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CompletedNCT05537974Updated Jan 18, 2023

Open Suction vs. Closed Suction in ARDS

An interventional study of Endotracheal aspiration in Acute Respiratory Distress Syndrome, sponsored by Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital. Completed at 1 site in Turkey. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-01-18.

Sponsored by Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital · Not applicable, Interventional, and Screening

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years and older
Sex
All
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Study summary

The alveoli tend to collapse in patients with ARDS. Endotracheal aspiration may increase alveolar collapse by decreasing the end-expiratory lung volume. The hypothesis is that closed endotracheal aspiration led to less end-expiratory volume loss when compared to open endotracheal aspiration.

02

Conditions studied

  • Acute Respiratory Distress Syndrome

Keywords

  • Endotracheal aspiration, Electric impedance tomography
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In context

Respiratory Distress Syndrome

1,597 studies on the registry are indexed under Respiratory Distress Syndrome; 312 are open to participants now.

This study's enrollment of 20 is below the median of 60 across 961 interventional studies indexed under Respiratory Distress Syndrome.

Browse Respiratory Distress Syndrome studies →

Lead sponsor

Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital is the lead sponsor of 13 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

Mechanically ventilated due to ARDS

Exclusion criteria

Exclusion Criteria:

Hemodynamically unstable Air leaks syndrome (pneumothorax) Higher level of FiO2 (>60%) Chronic obstructive pulmonary disease

05

Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Other
    Open Suction

    Endotracheal aspiration will perform after the patient disconnect from mechanical ventilation

    Procedure: Endotracheal aspiration

  • Other
    Closed Suction

    Endotracheal aspiration will perform without disconnection from mechanical ventilation

    Procedure: Endotracheal aspiration

Interventions

  • ProcedureEndotracheal aspiration

    Clearance of endotracheal secretions via a catheter.

06

What researchers measure

Primary outcomes

  1. End expiratory lung volume (EELV)

    End expiratory lung impedance (EELI) will be measured wit electric impedance tomography. Change in EELI representative of change in EELV.

    Time frame: One minute before suctioning, 1, 10, 20, 30 minutes after suctioning

07

Study locations

1 site
  • University of Health Sciences Turkey, Dr Suat Seren Chest Diseases and Chest Surgery Training and Research Hospital, Intensive Care Unit
    İzmir, 35110, Turkey
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 18, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05537974
Lead sponsor
Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Responsible party
Cenk Kirakli, M.D. (Professor Doctor, Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital) — Principal investigator
First posted
Sep 13, 2022
Start date
Sep 15, 2022
Primary completion
Oct 31, 2022
Completion
Oct 31, 2022
Last update
Jan 18, 2023

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.

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