An observational study in Pituitary Tumors, sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University. Status unknown at 1 site in China. Per ClinicalTrials.gov, last updated 2022-12-02.
Sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University · Observational
DNA methylation is one of the important ways of protein post-translational modification.Pituitary adenoma (PA) is a benign neuroendocrine tumor that originates from adenohypophysial 45 cells, and accounts for 10%-20% of all primary intracranial tumors. However some PAs can present with high invasiveness and irregular growth, which tend to compresses the optic chiasm and third ventricle, encase the internal carotid artery, and affect hormone secretion from the pituitary gland and hypothalamus. In this study we focus on the mechanism of DNA methylation on the invasiveness of pituitary tumors.
175 studies on the registry are indexed under Pituitary Neoplasms; 48 are open to participants now.
This study's planned enrollment of 500 is above the median of 150 across 71 observational studies indexed under Pituitary Neoplasms.
Browse Pituitary Neoplasms studies →Second Affiliated Hospital, School of Medicine, Zhejiang University is the lead sponsor of 1,058 studies on the registry; 511 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The patients with PAs who underwent TSS at The Second Affiliated 62 Hospital Zhejiang University School of Medicine was retrospectively analyzed.
Exclusion Criteria:
Other: no interventions between two groups
Other: no interventions between two groups
no interventions between two groups
Residual tumor size
Tumor size was evaluated by postoperative MRI
Time frame: 1 week after surgery
tumor recurrence
During the follow-up, the tumor recurrence was observed closely
Time frame: three years
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Dec 2021. You cannot join it, but the record below documents what was studied.
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Second Affiliated Hospital, School of Medicine, Zhejiang University