict patients who will have complications after they receive treatment including heart transplant and left ventricular assist devices.
Prospective cohort study of patients with heart failure with reduced ejection fraction that are referred for diagnostic right heart catheterization as part of their evaluation for candidacy for advanced heart failure therapies.
1,105 studies on the registry are indexed under Hypertension, Pulmonary; 234 are open to participants now.
This study's planned enrollment of 74 is below the median of 116 across 386 observational studies indexed under Hypertension, Pulmonary.
Browse Hypertension, Pulmonary studies →Mount Sinai Hospital, Canada is the lead sponsor of 157 studies on the registry; 33 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients assessed in the advanced heart failure program for heart transplant candidacy at the University of Toronto referred for right heart catheterization.
Exclusion Criteria:
Severe valvular or complex congenital heart disease Short-term mechanical circulatory support for progressive cardiogenic shock (e.g. extracorporeal membrane oxygenation) Acute coronary syndrome or revascularization occurred within 7 days prior to the RHC.
Pregnant or breast-feeding Known hypersensitivity to sodium nitroprusside Advanced liver dysfunction Reduced capacity or inability to provide informed consent
Procedure
Mean pulmonary artery pressure
Hemodynamic measurement
Time frame: First study 1 day visit
right ventricular end systolic elastance
Hemodynamic measurement
Time frame: First study 1 day visit
pulmonary arterial elastance
hemodynamic measurement
Time frame: First study 1 day visit
Right ventricular failure after heart transplant
Clinical outcome
Time frame: 1 year
Right ventricular failure after left ventricular assist device
Clinical outcome
Time frame: 1 year
right ventricular pulmonary arterial elastance coupling response to vasodilator
Hemodynamic measurement
Time frame: First study 1 day visit
Plan to share: Undecided — Agreements to share participant data can be requested after study completion and publication.
No publications or documents are linked to this record.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Mount Sinai Hospital, Canada