An observational study in Cardiac Arrest, Cardiopulmonary Resuscitation and Extracorporeal Membrane Oxygenation Complication, sponsored by Charite University, Berlin, Germany. Status unknown at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-05-16.
Sponsored by Charite University, Berlin, Germany · Observational
A cardiac arrest event has severe impact on the patient´s health-related quality of life. Survival of cardiac arrest does not innately translate to favorable quality of life. In particular, highly invasive resuscitation strategies, including extracorporeal cardio-pulmonary resuscitation (ECPR) due to therapy-refractory cardiac arrest, may have impact on long-term outcomes. Therefore, apart from acute medical treatment and physical rehabilitation, long-term effects on cardio-pulmonary, physical and neuro-psychiatric functions after cardiac arrest survival have to be evaluated and optimized. We plan to investigate a bundle of cardio-pulmonary, physical and neuro-psychiatric functions in patients who survived a therapy-refratory cardiac arrest with ECPR.
984 studies on the registry are indexed under Heart Arrest; 227 are open to participants now.
This study's planned enrollment of 30 is below the median of 196 across 394 observational studies indexed under Heart Arrest.
Browse Heart Arrest studies →Charite University, Berlin, Germany is the lead sponsor of 854 studies on the registry; 127 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult patients who suffered from cardiac arrest and were treated with ECPR.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Adult patient who survived therapy-refractory cardiac arrest with extracorporeal cardiopulmonary resuscitation (ECPR).
Left ventricular ejection fraction (LVEF)
LVEF measured with transthoracic echocardiography.
Time frame: LVEF witihin one year after index cardiac arrest event.
Cognitive function
Cognitive function measured with a standardized questionnaire and following established scores: 1. Mini-mental-status-test \[0-30 points; higher score means better outcome\], 2. Cerebral Performance Categories Scale \[1-5; lower score means better outcome\].
Time frame: Cognitive function witihin one year after index cardiac arrest event.
Sign and symptoms of heart failure
Sign and symptoms of heart failure measured with a standardized questionnaire and following established score: European Quality of Life 5 Dimensions 3 Level Version \[0-100 points; higher score means better outcome\].
Time frame: Sign and symptoms of heart failure witihin one year after index cardiac arrest event.
Activity of daily living (ADL)
ADL measured with a standardized questionnaire and following estbalished score: Barthel index \[0-100 points; higher score means better outcome\].
Time frame: ADL witihin one year after index cardiac arrest event.
Comorbidity level
Comorbidity level measured with following established score: Charlson comorbidity index \[0-24 points; lower score means better outcome\].
Time frame: Comorbidity level witihin one year after index cardiac arrest event.
Number of cardiovascular medications
Number of cardiovascular medications documented with a standardized questionnaire.
Time frame: Number of cardiovascular medication witihin one year after index cardiac arrest event.
Cardiac stress test: Ergometry
Quantitative test to evaluate cardiopulmonary exercise tolerance and physical capacity by using a bicycle.
Time frame: Physical function witihin one year after index cardiac arrest event.
Cardiac stress test: Walking distance
Quantitative test to evaluate endurance and aerobic capacity by walking for six minutes (six minute walk test).
Time frame: Physical function witihin one year after index cardiac arrest event.
Vital function: Blood pressure
Non-invasive blood pressure measurement at rest (unit: mmHg).
Time frame: Blood pressure witihin one year after index cardiac arrest event.
Vital function: Electrocardiogram (ECG)
12-lead ECG measurement at rest.
Time frame: ECG activity witihin one year after index cardiac arrest event.
Vital function: Peripheral oxygen saturation
Peripheral oxygen saturation measurement at rest by using pulsoximetry (unit: percent).
Time frame: Peripheral oxygen saturation witihin one year after index cardiac arrest event.
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in May 2023. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Charite University, Berlin, Germany →