An interventional study of reverse conversion technique in Laparoscopic Surgery, Acute Appendicitis With Rupture and Sepsis, sponsored by Zagazig University. Completed at 1 site in Egypt. Open to participants aged 16 Years to 65 Years. Per ClinicalTrials.gov, last updated 2022-03-17.
Sponsored by Zagazig University · Not applicable, Interventional, and Treatment
A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in management of Acute Perforated Appendicitis
Introduction: Acute appendicitis (AA), a frequent intra-abdominal surgical pathology, necessitates a thorough awareness of its symptoms, examination, diagnosis, and total surgical management. The surgical approach to AA is appendectomy; nevertheless, the medical literature continues to argue the merits of open vs laparoscopic surgery. As with other laparoscopic surgical techniques, the literature reports lower discomfort, earlier resumption of oral feeding and shorter hospital stay following laparoscopic appendectomy (LA) as compared to open appendectomy (OA). Additionally, laparoscopy has some drawbacks such as greater cost and lengthier operating durations as compared to open surgery. The goal of this clinical study: was to compare open appendectomy versus laparoscopic conversion from open (reverse conversion) for the treatment of acute perforated appendicitis in our setting. Patients and procedures: 426 patients had perforated appendectomy and divided between two groups: group A (interventional) 213 patients who were subjected to the reverse conversion technique and group B (control)213 patients who were operated by the open technique. The key end goals for comparing both groups were the rates of intraabdominal abscess, rates of wound infection, rates of ileus and rates of reoperation. The hospital length of stay and the operative time were used as secondary end goals for comparison.
2,416 studies on the registry are indexed under Sepsis; 541 are open to participants now.
This study's enrollment of 426 is above the median of 102 across 1,165 interventional studies indexed under Sepsis.
Browse Sepsis studies →Zagazig University is the lead sponsor of 459 studies on the registry; 77 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
the group who was subjected to the reverse conversion technique
Procedure: reverse conversion technique
the control group who was completed by open technique
converting open appendectomy to laparoscopic technique for proper control of intraabdominal sepsis
Also known as: laparoscopic lavage
the rates of intraabdominal abscess
rates of complications
Time frame: 3 months post operative
rates of wound infection
rates of complications
Time frame: 3 months post operative
rates of ileus
Time frame: Baseline (Hospital admission)
rates of reoperation
Time frame: 3 months post operative
The hospital length of stay
the length of hospital stay
Time frame: up to 3 months
the operative time
Time of performing the procedures
Time frame: Intraoperative
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.