An observational study in Cardiovascular Diseases, Hypertension and Diet, Healthy, sponsored by The University of Texas at Arlington. Completed at 1 site in United States. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-05.
Sponsored by The University of Texas at Arlington · Observational
The role of diet in preventing hypertension and cardiovascular diseases in African Americans, who have a much higher risk of developing these diseases, is not well understood. Therefore, this project will investigate whether African Americans following a 100% plant-based diet have more optimal blood pressure, vascular function, and blood lipid profiles, along with lower systemic inflammation relative to African Americans following a typical American diet.
5,025 studies on the registry are indexed under Cardiovascular Diseases; 930 are open to participants now.
This study's enrollment of 19 is below the median of 600 across 1,524 observational studies indexed under Cardiovascular Diseases.
Browse Cardiovascular Diseases studies →The University of Texas at Arlington is the lead sponsor of 38 studies on the registry; 11 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 2 (25%) have results posted.
Counted across the registry records on this site, refreshed daily.
Community sample from the greater Dallas-Fort Worth Metroplex area.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
African American individuals who self-report adhering to a typical American diet prior to enrolling in the study.
Other: Typical American Diet
African American individuals who self-report adhering to a plant-based diet prior to enrolling in the study.
Other: Plant-Based Diet
Participants self-reported adherence to a typical American diet prior to enrolling in the study. This factor determined cross-sectional group allocation.
Participants self-reported adherence to a 100% plant-based diet prior to enrolling in the study. This factor determined cross-sectional group allocation.
Lipid profile (Total-C, LDL-C, VLDL-C, HDL-C, TG)
Time frame: Day 1
C-reactive protein
Time frame: Day 1
Post-occlusive brachial artery flow-mediated dilation (% change in brachial artery diameter from resting baseline)
Time frame: Day 1
Post-occlusive forearm reactive hyperemia (% change in brachial artery blood velocity from resting baseline)
Time frame: Day 1
Pulse wave velocity (carotid-to-femoral)
Time frame: Day 1
Augmentation index (AIx@HR75)
Time frame: Day 1
Cerebral vascular reactivity (% change in cerebrovascular conductance index from resting baseline)
Time frame: Day 2
Local cutaneous thermal hyperemia (% change in cutaneous vascular conductance from resting baseline)
Time frame: Day 2
Peripheral blood pressure (systolic, diastolic, mean)
Time frame: Day 1
Central blood pressure (systolic, diastolic, mean)
Time frame: Day 1
Plan to share: Yes — Data Availability Statement: All raw data were collected and generated at the University of Texas at Arlington. Data supporting the findings and conclusions of this study are available from the corresponding author upon request.
This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.
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The University of Texas at Arlington