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Active, not recruitingNCT05576493Updated Aug 30, 2023

Combined Phacoemulsification and Diode Laser Therapy in Chronic Angle Closure Glaucoma

An interventional study of phaco+MP-TSCPC and phaco+TSCPC in Angle Closure Glaucoma, sponsored by Cairo University. Active, not recruiting at 1 site in Egypt. Open to participants aged 20 Years to 70 Years. Per ClinicalTrials.gov, last updated 2023-08-30.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Oct 2023, 3 years 1 month ago, but the record still lists the study as active, not recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
88
Allocation
Randomized
Ages
20 Years to 70 Years
Sex
All
01

Study summary

comparing different types of cuclophotocoagulation with cataract extraction to cataract extraction and goniocynechiolysis in cases of chronic angle closure glaucoma

Read the detailed description

Evaluation of the safety of MP-TSCPC , CW-TSCPC and endoscopic cyclophotocoagulation when combined with phacoemulsification in cases with CACG Comparing the efficacy of the combined procedures in control of the IOP and the success rate versus lens extraction combined with synechiolysis

02

Conditions studied

  • Angle Closure Glaucoma

Keywords

  • angle closure glaucoma
  • cyclophotocoagulation
03

In context

Glaucoma, Angle-Closure

91 studies on the registry are indexed under Glaucoma, Angle-Closure; 17 are open to participants now.

This study's planned enrollment of 88 is above the median of 57 across 58 interventional studies indexed under Glaucoma, Angle-Closure.

Browse Glaucoma, Angle-Closure studies →

Lead sponsor

Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients between 20 to 70 years

chronic angle closure glaucoma

Exclusion criteria

Exclusion Criteria:

  • Patients in acute attack of angle closure.
  • Patients with previous filtering surgery or cycloablative procedure
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
88 participants (estimated)

Study arms

  • Experimental
    A:phaco+MP-TSCPC

    22 patients with primary angle closure glaucoma will undergo phacoemulsification and micropulse cyclophotocoagulation

    Procedure: phaco+MP-TSCPC

  • Experimental
    B:phaco+TSCPC

    22 patients with primary angle closure glaucoma will undergo phaco and transscleral cyclophotocoagulation

    Procedure: phaco+TSCPC

  • Experimental
    C:phaco+endocyclophotocoagulation

    22 patients with primary angle closure glaucoma will undergo phaco and endocyclophotocoagulation after cataract removal

    Procedure: phaco+endocyclophotocoagulation

  • Experimental
    D:phaco GSL

    22 patients with primary angle closure glaucoma will undergo phaco and goniosynechiolysis

    Procedure: phaco GSL

Interventions

  • Procedurephaco+MP-TSCPC

    The procedure starts with performing the cyclophotocoagulation using the Micropulse P3 device (IQ 810 Laser Systems; Iridex, Mountain View, CA, USA) at 2500 mW with a duration of 90 seconds in each hemisphere at a 31.3% duty cycle under local anesthesia and then performing phacoemulsification and IOL implantation.

  • Procedurephaco+TSCPC

    The procedure starts with performing the cyclophotocoagulation using the IRIDEX's G probe device (IRIDEX Corp. Mountain View, CA, USA) at 1500 to2000 mW with a duration of 1500 ms applying about 15 shots in one hemisphere only under local anesthesia and then performing phacoemulsification and IOL implantation.

  • Procedurephaco+endocyclophotocoagulation

    phacoemulsification will be done and endocyclophotocoagulation will be done after cataract extraction

  • Procedurephaco GSL

    phacoemulsification will be done and then the angle is visualized by direct goniolens then the synechia are dissected by cohesive viscoelastic.

06

What researchers measure

Primary outcomes

  1. the percentage of intraocular pressure change

    measuring the intraocular pressure after 1M, 3M and 6M

    Time frame: 6 Months

Secondary outcomes

  1. percent change of antiglaucoma medications

    the number of medication before and after the procedure

    Time frame: 6 Months

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 30, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05576493
Lead sponsor
Cairo University
Responsible party
Fayrouz Aboalazayem (lecturer, Cairo University) — Principal investigator
First posted
Oct 12, 2022
Start date
Aug 11, 2022
Primary completion
Oct 1, 2023 (estimated)
Completion
Dec 1, 2023 (estimated)
Last update
Aug 30, 2023

Study contacts

Ahmed Abdelrahman, PhD
study chair · kasr alainy

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Aug 2023. You cannot join it, but the record below documents what was studied.

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